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Articles tagged "Anticoagulation"

  • 2019 American Transplant Congress

    When to Hold: Apixaban in Renal Transplant Recipients

    V. H. Do1, D. Haakinson2, K. D. Belfield1

    1Yale New Haven Hospital, New Haven, CT, 2Yale School of Medicine, New Haven, CT

    *Purpose: Renal transplant recipients (RTRs) may develop deep venous thrombosis (DVT), pulmonary embolism (PE), or atrial fibrillation requiring treatment with oral anticoagulation. There is limited…
  • 2019 American Transplant Congress

    Postoperative Atrial Fibrillation in Kidney Transplant Recipients: A Retrospective Study Evaluating Risk of Anticoagulation

    P. Serrano Rodriguez1, A. Vijayakumar2, P. D. Strassle3, K. Szempruch1, C. S. Desai1, A. Vijay1, A. H. Toledo1, D. A. Gerber1

    1Abdominal Transplant SUrgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3General Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC

    *Purpose: Patients with atrial fibrillation (AF) have a higher risk of mortality and adverse cardiovascular events. Pre-operative AF has around 5-9% prevalence and roughly 5%…
  • 2019 American Transplant Congress

    Effect of Enoxaparin Prophylaxis on Early VTE Post Lung Transplant

    S. Marshall1, K. Tsveybel1, S. Boukedes1, P. Burkett2, R. Chepuri2, A. Coppolino3, M. Divo2, S. El-Chemaly2, S. Keller2, J. Kennedy2, H. Mallidi3, G. Mody3, T. Thaniyavarn2, A. Trindade2, K. Townsend1, H. Goldberg2

    1Lung Transplant, Brigham & Women's Hospital, Boston, MA, 2Pulmonary Division, Brigham & Women's Hospital, Boston, MA, 3Thoracic Surgery, Brigham & Women's Hospital, Boston, MA

    *Purpose: Thromboembolic complications are common post-transplant leading to significant morbidity. We instituted early enoxaparin prophylaxis (ppx) in lung transplant recipients (LTR) due to an observed…
  • 2019 American Transplant Congress

    Safety and Efficacy of Anti Xa Inhibitors Post-Transplant with Concomitant Calcineurin Inhibitors

    K. A. McMurry1, J. Shuster2, K. Bain2, T. Horwedel3, J. Hartupee2

    1Michigan Medicine, Ann Arbor, MI, 2Barnes-Jewish Hospital, St. Louis, MO, 3Veloxis Pharmaceuticals, Cary, NC

    *Purpose: Despite demonstrated benefits of Anti-Xa Inhibitors (ATIs) in the general population, ATIs have not gained uniform acceptance in SOT due to lack of supportive…
  • 2019 American Transplant Congress

    Apixaban Therapy Is Safe And Effective In Most Organ Transplant Populations

    A. Brown, S. Palkimas, W. Ally

    University of Virginia Health System, Charlottesville, VA

    *Purpose: The bleed rates from the apixaban pivotal trial were 12.1% for non-major and 3.8% major bleeds. However outcomes in transplant recipients are less defined,…
  • 2019 American Transplant Congress

    Anti-Xa Level Monitoring for Treatment Dose Enoxaparin in Liver/Intestine Transplant Recipients

    J. Sullivan, J. Jebrock, J. Revollo, M. Perez, J. Garcia, T. Beduschi

    Jackson Memorial Hospital, Miami, FL

    *Purpose: Evaluate the use of anti-Xa levels in therapeutic enoxaparin dosing in liver/intestine transplant recipients.*Methods: A single-center retrospective chart review was conducted on liver/intestine transplant…
  • 2019 American Transplant Congress

    Direct Oral Anticoagulants: An Evaluation of the Safety and Efficacy in Solid Organ Transplant Recipients

    T. Pasley, A. Logan, A. Brueckner, L. Bowman, A. Silverman, A. Rumore

    Tampa General Hospital, Tampa, FL

    *Purpose: The use of direct oral anticoagulants (DOACs) has not been fully adopted by the solid organ transplant (SOT) community due to factors including, fluctuating…
  • 2018 American Transplant Congress

    The Effect of Perioperative Antiplatelet/Anticoagulant Therapy on the Incidence of Early Postoperative Thromboembolic Complications and Bleeding in Kidney Transplantation – A Dual Center Retrospective Cohort Study of 2000 Kidney Transplant Recipients

    T. van den Berg,1 R. Minnee,2 G. Nieuwenhuijs-Moeke,3 S. Bakker,4 R. Pol.1

    1Department of Surgery, University Medical Center Groningen (UMCG), Groningen, Netherlands; 2Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; 3Department of Anesthesiology, UMCG, Groningen, Netherlands; 4Department of Internal Medicine-Nephrology, UMCG, Groningen, Netherlands.

    Thromboembolic complications (TECs) are dreaded complications after kidney transplantation (KTx). Consequences are severe and can result in delayed graft function or even graft loss. Perioperative…
  • 2018 American Transplant Congress

    Anticoagulation in Pediatric Liver Transplantation; the Pros and Cons

    M. Werner,1 R. de Kleine,1 M. de Boer,1 V. de Meijer,1 R. Scheenstra,2 H-.J. Verkade,2 F. Bodewes,2 S. Bontemps,3 T. Lisman,1 R. Porte.1

    1HPB Surgery & Liver Transplantation, University Medical Center Groningen, Groningen, Netherlands; 2Pediatric Gastroenterology & Hepatology, University Medical Center Groningen, Groningen, Netherlands; 3Pediatric Intensive Care, University Medical Center Groningen, Groningen, Netherlands.

    Background: Hepatic artery thrombosis (HAT) and portal vein thrombosis (PVT) are serious causes of morbidity and mortality after pediatric orthotopic liver transplantation (OLT). To minimize…
  • 2018 American Transplant Congress

    Brain Death Conditions Intensify Inflammation and Impair Metabolic Gene Expression

    L. Zitur, P. Chlebeck, S. Odorico, T. Zens, J. Danobeitia, M. Eerhart, J. Reyes, A. D'Alessandro, K. Brunner, S. Capuano, L. Fernandez.

    University of Wisconsin, Madison.

    Rationale: Inflammation observed in Brain Death (BD) donors is linked to reduced graft function and survival compared to living donors (LD). Detailed analyses of non-human…
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