2020 American Transplant Congress
Roles of Calpastatin in Ischemia/Reperfusion Injury in Aged Livers
Surgery, Washington University St. Louis, St. Louis, MO
*Purpose: Aged livers are far more susceptible to ischemia/reperfusion (I/R) injury than young livers. No therapeutic strategies are available to reduce I/R injury in elderly…2020 American Transplant Congress
A Simple Scoring System for Risk Stratification in Liver Transplantation after Donor Liver Biopsy
Surgery, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA
*Purpose: Macrosteatosis (MaS) identified on donor liver biopsy (DLBx) influences organ utilization but alone is not predictive of outcomes following liver transplantation (LT). Here we…2020 American Transplant Congress
Factors Influencing Background Cell-Free DNA Levels: Implications for Donor-Derived Cell-Free DNA Assessment in Transplant Patients
*Purpose: Detecting elevated levels of donor-derived cell-free DNA (dd-cfDNA) in the plasma of transplant recipients has been used as a metric to determine graft injury…2020 American Transplant Congress
Liver Transplant Outcomes Across the Age Distribution and Interactions with County Health
*Purpose: We examined risk of graft failure and patient mortality after liver transplant (LT) across the age continuum and county Health Outcomes & Health Factors…2020 American Transplant Congress
From Marginal to Meaningful: Donor Liver Biopsy Increases Donation Rates amongst Elderly Donors
*Purpose: Recently, there has been public scrutiny on the non-utilization of elderly donors in liver transplantation. Here, we evaluate the influence of donor liver biopsy…2020 American Transplant Congress
Older Organs Transfer Senescence to Transplant Recipients
1Brigham and Women's Hospital, Boston, MA, 2Mayo Clinic, Rochester, MN
*Purpose: Older organs represent an underutilized potential. Organ age, at the same time, augments alloimmune responses resulting into increased acute rejection rates. Senescent cells accumulate…2020 American Transplant Congress
Improving Eligibility of Renal Transplants in the Elderly
*Purpose: In the recent past, older age was a contraindication to kidney transplantation (KT). New kidney allocation schemes with use of longevity matching, initiation of…2020 American Transplant Congress
Association between Pre-Transplant Frailty and Increased Length of Stay after Lung Transplantation
David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: Given the growing numbers of older lung transplant candidates, there has been increasing interest in using frailty assessment for risk stratification of transplant candidates.…2020 American Transplant Congress
History of Coronary Artery Disease Predicts Inferior Survival in Liver Transplant Recipients of Advanced Age in a Large Multicenter U.S. Cohort
*Purpose: Coronary artery disease (CAD) is common in patients of advanced age and does not preclude liver transplantation (LT) if adequately treated. We aimed to…2020 American Transplant Congress
Results of Pancreas Transplantation in Diabetic Patients with End-Stage Kidney Disease Older Than 50 Years
*Purpose: Improvement of care in type 1 diabetes mellitus, with the optimization of patient access to insulins of variable action, has led to macro- and…
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