Articles tagged "B cells"

2015 American Transplant Congress
LFA-1 Is Crucial for Germinal Center Reconstruction After T cell Depletion and IL-21 Biased Antibody-Mediated Rejection
J. Kwun,¹ B. Oh,¹ H. Song,¹ A. Farris,¹ A. Kirk,² W. Mahle,¹ S. Knechtle.¹
¹Surgery, Emory Transplant Center, Atlanta, GA; ²Surgery, Duke University, Durham, NC.
[Background] Lymphocyte depletion prior to transplantation is beneficial in reducing initial maintenance immunosuppression in transplantation. However, despite its excellent efficacy in controlling T cell mediated…
2015 American Transplant Congress
Efficacy and Safety of Desensitization Protocol Based On Rituximab Plus MMF in ABO-Incompatible Kidney Transplantation Without Splenectomy
K. Takahashi,¹ K. Saito,² S. Takahara,³ S. Fuchinoue,⁴ T. Yagisawa,⁵ A. Aikawa,⁶ Y. Watarai,⁷ N. Yoshimura,⁸ K. Tanabe,⁴ K. Morozumi,⁹ M. Shimazu.¹⁰
¹Niigata Organ Transplant Foundation, Niigata, Japan; ²Graduate School of Medical ＆ Dental Sciences, Niigata University, Niigata, Japan; ³Osaka University Graduate School of Medicine, Osaka, Japan; ⁴Tokyo Women's Medical University, Tokyo, Japan; ⁵Jichi Medical University Hospital, Tochigi, Japan; ⁶Toho University, Faculty of Medicine, Tokyo, Japan; ⁷Nagoya Daini Red Cross Hospital, Aichi, Japan; ⁸Kyoto Prefectural University of Medicine, Kyoto, Japan; ⁹Masuko Memorial Hospital, Aichi, Japan; ¹⁰Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.
Purpose: An open-label, single arm, multicenter clinical study has been conducted in Japan for prospective examination of the efficacy and safety of desensitization protocol with…