Articles tagged "Age factors"

2020 American Transplant Congress
T Cell Hyporesponsiveness in Kidney Transplant Recipients is Associated with Urinary Tract Infections and Age of Kidney Transplant: Implications for Allograft Nephropathy
A. Assounga, S. Omarjee
Dept of Nephrology, University of KwaZulu-Natal, Durban, South Africa
*Purpose: Chronic allograft nephropathy is the main cause of kidney graft loss. With the use of potent immunosuppressive treatments, acute rejections are less and less…
2020 American Transplant Congress
Donor and Recipient Sex Affect Transplant Outcomes in an Age-Specific Fashion
R. Maenosono¹, Y. Nian¹, J. Iske¹, Y. Liu¹, H. Azuma², E. Milford³, S. G. Tullius¹
¹Division of Transplant Surgery, Brigham and Women's Hospital, Boston, MA, ²Urology, Osaka Medical College, Osaka, Japan, ³Renal Division, Brigham and Women's Hospital, Boston, MA
*Purpose: Donor and recipient sex impact transplant outcomes. The biology of sex-specific alloimmune responses has not been studied in detail.*Methods: Using clinical data from more…
2020 American Transplant Congress
Targeting CD4⁺ T Cell Metabolism Prolongs Graft Survival Age-Specifically
Y. Nian, J. Iske, K. Minami, R. Maenosono, T. Heinbokel, A. Elkhal, S. G. Tullius
Division of Transplant Surgery and Transplant Surgery Research Laboratory, Harvard Medical School, Boston, MA
*Purpose: If and how aging affects T-cell metabolism and alloimmune response is unclear. Here, we show that T-cell metabolism changes drastically in aging. Most notably,…
2020 American Transplant Congress
Serum αKlotho after Living Kidney Donation: A Systematic Review and Meta-Analysis
W. Cheungpasitporn¹, C. Thongprayoon², N. Leeaphorn³, M. A. Mao⁴, J. A. Neyra⁵
¹Nephrology, University of Mississippi Medical Center, Jackson, MS, ²Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ³Renal Transplant Program, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO, ⁴Nephrology and Hypertension, Mayo Clinic, Jacksonville, FL, ⁵Nephrology, University of Kentucky, Lexington, KY
*Purpose: αKlotho (klotho) is a known anti-aging protein that exerts diverse physiological effects. Defect in klotho gene expression in mice can result in a syndrome…
2020 American Transplant Congress
Older Livers Should Not Be Utilized in Pediatric Liver Transplantation
M. MacConmara, C. Feizpour, A. Aqul, D. Desai, P. Vagefi, S. Hanish, L. DeGregorio, C. S. Hwang
UT Southwestern, Dallas, TX
*Purpose: Organ scarcity in liver transplantation has required expansion of the acceptable criteria used for donor selection. The utilization of older donors (>60 years) has…
2020 American Transplant Congress
Evaluation of Infectious and Malignant Complications in Elderly Renal Transplant Recipients Receiving Alemtuzumab Compared to Basiliximab
K. Lang¹, J. Shulte¹, K. Cunningham¹, C. D'Agostino¹, M. Kapugi¹, C. Kane¹, A. Novak¹, J. Leventhal²
¹Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, ²Division of Transplant Surgery, Northwestern Memorial Hospital, Chicago, IL
*Purpose: The choice of induction immunosuppression can affect several outcomes after kidney transplant (KTx), especially for elderly recipients. For this population, there is limited data…
2020 American Transplant Congress
Patient and Kidney Allograft Outcomes in Septuagenarians – A Single Center Experience
G. Katz-Greenberg, A. Yadav, M. P. Martinez-Cantarin, P. Singh
Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, PA
*Purpose: Based on Scientific Registry of Transplant Recipients reporting, the proportion of patients 65 years or older on the kidney transplant (KT) waiting list has…
2020 American Transplant Congress
Pancreas Transplant in Patients Older Than 50: An Analysis of Outcomes and Immunosuppression
I. Booth¹, J. Casale¹, S. Freedman¹, B. Ravichandran¹, J. Scalea², A. Haririan², B. Masters¹
¹Pharmacy, University of Maryland Medical Center, Baltimore, MD, ²Medicine, University of Maryland Medical Center, Baltimore, MD
*Purpose: Pancreas transplant (PT) is the ideal therapy for many patients with diabetes and kidney failure. There are limited published data addressing the impact of…
2020 American Transplant Congress
A Multi-Center Pilot and Feasibility Randomized Clinical Trial of a Home-Based Exercise Program for Patients with Cirrhosis: The Strength Training Intervention
J. C. Lai¹, M. R. Kappus², J. L. Dodge¹, R. Wong¹, Y. Mohamad¹, D. L. Segev³, M. A. McAdams-DeMarco⁴
¹University of California, San Francisco, San Francisco, CA, ²Duke University, San Francisco, NC, ³Johns Hopkins Medical Institute, Baltimore, MD, ⁴Johns Hopkins School of Public Health, Baltimore, MD
*Purpose: Patients with cirrhosis experience progressive physical frailty and functional decline that may ultimately lead to an increased risk of death. We developed the Strength…
2020 American Transplant Congress
Outcomes after Declining Offers from Older Donor Kidneys for Kidney Transplant Candidates
J. D. Motter, L. Liyanage, K. R. Jackson, M. G. Bowring, T. Ishaque, Y. Yu, S. Yu, J. M. Garonzik-Wang, A. B. Massie, D. L. Segev
Johns Hopkins University, Baltimore, MD
*Purpose: Older donor kidneys (ODKs) are often declined as they are associated with higher post-transplant mortality and graft loss, yet those who decline may wait…

« Previous Page
1
…
4
5
6
7
8
…
24
Next Page »