Articles tagged "Age factors"

2019 American Transplant Congress
Differential Impact of Donor and Recipient Age on Post-Lung Transplantation Outcomes
K. Patel¹, C. Li¹, C. Wallace¹, J. Kilkenny¹, D. P. Allen¹, S. Nadig¹, M. Goddard², C. Krieg¹, C. Atkinson¹
¹Surgery, Medical University of South Carolina, Charleston, SC, ²Pathology, Royal Papworth Hospital NHS Trust, C, SC
*Purpose: Donor and recipient age at the time of lung transplantation (LTx) have been implicated in poor patient outcomes. The underlying mechanisms driving these effects…
2019 American Transplant Congress
Post-Transplant Functional Status Trajectory among Adult Kidney Transplant Recipients
N. Chu, Z. Shi, H. Ying, C. Haugen, D. Segev, M. McAdams-DeMarco
Johns Hopkins University, Baltimore, MD
*Purpose: Frailty and disabilities are highly prevalent among kidney transplant (KT) recipients, but are not routinely measured in KT recipients. The Karnofsky Performance Scale (KPS)…
2019 American Transplant Congress
Clinical, Aging, Morphometric Measures & Adverse Outcomes in Kidney Transplant Recipients
A. Muzaale¹, N. Chu¹, H. Ying¹, B. Ross², D. Segev¹, M. McAdams-Demarco¹
¹JHU, Baltimore, MD, ²UM, Ann Habor, MI
*Purpose: Sarcopenia is a hallmark of frailty, a geriatric phenotype which is common among kidney transplant (KT) candidates and recipients. Sarcopenic-obesity is a high-risk state…
2019 American Transplant Congress
Development of a Recurrence Risk Score in IgA Nephropathy after Kidney Transplantation: Role of Recipient Age and HLA-B Mismatch
L. M. Rodas Marin¹, E. Ruiz², A. García³, M. Blasco¹, P. Ventura¹, E. de Soussa¹, O. Viñas⁴, F. Diekmann¹, L. Quintana¹
¹Nephrology and Renal Trasplantation, Hospital Clinic, Barcelona, Spain, ²Immunology, Hospital Clinic, Barcelona, Spain, ³Pathology, Hospital Clinic, Barcelona, Spain, ⁴Inmunology, Hospital Clinic, Barcelona, Spain
*Purpose: Recurrence of IgA nephropathy is an important and growing cause of kidney allograft dysfunction. The purpose of this observational retrospective study was to characterize…
2018 American Transplant Congress
Increased Length of Stay of the Donor Decreases Heart Transplant Recipient Survival
H. Copeland,¹ R. Talluri,² A. Panos,¹ R. Cochran,¹ L. Creswell,¹ D. Baran.³
¹Surgery, University of Mississippi Medical Center, Jackson, MS; ²Biostatistics, University of Mississippi Medical Center, Jackson, MS; ³Cardiology, Sentara Heart Hospital, Norfolk, VA.
Purpose: We hypothesize that the longer the cardiac donor is in the hospital prior to procurement, the worse the heart transplant (tx) recipient outcome for…
2018 American Transplant Congress
Recipient Outcomes in Age Mismatched Living Kidney Transplants from Donors > 60 Years: A UNOS Database Analysis
O. Adebiyi, A. Riaz, M. Yaqub, D. Mishler, T. Taber, A. Sharfuddin.
Indiana University, Indianapolis.
Background: Donor and recipient age mismatch kidney transplantation are known to affect graft survival. We examined the impact of age mismatching on graft survival after…
2018 American Transplant Congress
The Impact of Age-Matching on Graft Function and Graft Survival after Living Donor Kidney Transplantation
J. Lee,¹ D. Kim,¹ J. Lee,¹ J. Lee,¹ Y. Jung,¹ M. Ju,¹ S. Song,² J. Lee,³ K. Huh,¹ B. Kim,⁴ S. Kim,¹ Y. Kim,¹ M. Kim.¹
¹Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea; ²Department of Surgery, Ewha Womans University, School of Medicine, Seoul, Republic of Korea; ³Department of Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea; ⁴Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Introduction: To overcome the shortage of organs, the influence of age matching in living donor kidney transplantation should be studied. We analyzed the impact of…
2018 American Transplant Congress
Two Decades of Eurotransplant Senior Program (ESP): Time on Dialysis Independently Impacts Patient Survival, Allograft Survival and Quality of Life after Kidney Transplantation
T. Schachtner,^1,2,3 N. Otto,¹ P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charite Campus Virchow Clinic, Berlin, Germany; ³Berlin Institute of Health (BIH), Charite and Max Delbrueck Center, Berlin, Germany.
In 1999, the Eurotransplant Senior Program (ESP) was implemented and allocates kidneys from deceased-donors ≥65 years to kidney transplant recipients ≥65 years (ESP-KTRs). The ESP…
2018 American Transplant Congress
Multivariate Cox Proportional Hazards Model for Estimating Long-Term Risk of Aging Kidney Transplant Recipients
A. Yaldo, I. Bajjoka, X. Han, C. Crombez, M. Abouljoud.
Henry Ford Transplant Institute, Detroit, MI.
Purpose: The growing number of elderly kidney transplant recipients (KTR) presents an opportunity to analyze and predict long-term outcomes and risk in this aging population.Methods:…
2018 American Transplant Congress
Senolytic Drug Treatment Attenuates mtDNA-Mediated Inflammatory Injury in Old Donors and Prolongs Cardiac Allograft Survival
K. Minami,¹ M. Seyda,¹ T. Heinbokel,¹ Y. Nian,¹ M. Quante,¹ G. Liu,¹ R. Abdi,² T. Tchkonia,³ J. Kirkland,³ A. Elkhal,¹ S. Tullius.¹
¹Transplant Surgery Division, Department of Surgery, Brigham and Women's Hospital, Boston, MA; ²Transplantation Research Center, Brigham and Women's Hospital, Boston; ³Robert and Arlene Kogod Center on Aging, Mayo Clinic College of Medicine, Rochester, MN.
Introduction: Solid organ transplantation has seen a increase in the utilization of older organs. Here, we investigate how aging-associated kinetics of damage associated molecular patterns…