2015 American Transplant Congress
Pre-Transplant Anti-LG3 Antibodies Enhance Allograft Dysfunction in Kidney Transplant Recipients With Delayed or Slow Graft Function
CHUM Research Center, Montreal, Canada.
Background: We have previously shown that autoantibodies to the LG3 fragment of perlecan enhance vascular damage in a murine model of vascular rejection, particularly when…2015 American Transplant Congress
Germinal Centre Autoimmunity Mediates Progression of Allograft Vasculopathy, With Essential Help Provided By T Follicular Cells
Dept of Surgery, University of Cambridge, Cambridge, United Kingdom.
Introduction: : In our previous work we have shown that donor CD4 T cells within heart grafts initiate anti-nuclear autoantibody responses. Here we clarify the…2015 American Transplant Congress
Donor MHC Independent Rejection of Islet Allografts in Autoimmune NOD Mice
In autoimmune Type 1 diabetes (T1D), pancreatic islet allografts have somewhat limited long-term survival, both in T1D human subjects and in spontaneously diseased non-obese diabetic…
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