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Articles tagged "Autoimmunity"

  • 2015 American Transplant Congress

    Mechanisms Underlying Treg Dysfunction in DAIH- Role for PD-L1?

    A. Arterbery,1 M. Martinez,2 S. Lobritto,2 Y. Avitzur,3 K. Raddassi,1 M. Kleinewietfeld,4 U. Ekong.1

    1Yale, NH; 2Columbia, NY; 3HSC, Toronto, Canada; 4Dresden University of Technology, Dresden, Germany.

    Background: we have previously shown that ex vivo Tregs from patients with DAIH demonstrate differentiation plasticity towards TH17. To understand the mechanisms underlying this we…
  • 2015 American Transplant Congress

    Preformed IgA Antibodies to B2-Glycoprotein Is an Indepedent Risk Factor for Graft Thrombosis and Early Graft Loss After Renal Transplantation

    J. Morales,1 M. Serrano,3 J. Martinez,2 D. Perez,2 M. Sevilla,2 A. Amdres,3 E. Gonzalez,3 E. Paz-Artal,2 A. Serrano.2

    1Research Institute, hospital 12 de Octubre, Madrid, Spain; 2Immunology, Hospital 12 de Octubre, Madrid, Spain; 3Nephrology, Hospital 12 de Octubre, Madrid, Spain.

    Vessel trombosis represent the first cause of early graft loss (EGL)alter renal transplantation (RT). Our group recently described that preformed IgA antibodies to B2-Glycoprotein (…
  • 2015 American Transplant Congress

    miR-155 Different Roles in UCB iTreg and nTreg

    Y. Lu, L. Lu.

    Liver Transplantation Center of First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.

    OBJECTIVES:miR-155 has been associated with both innate and adaptive immune responses. SOCS1, which is involved in Treg survival and function, is a direct target of…
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