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Articles tagged "Adverse effects"

  • 2021 American Transplant Congress

    Evaluation of the Conversion from Tacrolimus to Sirolimus in Liver Transplant Recipients

    H. Bakhtiari1, S. Todd2, H. Snyder2, D. Lo2, M. Flynn2

    1Mercer University College of Pharmacy, Atlanta, GA, 2Emory University Hospital, Atlanta, GA

    *Purpose: The purpose of this study was to compare outcomes in liver transplant patients maintained on standard calcineurin inhibitor (CNI) therapy with tacrolimus versus those…
  • 2021 American Transplant Congress

    The Initial Impact of Covid-19 on Reported Graft Failure Rates and Potential Confounding of Srtr Psrs

    A. Wey1, J. Miller1, D. Musgrove1, Y. Ahn1, M. Valapour2, N. Salkowski1, M. Skeans1, A. Massie3, R. Hirose4, D. Segev3, A. Israni1, J. Snyder1, B. Kasiske1

    1SRTR, Minneapolis, MN, 2Cleveland Clinic, Cleveland, OH, 3Johns Hopkins, Baltimore, MD, 4Univ of California, San Francisco, San Francisco, CA

    *Purpose: COVID-19 could bias the Scientific Registry of Transplant Recipients (SRTR) program-specific reports (PSRs), especially if its impact varied geographically.*Methods: Recipients who received transplants from…
  • 2021 American Transplant Congress

    Varicella Hepatitis Mimicking Immune Checkpoint Inhibitor-induced Liver Toxicity

    M. J. Weiss1, X. Zhang2, E. K. Spengler1

    1Gastroenterology and Hepatology, University of Wisconsin, Madison, WI, 2Pathology, University of Wisconsin, Madison, WI

    *Purpose: Nivolumab is an anti-PD-1 monoclonal antibody belonging to a class of immune checkpoint inhibitors (ICI) used for many malignancies. A major limitation to their…
  • 2021 American Transplant Congress

    The Effect of Covid-19 on Offer Acceptance Rates by Age and Race Groups

    A. Wey1, J. Miller1, Y. Ahn1, D. Musgrove1, A. Hart1, N. Salkowski1, M. Skeans1, R. Hirose2, A. Israni1, J. Snyder1, B. Kasiske1

    1SRTR, Minneapolis, MN, 2Univ of San Fransico, San Francisco, CA

    *Purpose: COVID-19 causes more severe complications in older patients and disproportionately leads to poor outcomes in racial minorities. High offer acceptance rates indicate better access…
  • 2021 American Transplant Congress

    Post Pediatric Liver Transplant Immunosuppression: What’s the Caregivers’ Perspective?

    I. D. Batsis1, J. C. Bucuvalas1, E. Eisenberg2, J. Lau2, S. Feng3, E. Perito4

    1Pediatric Hepatology, Mount Sinai Hospital, NY, New York, NY, 2Patient and Family Engaged Partners, SPLIT, New York, NY, 3Pediatric Transplant Surgery, UCSF, San Francisco, CA, 4Pediatric Hepatology, UCSF, San Francisco, CA

    *Purpose: For children with liver transplants (LT), achieving an “ideal outcome” is a balancing act: too little immunosuppression (IS) begets graft injury; too much IS…
  • 2021 American Transplant Congress

    Monoclonal Antibody Therapy for COVID-19 in Solid Organ Transplant Recipients

    Z. A. Yetmar1, E. Beam1, J. C. O'Horo1, R. Ganesh2, D. M. Bierle2, L. Brumble3, M. T. Seville4, R. R. Razonable1

    1Infectious Diseases, Mayo Clinic, Rochester, MN, 2General Internal Medicine, Mayo Clinic, Rochester, MN, 3Infectious Diseases, Mayo Clinic, Jacksonville, FL, 4Infectious Diseases, Mayo Clinic, Scottsdale, AZ

    *Purpose: Bamlanivimab and casirivimab-imdevimab are authorized for emergency use treatment of mild-to-moderate COVID-19 in patients at high-risk for progression to severe disease or hospitalization. For…
  • 2021 American Transplant Congress

    Intestinal Insufficiency May Affect Outcomes After Pediatric Liver Transplantation

    A. K. Batra, M. Desai, J. Yang, K. Cummins, H. Oden-Brunson, H. Ling, S. Beer, J. Goss, N. Galvan

    Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: The purpose of this study is to determine if pre-transplant feeding intolerance is associated with poorer post-OLT (orthotopic liver transplant) outcomes in pediatric liver…
  • 2021 American Transplant Congress

    Evaluation of a Weight-Based Mycophenolate Mofetil Dosing Protocol for Kidney Transplant Maintenance Immunosuppression

    M. Mahoney1, E. Kincaide1, J. Nelson1, K. Klein1, R. Hall1, S. Bhayana2

    1University Health, San Antonio, Department of Pharmacotherapy and Pharmacy Services, The University of Texas at Austin, Pharmacotherapy Division, College of Pharmacy, San Antonio, TX, 2University Transplant Center, University Health, San Antonio, Department of Nephrology, The University of Texas Health Science Center at San Antonio, San Antonio, TX

    *Purpose: To evaluate the safety and efficacy of a weight-based mycophenolate mofetil (MMF) dosing protocol in adult kidney transplant recipients (KTR).*Methods: This single-center retrospective study…
  • 2021 American Transplant Congress

    BK Virus-associated Nephropathy as a Cause of Renal Failure Post-lung Transplantation

    A. Arjuna, M. T. Olson, B. Buddhdev, R. Tenorio, A. Omar, S. Tokman

    Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ

    *Purpose: BK virus-associated nephropathy (BKVAN) is a common cause of renal dysfunction early after renal transplant. BKVAN is much rarer in non-renal solid organ transplant,…
  • 2021 American Transplant Congress

    Covid-19 Incidence Was Initially Associated with Posttransplant Kidney Graft Failure

    A. Wey1, J. Miller1, D. Musgrove1, N. Salkowski1, M. Tabaka1, R. Hirose2, A. Massie3, D. Segev3, A. Israni1, J. Snyder1, B. Kasiske1

    1SRTR, Minneapolis, MN, 2Univ of San Francisco, San Francisco, CA, 3Johns Hopkins, Baltimore, MD

    *Purpose: To better understand the effect of COVID-19 on kidney posttransplant outcomes, we estimated the association of county-level COVID-19 incidence with kidney posttransplant graft failure.*Methods:…
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