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Articles tagged "Age factors"

  • 2016 American Transplant Congress

    Profiling Immunologic Risk for Acute Rejection in Liver Transplantation: Recipient Age Is a Robust Risk Factor.

    M. Kueht, R. Cotton, C. O'Mahony, J. Goss, A. Rana.

    Surgery, Division of Abdominal Transplantation and Hepatobiliary Surgery, Balyor College of Medicine, Houston, TX.

    Profiling the immunologic risk for acute rejection in liver transplantation (OLT) may allow for selection immunosuppression (IS) target ranges appropriate to risk levels, all with…
  • 2016 American Transplant Congress

    Watch Out for the Guy with the Low EPTS Score: Nonadherence and Kidney Allograft Failure.

    A. Liu, K. Balabhadrapatruni, J. Augustine.

    Medicine, University Hospitals Case Medical School, Cleveland, OH.

    Background: Nonadherence is a known cause of rejection and kidney allograft failure. Our aim was to define risk factors for allograft loss related to nonadherence.…
  • 2016 American Transplant Congress

    Survival After Second Kidney Transplant: Are We Being Good Stewards?

    C. Jay, J. Pugh, G. Halff, G. Abrahamian, F. Cigarroa, N. Stephens, K. Washburn.

    University of Texas Health Science Center, San Antonio.

    BACKGROUND: Primary kidney transplant is associated with increased life years compared with dialysis. Comparable patient survival between primary (1KT) and second kidney transplants (2KT) has…
  • 2016 American Transplant Congress

    Pediatric En Bloc Kidney Transplants Reduce DGF and Are Misrepresented by the KDPI.

    M. Khan,1 H. El-Hennawy,1 A. Farney,1 J. Rogers,1 G. Orlando,1 A. Reeves-Daniel,2 A. Palanisamy,2 M. Gautreaux,3 S. Iskandar,3 W. Doares,4 S. Kaczmorski,4 R. Stratta.1

    1Surgery, Wake Forest, Winston-Salem, NC; 2Internal Medicine, Wake Forest, Winston-Salem, NC; 3Pathology, Wake Forest, Winston-Salem, NC; 4Pharmacy, Wake Forest, Winston-Salem, NC.

    Controversy exists regarding optimal use of kidneys from small pediatric donors (SPDs). The study purpose was to compare outcomes between single and dual en bloc…
  • 2016 American Transplant Congress

    Young Recipients Receiving Kidneys from Older Donors Have Poorer Allograft Outcomes.

    A. Wardle, M. Willicombe, D. Goodall, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Introduction: An increasing number of marginal donors are being used in order to expand the donor pool. Age is one of the major criteria in…
  • 2016 American Transplant Congress

    15-Years Experience with the EUROTRANSPLANT Senior Program.

    H.-M. Tautenhahn,1 S. Brückner,1 H.-M. Hau,1 H. Morgül,1 J. Broschewitz,1 C. Pipiale,1 F. Pankow,1 S. Erler,2 M. Bartels.1

    1Universitätsklinikum Leipzig, Leipzig, Germany; 2Martin-Luther-Universität Halle, Halle, Germany.

    Introduction: The ESP (Eurotransplant senior program), introduced in 1999 by EUROTRANSPLANT, is supposed to shorten the waiting period for elder recipients. The aim of this…
  • 2016 American Transplant Congress

    Replicative Senescence and Arteriosclerosis After Kidney Transplantation.

    K. De Vusser,1 D. Martens,2 E. Lerut,3 D. Kuypers,1 T. Nawrot,2 M. Naesens.1

    1Department of Nephrology and Renal Transplantation, UZ Leuven, Leuven, Belgium; 2Department of Imaging and Pathology, KULeuven, Leuven, Belgium; 3Centre for Environmental Sciences, U Hasselt, Hasselt, Belgium.

    BackgroundReplicative senescence is associated with telomere shortening. In native kidneys, obtained prior to transplantation, we recently described and validated a significant association between shorter intrarenal…
  • 2016 American Transplant Congress

    Defining Frailty in Liver Transplant Recipients.

    L. Louwers,1 K. Eid,1 J. Plescia,1 N. Presser,1 J. Muntean,1 M. Kattan,2 K. Chagrin,2 C. Miller,1 D. Kelly.1

    1Surgery, Cleveland Clinic, Cleveland, OH; 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

    PURPOSETo define frailty in the liver transplant (OLT) population to optimize care and assist in predicting post OLT outcomes.METHODSAll adult primary OLT patients from 01/2010…
  • 2016 American Transplant Congress

    Induction Agent Use and Outcomes in Older KT Recipients: Patient and Center Level Associations.

    M. McAdams-DeMarco, Q. Huang, X. Luo, B. Orandi, S. Dorry.

    Johns Hopkins, Baltimore.

    Background: Clinical trials of induction agents typically exclude older recipients, so our practice in older recipients is extrapolated from this. Older adults are different, so…
  • 2016 American Transplant Congress

    C1-Inhibitor Abrogated Ischemia/Reperfusion (I/R) Induced Inflammaging by Inhibiting Senescence-Associated Secretory Phenotype (SASP) in Tubular Epithelial Cells (TEC).

    G. Castellano,1 R. Franzin,1 A. Stasi,1 C. Divella,1 M. Gigante,1 S. Simone,1 A. Intini,1 A. Picerno,1 P. Pontrelli,1 A. Crovace,1 M. Battaglia,1 B. Oortwijn,2 E. Amersfoort,2 G. Grandaliano,3 L. Gesualdo.1

    1Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy; 2Pharming Technologies, Leiden, Netherlands; 3Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.

    Inflammaging is a pathogenic process usually associated with chronic kidney disease such as diabetic nephropathy where TEC cells have a diminished regenerative potential and develop…
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