ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Articles tagged "Antigen presentation"

  • 2017 American Transplant Congress

    Preventing Alloimmune Rejection in Heart Transplantation by Tolerogenic Dendritic Cells Induced by GDF15 Through Up-Regulation of IDO and Inhibition of the NFκB Signalling Pathway.

    Y. Zhang,1,3 G. Zhang,1 L. Moszczynski,1 D. Zhao,1,3 P. Abulizi,1 D. Quan,2 T. Mele,2 K. Liu,3 X. Zheng.1,2

    1Pathology, University of Western Ontario, London, ON, Canada; 2Surgery, University of Western Ontario, London, ON, Canada; 3Cardiovascular Surgery, Jilin University, Cahngchun, China

    Rationale: Growth differentiation factor 15 (GDF15) can inhibit DC maturation, yet whether it can generate tolerogenic dendritic cells (Tol-DCs) to induce immune tolerance in heart…
  • 2017 American Transplant Congress

    Imaging Cell Biology in Transplantation.

    T. Ueno,1 M. McGrath,1 M. Yeung,1 K. Jung,2 Y. Kihara,3 O. Konno,3 Y. Nakamura,3 H. Iwamoto,3 S. Yun,2 A. Chandraker.1

    1Transplantation Research Center, Brighma and Women's Hospital, Harvard Medical School, Boston, MA; 2Department of Dermatology, Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; 3Transplantation Surgery, Tokyo Medical University, Hachioji, Tokyo, Japan

    Background: Following transplantation, a set of coordinated events occurs within the recipient immune system. Immature dendritic cells (DCs) migrate to sites of inflammation, become activated…
  • 2016 American Transplant Congress

    Imaging Cell Biology In Vivo with Intravital-Microscopy.

    T. Ueno,1 M. Yeung,1 N. Igarashi,3 T. Yokoyama,2 Y. Kihara,2 O. Konno,2 Y. Nakamura,2 H. Iwamoto,2 T. Ikeda,3 M. McGrath,1 M. Sayegh,1 A. Chandraker.1

    1Renal Division, Transplantation Research Center, Brigham and Women's Hospital, Boston, MA; 2Transplant Surgery, Tokyo Medical Univ., Hachioji, Tokyo, Japan; 3Intensive Care Medicine, Tokyo Medical Univ., Hachioji, Tokyo, Japan.

    Background: Despite current immunosuppressive therapy, many recipients endure multiple episodes of acute rejection. The interplay between dendritic cells (DCs) and T cells plays a central…
  • 2016 American Transplant Congress

    Tissue Priming of Plasmacytoid Dendritic Cells Enhances Their Phagocytosis and Lowers the Threshold for Subsequent Toll-Like Receptor 7/9 Activation.

    J. Ruben,1 G. Garcia-Romo,1 E. Breman,1 S. van der Kooij,1 A. Redeker,2 R. Arens,2 C. van Kooten.1

    1Nephrology, Leiden University Medical Centre, Leiden, Netherlands; 2Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, Netherlands.

    Plasmacytoid dendritic cells (pDC) have a pivotal role in clearing viral infections, and can regulate tolerance or immunity depending on their activation status. We have…
  • 2016 American Transplant Congress

    High PD-L1/CD86 MFI Ratio and IL-10 Secretion Characterize Maturation-Resistant Human Regulatory Dendritic Cells (DCregs) Generated for Clinical Testing in Transplantation.

    A. Zahorchak,1 L. Butterfield,2,3 C. Macedo,1 D. Hamm,4 D. Metes,1,3 A. Thomson.1,3

    1Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh; 2Medicine, University of Pittsburgh, Pittsburgh; 3Immunology, University of Pittsburgh, Pittsgurgh; 4Adaptive Biotech, Seattle.

    Regulatory dendritic cells (DCregs) have shown considerable potential for safe and effective prolongation of allograft survival in pre-clinical models. In humans, DCregs with purity >84%…
  • 2016 American Transplant Congress

    Transfer of Donor-Derived Exosomes to Recipient Ag-Presenting Cells Is Critical for Allograft Recognition.

    Q. Liu,1 D. Rojas-Canales,1 S. Divito,1 W. Shufesky,1 A. Larregina,2 A. Morelli.1

    1Surgery, University of Pittsburgh, Pittsburgh, PA; 2Dermatology, University of Pittsburgh, Pittsburgh, PA.

    After organ transplantation, T cells are primed against donor MHC molecules by donor dendritic cells (DCs) mobilized from the graft. Nevertheless, evidence suggests that donor…
  • 2016 American Transplant Congress

    Immunologic Basis for Immunocloaking.

    L. Brasile,1 K. Kizjakina,1 N. Henry,1 B. Stubenitsky.2

    1BREONICS Inc., Watervliet, NY; 2Plastic Surgery, University of Utrecht, Utrecht, Netherlands.

    A novel organ-specific immunomodifying therapy referred to as immunocloaking (IC) provides protection from early allograft rejection without immunosuppressive drugs. The IC binds to the surfaces…
  • 2016 American Transplant Congress

    Activation of Alloreactive T Cells by Allogeneic Exosomes and Cells Cross-Dressed with Allogeneic MHC Molecules.

    M. Babiker-Mohamed, J. Marino, P. Crosby, G. Benichou.

    Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital & Harvard Medical School, Boston, MA.

    Our recent studies have documented the presence of high numbers of recipient antigen presenting cells (APCs) displaying donor MHC molecules (cross-dressed) on their surface after…
  • 2015 American Transplant Congress

    Dendritic Cells in Kidney Transplant Biopsies Are Associated With Poor Allograft Survival

    I. Batal,1 S. De Serres,1 K. Safa,1 A. Waaga,1 M. Onozato,2 N. Najafian,1 A. Chandraker.1

    1Brigham and Women's Hospital/Harvard Medical School, Boston, MA; 2Massachusetts General Hospital/Harvard Medical School, Boston, MA.

    Background: Long-term renal allograft survival continues to lag behind the progress seen in short-term transplant outcomes. Dendritic cells (DCs) are the most efficient antigen-presenting cells,…
  • 2015 American Transplant Congress

    Proteomic Study Identified a Distinct Panel of Protein Expression in the ATP-Competitive MTOR Kinase Inhibitor Conditioned Dendritic Cells Compared to Rapamycin

    T. Ma,1 Y. Pei,1 Y. Han,2 R. Tao.1

    1Department of Hepatobiliary-Pancreatic Surgery, Zhejiang Provincial Peoples' Hospital, Hangzhou, Zhejiang Province, China; 2Department of Pathology, Zhejiang Provincial Peoples' Hospital, Hangzhou, Zhejiang Province, China.

    Purpose: Dendritic cells (DCs) are key players in both innate and adaptive immunity, as well as in immune tolerance. The mammalian target of rapamycin (mTOR)…
  • « Previous Page
  • 1
  • …
  • 5
  • 6
  • 7
  • 8
  • Next Page »

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences