2015 American Transplant Congress
Structural and Functional Basis for Non-HLA Antibody Mediated AT1R Activation
Nephrology and Intensive Care Medicine, Charité University Hospital, Berlin, Germany.
Angiotensin II type receptor (AT1R), a heptahelical protein signals stimuli upon binding of natural peptide ligand angiotensin II (Ang II) and the pathogenic non-HLA IgG…2015 American Transplant Congress
Is Pretransplant Anti-A/B Antibody Removal Prerequisite for Successful ABO Incompatible Kidney Transplantation in Children?
Purpose: We have recently demonstrated that the long-term outcome of ABO incompatible living donor kidney transplantation (ABOiKT) in children was comparable to those of ABO…2015 American Transplant Congress
Antibody Response Following Influenza Vaccination in Renal Transplant Recipients
Indiana University School of Medicne-IU Health, Indianapolis, IN.
Purpose: Following the recommended consensus guidelines of ATC for vaccination, at our institution we recommend annual vaccination for influenza + H1N1 (Flu) for renal transplant…2015 American Transplant Congress
Angiotensin Receptor Antibody IgG1 Subclass Predicts Accelerated Graft Loss in Those Kidney Transplant Recipients Who Develop Biopsy Proven Transplant Glomerulopathy Irrespective of the Presence Or Absence of Donor Specific Anti HLA Antibodies
We assessed the presence or absence of angiotensin receptor antibodies (ATRab) in all those Kidney Transplant Patients who have had biopsy proven transplant glomerulopathy (TG)…2015 American Transplant Congress
Molecular Testing for Microcirculation Injury Enhances the Assessment of Antibody-Mediated Rejection in Human Cardiac Allograft Biopsies
BACKGROUND: Despite continuous attempts to refine diagnostic consensus, accurate assessment of Antibody-mediated rejection (AMR) is an ongoing unmet need. The microcirculation represents the primary target…2015 American Transplant Congress
Outcomes of ABO Incompatible Kidney Transplantation in Children
Purpose: ABO blood group incompatible transplantation (ABOi) has become increasingly common over the last decade, in part due to a shortage of suitable deceased donor…2015 American Transplant Congress
Costimulation Blockade and Bortezomib to Desensitize Rhesus Macaque and Prolong Renal Allograft Survival
Surgery, Emory Transplant Center, Atlanta, GA.
[Background] Preformed donor specific antibody (DSA) due to prior sensitization affects a significant population of transplant patients, portending a poorer prognosis in short- and long-term…2015 American Transplant Congress
Outcomes of Treatment of Late Antibody-Mediated Rejection in Primary Renal Transplant Recipients – A Single Center Experience
Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.
Background: Successful reversal of early post-transplant antibody mediated rejection (AMR) is well documented, but data on the results of treatment of late AMR are lacking.…2015 American Transplant Congress
Use of RNA Sequencing for Discovery of Markers of Accommodation in Surveillance Biopsies from Recipients of an ABO-Incompatible Renal Transplant
Recipients of an ABO incompatible transplant have circulating anti-AB antibodies, A and/or B antigens expressed on endothelium and usually C4d deposition on the endothelium, yet…2015 American Transplant Congress
The Use of Eculizumab to Treat the Highly Sensitized Patient Awaiting Heart Transplant
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Highly sensitized patients (pts) awaiting heart transplantation remain a significant challenge due to prolonged often prohibitive wait times for suitable organs and increased rejection…
American Transplant Congress abstracts