2015 American Transplant Congress
Estimated Prevalence of HIV in Kidney Transplant Candidates
Surgery, Johns Hopkins University, Baltimore, MD.
The passage of the HOPE Act in November 2013 mandated research into HIV+ to HIV+ organ transplantation. To date, the prevalence of HIV in the…2015 American Transplant Congress
CD8 T Cell Biomarkers Improves the Capacities of the Kidney Transplant Failure Score for the Long-Term Prognostic of Kidney Graft Failures
Background. Kidney transplantation is acknowledged as the treatment of choice for patients in end-stage renal disease compared to dialysis. We hypothesized that the efficiency of…2015 American Transplant Congress
The Potential Use of the Plasma Biomarker CXCL9 (MIG), Interleukin 2 Receptor alpha (IL2Rα) and SCGF-b as Predictors of Renal Graft Rejection
Background: Early detection of rejection in kidney transplantation is crucial, and predictive plasma biomarkers are highly desirable as non-invasive tests.Methods: From a cohort of 120…2015 American Transplant Congress
Reduction of Tacrolimus With Everolimus Addition in Maintenance Immunosuppression Improves Calcineurin Inhibitor-Induced Arteriolopathy in Kidney Allografts
Objectives: Although conversion of calcineurin inhibitor (CNI)-based immunosuppression to everolimus (EVR) has been shown to improve graft function, no histopathological evidence has been reported. The…2015 American Transplant Congress
Mycophenolic Acid Area-Under-Curve (MPA AUC) Levels Sufficient to Prevent Donor-Specific Antibody (DSA) Formation Are Not Associated With Higher Rates of CMV/EBV/BK Viral Infections
PinnacleHealth, Harrisburg, PA.
Background: Prevention of DSA formation and antibody-mediated rejection mandates therapeutic doses of immunosuppressive agents, including MPA. We have shown that MPA AUC monitoring and dose…2015 American Transplant Congress
Predictive Value of Cardiovascular Risk Assessment Tools in Kidney Transplantation
Surgery, Albert Einstein College of Medicine, Bronx, NY.
Cardiovascular disease is a major cause of morbidity and mortality following kidney transplantation. Many cardiovascular risk screening tools have been developed, but they have never…2015 American Transplant Congress
Proteinuria as Non-Invasive Marker for Renal Allograft Histology and Survival: A Population-Based Study
University Hospitals Leuven, Leuven, Belgium.
Background:Proteinuria is routinely measured for assessment of renal allograft status, but its diagnostic value for transplant pathology and herewith-related prognostic value remain unclear.Methods:We included 1518…2015 American Transplant Congress
Molecular Classifiers Accurately Measure the Degree of Fibrosis in Human Kidney Transplant Biopsies
University of Alberta, Edmonton, Canada.
Irreversible injury in organ transplants is an important clinical parameter, and is estimated by histology as the observed “ci” lesion, but with considerable inter-observer variability…
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