ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Articles tagged "Alloantigens"

  • 2022 American Transplant Congress

    Fibroblastic Reticular Cell Subset Transcriptional Reprogramming Differs in Response to Immunity versus Tolerance

    L. Li1, Y. Song1, M. Shirkey1, A. Kensiski1, W. Piao1, V. Saxena1, S. Gavzy1, B. Ma1, R. Abdi2, J. Bromberg1

    1UMB, Baltimore, MD, 2Harvard University, Boston, MD

    *Purpose: Lymph node (LN) fibroblastic reticular cells (FRCs) are central contributors to the LN niche. We hypothesized that FRC subsets reactive to immunity versus tolerance…
  • 2022 American Transplant Congress

    cDC1-Mediated Prolongation of Cardiac Allograft Survival and Alloantigen Induced Transcriptional Programming

    S. L. Schroth, E. B. Thorp

    Pathology, Northwestern Feinberg School of Medicine, Chicago, IL

    *Purpose: Heart transplantation is currently the only treatment for advanced stage heart failure. While patient survival after transplantation has improved acutely, the same cannot be…
  • 2022 American Transplant Congress

    Identification of a Human B Cell State with Allogeneic Antigen Cross-Presenting Potential

    U. Bhatia, E. C. Guinan

    Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA

    *Purpose: B cells are known to play a significant role in allograft tolerance or rejection, largely determined by production of cytokines and antibodies that suppress…
  • 2022 American Transplant Congress

    Impact of the High Baseline Anti-a/b Antibody Titer on the Clinical Outcomes in ABO-incompatible Living Donor Liver Transplantation

    J. Cho, B. Lee, H. Lee

    Surgery, Seoul National Bundang Hospital, Seongnam, Korea, Republic of

    *Purpose: Recently, advances in desensitization protocol have made ABO-incompatible (ABOi) living donor liver transplantation (LDLT) feasible option in the era of organ shortage. Although, multiple…
  • 2022 American Transplant Congress

    Optimal Development and Effector Function of Antibody-Suppressor CXCR5+CD8+ T Cells Requires Host IFN-γ and CD4+ T Cells

    J. Zimmerer, S. Chaudhari, M. Hart, J. Han, K. Koneru, G. Bumgardner

    OSUWMC, Columbus, OH

    *Purpose: We reported the discovery of a novel subset of CXCR5+IFNγ+CD8+ T cells that suppresses antibody production (CD8+ TAb-supp cells). Alloprimed CD8+ TAb-supp cells significantly…
  • 2022 American Transplant Congress

    Marginal Zone Phenotype B Cells Are Required for Formation of Donor-Specific IgG After Allogeneic Sensitization

    M. A. Kallarakal, G. Cohen, S. M. Krummey

    Department of Pathology, Johns Hopkins University, Baltimore, MD

    *Purpose: The formation of allogeneic antibody directed against non-self MHC, termed donor-specific antibody (DSA), is a significant barrier to successful transplant outcomes. Pre-formed DSA limits…
  • 2022 American Transplant Congress

    Alloprimed Antibody-Suppressor CD8+ T Cells Preferentially Kill Alloprimed Germinal Center B Cells

    J. Zimmerer, S. Chaudhari, G. Bumgardner

    OSUWMC, Columbus, OH

    *Purpose: Antibody-mediated rejection (AMR) is a significant contributor to transplant rejection. Our prior work identified a novel subset of CXCR5+CD8+ T cells (CD8+ TAb-supp cells)…
  • 2022 American Transplant Congress

    Exosomal TGFbeta:LAP as Immunosuppressive Mediator of Allo-Tolerance

    W. Burlingham1, E. Jankowska-Gan2, J. Fechner3, C. Little2, J. Sullivan4, D. Foley1

    1University of Wisconsin, Madison, WI, 2Surgery-Transplant Division, University of Wisconsin, Madison, WI, 3Surgery-Transplant Division, University of Wisconsin-Madison, Madison, WI, 4Surgery, University of Wisconsin, Madison, WI

    *Purpose: TGFβ has long been known as a key component in tolerance mediated by Treg cells. Here we show that, unlike IL10, but like CD39/CD73,…
  • 2022 American Transplant Congress

    Reduced CD45RA-CCR7- Tregs Subtypes in Highly Sensitised Patients Associates with a Failure to Regulate Memory IFNγ Production in Response to Donor Alloantigens

    C. Dudreuilh1, S. Basu1, O. Shaw2, H. Burton1, C. Domingo-Vila1, T. Tree1, G. Lombardi1, C. Scotta1, A. Dorling1

    1King's College London, London, United Kingdom, 2Viapath Clinical Transplantation Laboratory, Guy's Hospital, London, United Kingdom

    *Purpose: Highly sensitised (HS) patients exhibit worse long-term outcomes after kidney transplantation compared to non-sensitised patients. It has been hypothesised that regulatory T cells (Tregs)…
  • 2022 American Transplant Congress

    Regulatory T Cells Suppress Memory IFN-Gamma Production in Highly Sensitised Patients

    C. Dudreuilh1, S. Basu1, O. Shaw2, H. Burton1, C. Domingo-Vila1, T. Tree1, G. Lombardi1, C. Scotta1, A. Dorling1

    1King's College London, London, United Kingdom, 2Viapath Clinical Transplantation Laboratory, Guy's Hospital, London, United Kingdom

    *Purpose: Highly sensitized patients (HS) present worse long-term outcome after transplantation compared to those without donor-specific antibodies (DSA). It has been suggested that desensitisation using…
  • 1
  • 2
  • 3
  • …
  • 8
  • Next Page »

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2023 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences