ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Age factors"

  • 2020 American Transplant Congress

    A Multi-Center Pilot and Feasibility Randomized Clinical Trial of a Home-Based Exercise Program for Patients with Cirrhosis: The Strength Training Intervention

    J. C. Lai1, M. R. Kappus2, J. L. Dodge1, R. Wong1, Y. Mohamad1, D. L. Segev3, M. A. McAdams-DeMarco4

    1University of California, San Francisco, San Francisco, CA, 2Duke University, San Francisco, NC, 3Johns Hopkins Medical Institute, Baltimore, MD, 4Johns Hopkins School of Public Health, Baltimore, MD

    *Purpose: Patients with cirrhosis experience progressive physical frailty and functional decline that may ultimately lead to an increased risk of death. We developed the Strength…
  • 2020 American Transplant Congress

    Outcomes after Declining Offers from Older Donor Kidneys for Kidney Transplant Candidates

    J. D. Motter, L. Liyanage, K. R. Jackson, M. G. Bowring, T. Ishaque, Y. Yu, S. Yu, J. M. Garonzik-Wang, A. B. Massie, D. L. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Older donor kidneys (ODKs) are often declined as they are associated with higher post-transplant mortality and graft loss, yet those who decline may wait…
  • 2020 American Transplant Congress

    Effect of Increased Recipient Age on Solid-Organ Pancreas Transplantation Outcomes: A Systematic Review

    J. E. Ling

    Nephrology, Monash Medical Centre, Clayton, Australia

    *Purpose: Increased recipient age has been associated with poorer solid organ pancreas transplant (SOPTx) outcomes. We hypothesized that recipient age cut-offs in Australia and New…
  • 2020 American Transplant Congress

    Extracellular Vesicles Mediate Endothelial to Mesenchymal Transition and Tubular Senescence in Renal Antibody- Mediated Rejection by Inducing Complement Activation

    G. Castellano, R. Franzin, A. Stasi, C. Divella, G. Merlotti, M. Quaglia, F. Sallustio, G. Stallone, V. Cantaluppi, L. Gesualdo

    Emergency and Organ Transplantation, University of Bari, Bari, Italy

    *Purpose: EVs (Extracellular vesicles), circulating microparticles able to mediate cell-to cell communication, are emerging as pivotal in different kidney diseases. Renal Antibody-Mediated Rejection (AMR) is…
  • 2020 American Transplant Congress

    Dual Kidney Transplantation Offers a Safe and Effective Way to Use Kidneys from Deceased Donors Older Than 70 Years

    K. Lee, J. Park, S. Cha, M. Kim

    Samsung Medical Center, Seoul, Korea, Republic of

    *Purpose: Dual kidney transplantation (DKT) offers a way to extend the use of kidneys from expanded criteria donors (ECDs). Here, we compared the outcomes of…
  • 2020 American Transplant Congress

    Association between Sarcopenia and Nutritional Factors in Kidney Transplant Recipients

    A. Kosoku1, J. Uchida1, T. Ishihara2, T. Iwai1, H. Shimada1, K. Kabei1, S. Nishide1, T. Naganuma1, T. Nakatani1

    1Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, 2Innovative and Clinical Research Promotion Center, Gifu University Hospital, Gihu, Japan

    *Purpose: Malnutrition is an important risk factor for the development of sarcopenia. Several methods are used for the assessment of nutritional status including serum albumin…
  • 2020 American Transplant Congress

    Characteristics of Anonymous Living Donors and Their Recipients. Appropriate Use of a Rare and Valuable Gift

    A. Sharfuddin, M. Panezai, M. Yaqub, D. Mishler, O. Adebiyi, T. Taber

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Anonymous Living Donors are a special select set of donors. As there continues to be advances in Paired Donation, we review the trends and…
  • 2020 American Transplant Congress

    Multi-National Survey among Nephrologists and Transplant Surgeons About the Suitability and Acceptance of the Marginal Live Kidney Donors Regarding Age Discrepancy

    Z. Arabi1, S. Kaysi2, A. Hamad3, M. Bukhari4, A. Mateen1, E. Elhassan1, A. Altheaby1

    1KAMC, Riyadh, Saudi Arabia, 2CHR Orleans, Orleans, France, 3The Regional Medical Center, Orangeburg, SC, 4Taif University, Taif, Saudi Arabia

    *Purpose: Living donor kidney transplantation is the best option for patients on dialysis. There are no guidelines or generally accepted consensus about the acceptable kidney…
  • 2020 American Transplant Congress

    Aging Aggravated Liver Ischemia and Reperfusion Injury by Promoting Sting-Mediated NLRP3 Activation in Macrophages

    Z. Rao, W. Zhong, H. Zhou, P. Wang, X. Wang, L. Lu

    The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: Aggravated liver injury and enhanced intrahepatic inflammation was found in old livers post ischemia and reperfusion (IR). However, the function and underlying mechanism of…
  • 2020 American Transplant Congress

    Age-Enhanced Transplant Vasculopathy Associates with Impaired Vascular Mitophagy

    M. Blin1, D. Tyrrell1, S. Wood1, D. Farris1, S. G. Tullius2, D. R. Goldstein1

    1Micro and Immunology/Internal Medicine, University of Michigan, Ann Arbor, MI, 2Transplant Surgery, Brigham and Women's Hospital, Boston, MA

    *Purpose: Donor aging leads to increased chronic allograft vasculopathy (CAV) for unclear reasons. Here, we investigated whether impaired alterations in mitophagy, a mechanism to remove…
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