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Articles tagged "Age factors"

  • 2018 American Transplant Congress

    Autophagy Impacts Specificity and Characteristics of Innate Alloimmune Responses in Aging

    T. Heinbokel, K. Minami, Y. Nian, A. Elkhal, S. Tullius.

    Transplant Surgery Research Lab, Brigham and Women's Hospital, Boston, MA.

    Aging and chronic antigen exposure shape the balance of innate and adaptive immunity. We hypothesized that autophagy will impact the homeostasis of innate and adaptive…
  • 2018 American Transplant Congress

    Transplant Trends in Young Adults: Silent Alcohol Epidemic

    N. Kemmer,2 N. Bozanich,1 S. Agrawal,2 C. Albers,2 R. Syed,2 A. Alsina.2

    1Gastroenterology, USF, Tampa; 2Transplant Hepatology, Tampa General Medical Group, Tampa.

    With the introduction of effective antiviral therapy for HCV, there is a paradigm shift in liver disease with a decline in HCV but a parallel…
  • 2018 American Transplant Congress

    Liver Transplantation Using Pediatric versus Adult Donor Grafts in Adult Recipients

    Y. Tang, Q. Zhao, Z. Zhang, L. Wang, W. Ju, Z. Zhu, S. Huang, Z. Guo, X. He, G. Chen.

    Organ Transplant Center, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Background and Aim: The reported outcomes of adult liver transplantation using pediatric allografts are largely controversial based on single center studies. We aimed to compare…
  • 2018 American Transplant Congress

    Frailty and Kidney Transplantation: AST-KPCOP Survey of Center Practices

    M. McAdams DeMarco, S. Rasmussen, R. Parsons, T. Alhamad, K. Johansen, S. Tullius, R. Lynch, M. Harhay, M. Rao, J. Berger, J. Lappin, J. Tan, X. Cheng, K. Woodside, S. Parajuli, K. Lentine, B. Kaplan, D. Segev, J. Kobashigawa, D. Dadhania.

    Kidney Pancreas COP, AST, Mt. Laurel.

    Background: Frailty is a clinical phenotype of decreased physiologic reserve and resistance to stressors. Given the potential utility of frailty evaluation as prognosticator of kidney…
  • 2018 American Transplant Congress

    Multiple Factors Contribute to an Expanded Immune Risk Profile in Pre Renal Transplant Candidates

    D. DeWolfe,1 K. McGann,1 J. Ghofrani,1 E. Geiger,1 C. Helzer,1 S. Kleiboeker,2 S. Jost,1 C. Tan.1

    1Medicine, Beth Israel Deaconess Medical Center, Boston, MA; 2Viracor-Eurofins, Lee's Summmit, MO.

    Introduction: Older renal transplant recipients have a lower risk of rejection, but are at increased risk for infectious complications. An immune risk profile (IRP) has…
  • 2018 American Transplant Congress

    Medical Contraindications to Solid Organ Transplant Listing: A Survey of Heart, Liver, Lung and Kidney Programs

    A. Wall, G. Lee, J. Maldonado, D. Magnus.

    Stanford University, Palo Alto, CA.

    Purpose: The purpose of this study was to evaluate the influence of advanced age, obesity and HIV seropositivity on solid organ transplant listing across liver,…
  • 2018 American Transplant Congress

    What's Normal? An Evaluation of Pediatric T Cell Markers in Healthy Controls

    M. Sosniuk,1 A. Halpin,1,2,5,6,7 J. Wizniak,7 A. Szkotak,6,7 S. Urschel,1,2,5 L. Ionescu,1,2,5 L. West.1,2,3,4,5,6

    1Dept of Pediatrics, U of Alberta, Edmonton, Canada; 2Alberta Transplant Institute, Edmonton, Canada; 3Dept of MMI, U of Alberta, Edmonton, Canada; 4Dept of Surgery, U of Alberta, Edmonton, Canada; 5Canadian National Transplant Research Program, National, Canada; 6Dept of Laboratory Medicine, U of Alberta, Edmonton, Canada; 7Laboratory Medicine and Pathology, Alberta Health Services, Edmonton, Canada.

    INTRODUCTION: Studying pediatric patients includes challenges such as difficulty obtaining samples, limited normal controls and small volumes. Standardized flow cytometry (FC) lymphocyte immunophenotyping panels are…
  • 2018 American Transplant Congress

    Impact of Age and Race on BK Viremia among Kidney Transplant Recipients

    S. Mehta,1,3 N. Ali,1,3 B. Lonze,2,3 A. Stachel.3

    1Medicine, New York University School of Medicine, New York, NY; 2Surgery, New York University School of Medicine, New York, NY; 3NYU Langone Health, New York, NY.

    Background: Older age has been described as a potential risk factor for BK virus infection after kidney transplantation. The purpose of this study is to…
  • 2018 American Transplant Congress

    Early Infectious Outcomes of Older Adults Undergoing Kidney Transplantation (KT). A Case Control Study

    M. Hemmersbach-Miller,1,2 K. Schmader.3

    1Infectious Diseases, Duke University Medical Center, Durham, NC; 2Duke Clinical Research Institute, Durham, NC; 3Geriatrics, Duke University Medical Center, Durham, NC.

    Study Purpose: Our aim was to investigate if among older KT recipient, the types of infections, number of rejections, graft and patient survival in the…
  • 2018 American Transplant Congress

    Ethnic and Age Disparities in Outcomes among Liver Transplant Waitlist Candidates

    M. Mustian,1 S. Gray,1 B. Shelton,1 R. Reed,1 P. MacLennan,1 J. White,1 D. Eckhoff,1 R. Allman,2 J. Locke.1

    1University of Alabama at Birmingham, Birmingham; 2Department of Veterans Affairs, Washington DC.

    Background: Despite the increasing prevalence of end-stage liver disease (ESLD) in older adults, there is no consensus to determine suitability for liver transplantation (LT) in…
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