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Articles tagged "Anticoagulation"

  • 2020 American Transplant Congress

    Anticoagulation in Simultaneous Pancreas Kidney (SPK) Transplantation- On What Basis?

    J. Gopal, P. Herbert, J. Crane, F. Dor, V. Papalois, A. Muthusamy

    Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

    *Purpose: Despite technical refinements, early pancreas graft loss due to thrombosis continues to occur. Conventional coagulation tests do not detect hypercoagulability and hence is left…
  • 2020 American Transplant Congress

    Safety and Efficacy of Direct-Acting Oral Anticoagulants versus Warfarin in Kidney Transplant Recipients

    A. L. Bixby1, S. A. Shaikh2, A. S. Naik3, L. Cotiguala3, K. McMurry3, M. D. Samaniego-Picota4, V. D. Marshall5, J. M. Park3

    1University Hospitals Cleveland Medical Center, Cleveland, OH, 2Keck Medical Center of USC, University of Southern California, Los Angeles, CA, 3Michigan Medicine, Ann Arbor, MI, 4Henry Ford Transplant Institute, Detroit, MI, 5University of Michigan College of Pharmacy, Ann Arbor, MI

    *Purpose: Safety and efficacy of direct-acting oral anticoagulants (DOACs) have not been well studied in solid organ transplant. The purpose of our study was to…
  • 2020 American Transplant Congress

    Adult Liver Transplant Recipients Show Increased Fibrinolysis Resistance Compared with Pediatric Recipients: The Potential Impact of Anticoagulation between the Two Populations

    H. B. Moore, T. Nydam, R. Choudhury, A. Schulick, C. Walker, M. Wachs, M. A. Adams

    University of Colorado, Aurora, CO

    *Purpose: Fibrinolytic changes in adult liver transplant patients have previously been demonstrated large transitions from excessive fibrinolysis (hyperfibrinolysis) to fibrinolysis resistance (shutdown) within 2 hours…
  • 2019 American Transplant Congress

    Postoperative Atrial Fibrillation in Kidney Transplant Recipients: A Retrospective Study Evaluating Risk of Anticoagulation

    P. Serrano Rodriguez1, A. Vijayakumar2, P. D. Strassle3, K. Szempruch1, C. S. Desai1, A. Vijay1, A. H. Toledo1, D. A. Gerber1

    1Abdominal Transplant SUrgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3General Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC

    *Purpose: Patients with atrial fibrillation (AF) have a higher risk of mortality and adverse cardiovascular events. Pre-operative AF has around 5-9% prevalence and roughly 5%…
  • 2019 American Transplant Congress

    Effect of Enoxaparin Prophylaxis on Early VTE Post Lung Transplant

    S. Marshall1, K. Tsveybel1, S. Boukedes1, P. Burkett2, R. Chepuri2, A. Coppolino3, M. Divo2, S. El-Chemaly2, S. Keller2, J. Kennedy2, H. Mallidi3, G. Mody3, T. Thaniyavarn2, A. Trindade2, K. Townsend1, H. Goldberg2

    1Lung Transplant, Brigham & Women's Hospital, Boston, MA, 2Pulmonary Division, Brigham & Women's Hospital, Boston, MA, 3Thoracic Surgery, Brigham & Women's Hospital, Boston, MA

    *Purpose: Thromboembolic complications are common post-transplant leading to significant morbidity. We instituted early enoxaparin prophylaxis (ppx) in lung transplant recipients (LTR) due to an observed…
  • 2019 American Transplant Congress

    Safety and Efficacy of Anti Xa Inhibitors Post-Transplant with Concomitant Calcineurin Inhibitors

    K. A. McMurry1, J. Shuster2, K. Bain2, T. Horwedel3, J. Hartupee2

    1Michigan Medicine, Ann Arbor, MI, 2Barnes-Jewish Hospital, St. Louis, MO, 3Veloxis Pharmaceuticals, Cary, NC

    *Purpose: Despite demonstrated benefits of Anti-Xa Inhibitors (ATIs) in the general population, ATIs have not gained uniform acceptance in SOT due to lack of supportive…
  • 2019 American Transplant Congress

    Apixaban Therapy Is Safe And Effective In Most Organ Transplant Populations

    A. Brown, S. Palkimas, W. Ally

    University of Virginia Health System, Charlottesville, VA

    *Purpose: The bleed rates from the apixaban pivotal trial were 12.1% for non-major and 3.8% major bleeds. However outcomes in transplant recipients are less defined,…
  • 2019 American Transplant Congress

    Anti-Xa Level Monitoring for Treatment Dose Enoxaparin in Liver/Intestine Transplant Recipients

    J. Sullivan, J. Jebrock, J. Revollo, M. Perez, J. Garcia, T. Beduschi

    Jackson Memorial Hospital, Miami, FL

    *Purpose: Evaluate the use of anti-Xa levels in therapeutic enoxaparin dosing in liver/intestine transplant recipients.*Methods: A single-center retrospective chart review was conducted on liver/intestine transplant…
  • 2019 American Transplant Congress

    Direct Oral Anticoagulants: An Evaluation of the Safety and Efficacy in Solid Organ Transplant Recipients

    T. Pasley, A. Logan, A. Brueckner, L. Bowman, A. Silverman, A. Rumore

    Tampa General Hospital, Tampa, FL

    *Purpose: The use of direct oral anticoagulants (DOACs) has not been fully adopted by the solid organ transplant (SOT) community due to factors including, fluctuating…
  • 2019 American Transplant Congress

    The Comparative Safety and Efficacy of Direct Acting Oral Anticoagulants Relative to Warfarin Following Liver Transplantation

    A. Santeusanio, A. Weinberg, T. Schiano

    Mount Sinai Hospital, New York, NY

    *Purpose: This study describes the comparative safety and efficacy of direct acting oral anticoagulants (DOACs) relative to warfarin following liver transplantation, at a large academic…
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