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Articles tagged "Allocation"

  • 2017 American Transplant Congress

    Kidney Allograft Offers: Predictors of Turndown and the Relationship of Organ Acceptance Sequence to Kidney Allograft Survival.

    J. Cohen,1,2 J. Shults,2 D. Goldberg,2,3 D. Sawinski,1 P. Abt,4 P. Reese.1,2

    1Renal Division, University of Pennsylvania, Philadelphia, PA; 2Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA; 3Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; 4Transplant Surgery, University of Pennsylvania, Philadelphia, PA

    Background: There is growing interest in understanding patterns of organ acceptance and reducing organ discard. Little is known about how donor factors, holidays, and location…
  • 2017 American Transplant Congress

    Lung Transplant Recipient Travel Distance to Transplant Center Does Not Impact Survival.

    W. Tsuang,1 S. Lin,2 J. Schold,2 M. Valapour.1

    1Respiratory Institute, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH

    Purpose: We examined if the geographic distance recipients travel for lung transplant care impacts posttransplant survival at our center.Methods: Retrospective single center cohort study of…
  • 2017 American Transplant Congress

    Exception Scores for Patients on the Liver Waiting List.

    T. Weaver,1 D. Schladt,1 M. Skeans,1 J. Pyke,1 J. Zeglin,1 S. Leppke,1 A. Israni,1,2 B. Kasiske,1,2 W. Kim,3 J. Lake.4

    1Scientific Registry of Transplant Recipients, Minneapolis, MN; 2Hennepin County Medical Center, Minneapolis, MN; 3Stanford University, Stanford, CA; 4University of Minnesota, Minneapolis, MN

    Liver waitlist candidates are prioritized for allocation using model for end-stage liver disease (MELD) scores, and some patients receive higher MELD scores through exception. The…
  • 2017 American Transplant Congress

    Geographic Disparity in Kidney Transplantation After KAS.

    S. Zhou,1 A. Massie,1 X. Luo,1 E. Chow,1 S. Bae,1 S. Gentry,2 S. Gustafson,3 A. Wey,3 B. Thompson,3 N. Salkowski,3 J. Snyder,3 D. Segev.1

    1JHU, Baltimore; 2USNA, Annapolis; 3CDRG, Minneapolis

    The Kidney Allocation System (KAS), implemented in 12/2014, increased regional and national sharing of kidneys. Ideally, broader sharing would also reduce some of the stark…
  • 2017 American Transplant Congress

    Donor Recipient Matching Based on HLA Epitopes Improves Outcome in Kidney Transplant Recipients.

    O. Staeck,1 M. Niemann,3 F. Halleck,1 D. Khadzhynov,1 C. Schönemann,2 P. Reinke,1 E. Spierings,4 K. Budde,1 N. Lachmann.2

    1Nephrology, Charité Universitaetsmedizin, Berlin, Germany; 2HLA Laboratory, Charité Universitaetsmedizin, Berlin, Germany; 3PIRCHE, Berlin, Germany; 4Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands

    Background: HLA mismatches of the donor and recipient causing de novo donor-specific HLA antibodies (dnDSA) are a risk factor for immunologic complications and poor graft…
  • 2017 American Transplant Congress

    A Multistate Modeling Analysis of Time-Varying CPRA States and Its Impact on Kidney Transplant: A Focus on KAS Implementation.

    S. Kulkarni,1 I. Hall,2 R. Formica,1 D. Stewart,3 E. Greene,4 Y. Deng.4

    1Surgery & Medicine, Yale School of Medicine, New Haven, CT; 2Medicine, Utah School of Medicine, Salt Lake City, UT; 3United Network of Organ Sharing, Richmond, VA; 4Center for Analytical Sciences, Yale School of Public Health, New Haven, CT

    Background: Highly sensitized kidney transplant candidates are at higher risk of death on the waiting list(WL). OPTN policy change 8(Kidney Allocation System(KAS)) aimed to improve…
  • 2017 American Transplant Congress

    False-Positive Flow Cytometric Crossmatch Results and the Utility of the Virtual Crossmatch.

    N. Brown, J. Xin, J. Weidner, R. Upchurch, S. Marino.

    Pathology, University of Chicago Medicine, Chicago, IL

    Introduction: A negative crossmatch (XM) is critical for solid organ allocation. Flow cytometric XM (FCXM) is more sensitive than complement-dependent cytotoxicity XM (CDC-XM), and has…
  • 2017 American Transplant Congress

    Pancreas Organ Underutilization: 15-Year Analysis.

    S. Siddiqi, J. Almario, K. Villaroel-Gomez, J. Yoo, C. Blackburn, R. Batra, D. DiSabato, A. Lu, S. Akkina, A. Desai, R. Garcia-Roca.

    Department of Surgery, Loyola University Medical Center, Maywood, IL

    Pancreas recovery has declined by 32% over 15yrs. We analyzed national pancreas utilization rates for donors with suitable criteria for pancreas retrieval to understand this…
  • 2017 American Transplant Congress

    Waitlist Desensitization and the Rate of Deceased Donor Kidney Transplantation After Implementation of the Kidney Allocation System.

    E. Huang, S. Jordan, R. Najjar, J. Choi, A. Peng, A. Vo.

    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA

    Background:At Cedars Sinai Medical Center (CSMC), candidates with calculated panel reactive antibodies (cPRA) ≥30% (based on unacceptable antigens with MFI≥15,000) are desensitized while awaiting transplant.…
  • 2017 American Transplant Congress

    Improved Outcome of Kidney Transplants by Donor Recipient Matching Based on Predicted Indirectly Recognizable HLA Epitopes.

    O. Staeck,1 M. Niemann,4 F. Halleck,1 D. Khadzhynov,1 C. Schönemann,2 P. Reinke,1 E. Spierings,3 K. Budde,1 N. Lachmann.2

    1Nephrology, Charité Universitaetsmedizin, Berlin, Germany; 2HLA Laboratory, Charité Universitaetsmedizin, Berlin, Germany; 3Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands; 4PIRCHE, Berlin, Germany

    Introduction: De novo donor-specific HLA antibodies (dnDSA) are recognized as a risk factor for graft loss. Determinants of DSA specificity are generated via the indirect…
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