Articles tagged "B cells"

2015 American Transplant Congress
B Cell Depletion With an Anti-CD20 Antibody Enhances Alloreactive Memory T Cell Response After Transplantation
J. Marino, P. Crosby Bertorini, J. Paster, A. Trowell, K. Briggs, L. Maxwell, G. Benichou.
Surgery Department, Center for Transplantation Sciences, Massachusetts General Hospital / Harvard Medical School, Boston, MA.
Pre-transplant B cell depletion in NHP with Rituximab (IgG1 anti-CD20 mAb) combined with cyclosporin A has been shown to promote the survival of islets allografts.…
2015 American Transplant Congress
IgM+ Antigen Binding B Cells in Peripheral Blood Regulate IFNγ Production in Response to HLA Proteins
L. McLaughlin,¹ K. Shiu,¹ G. Lombardi,¹ J. Spencer,² R. Vaughan,¹ A. Dorling.¹
¹MRC Centre for Transplantation, King's College London, London, United Kingdom; ²Peter Gorer Department of Immunobiology, King's College London, London, United Kingdom.
Chronic antibody mediated rejection (CAMR) is a major cause of graft loss in renal transplant recipients. Previous work utilising an IFNγ ELISPOT assay revealed two…