Articles tagged "Adverse effects"

2021 American Transplant Congress
Association of Immune Cell Markers with Adverse Outcomes in the First 6 Months Post-pediatric Heart Transplantation
J. Chen¹, D. Salerno², H. Corbo¹, S. Shah³, A. Rothkopf⁴, I. D. Lytrivi⁴
¹Department of Pharmacy, Columbia University Irving Medical Center, New York, NY, ²Department of Pharmacy, Weill Cornell Medical Center, New York, NY, ³College of Pharmacy and Health Sciences, St. John's University, Queens, NY, ⁴Pediatric Cardiology, Columbia University Irving Medical Center, New York, NY
*Purpose: Immunosuppression titration post-orthotopic heart transplant (OHT) is limited to trough level monitoring and does not provide data pertaining to overall state of immunosuppression. Additional…
2021 American Transplant Congress
Association Between Cumulative Antithymocyte Globulin Dosing and Adverse Outcomes in Pediatric Heart Transplant Recipients
J. Chen¹, D. Salerno¹, H. Corbo¹, S. Shah², A. Rothkopf³, I. D. Lytrivi³
¹Department of Pharmacy, NewYork-Presbyterian Hospital, New York, NY, ²College of Pharmacy and Health Sciences, St. John's University, Queens, NY, ³Pediatric Cardiology, Columbia University Irving Medical Center, New York, NY
*Purpose: Lymphocyte depletion via rabbit antithymocyte globulin (rATG) is the most frequently used induction immunosuppressive in pediatric orthotopic heart transplant (OHT). Although outcomes are often…
2021 American Transplant Congress
Beta-lactam Allergies Among Solid Organ Transplant Recipients: Prevalence and Association with Transplant Admission Length of Stay
N. N. Pettit¹, V. Nguyen², C. T. Nguyen¹, A. Lew¹, J. Pisano¹, L. M. Potter¹
¹University of Chicago Medicine, Chicago, IL, ²University of Michigan College of Pharmacy, Ann Arbor, MI
*Purpose: Previous studies have identified that 14-27% of solid organ transplant (SOT) recipients report a beta lactam allergy (BLA). Patients with BLAs often receive less…
2021 American Transplant Congress
Impact of Pre- and Post-transplant Outcomes on Patient-reported Outcomes in a Prospective Multicenter Trial in Kidney Transplantation
J. M. Rohan¹, J. P. Leone², E. Woodle³, D. Kaufman⁴, A. R. Shields³, A. Wiseman⁵, A. J. Matas⁶, P. West-Thielke⁷, E. King³, R. R. Alloway³
¹Children's Hospital Richmond VCU, Richmond, VA, ²Tampa General, Tampa, FL, ³U Cincinnati, Cincinnati, OH, ⁴U Wisconsin, Madison, WI, ⁵Centura Transplant, Denver, CO, ⁶U Minnesota, Minneapolis, MN, ⁷UIC, Chicago, IL
*Purpose: BEST Trial (Belatacept-based Early Steroid-withdrawal Trial) compared belatacept (BELA)-based early steroid withdrawal (ESW) regimens with a tacrolimus (TAC)-based ESW regimen across 2years. CNI free/ESW…
2021 American Transplant Congress
Predictors of Postoperative Atrial Fibrillation in an Urban, Obese Adult Renal Transplant Population
A. Lichvar, Z. Ress, M. Tabriz, H. Jenkins, T. Walsh, I. Tzvetanov, E. Benedetti, M. Campara
University of Illinois at Chicago, Chicago, IL
*Purpose: Postoperative atrial fibrillation (POAF) is a common surgical complication. Renal transplant (RT) recipients possess risk factors that may lead to a higher incidence of…
2021 American Transplant Congress
Tolerability of De Novo and Conversion Belatacept Regimens in Kidney Transplantation
T. Le¹, J. Shoji², J. Phillips¹, D. Quan¹
¹Pharmaceutical Services, UCSF Medical Center, San Francisco, CA, ²Transplant Nephrology, UCSF Medical Center, San Francisco, CA
*Purpose: Belatacept, a selective T lymphocyte co-stimulation blocker, has been shown to be a safe and effective maintenance therapy for immunosuppression. We investigated the long-term…
2021 American Transplant Congress
Outcomes of Granulocyte-Colony Stimulating Factor Use in Pediatric Renal Transplant Recipients: A Pediatric Nephrology Research Consortium Study
R. M. Engen¹, P. L. Weng², W. Shih³, H. Patel⁴, K. Richardson⁵, S. Dowdrick⁶, I. Ashoor⁷, J. Misurac⁸, A. Z. Traum⁹, M. Semanik¹⁰, N. G. Jain¹¹, R. Sreedharan¹²
¹Northwestern University, Chicago, IL, ²University of California Los Angeles, Los Angeles, CA, ³University of Michigan, Ann Arbor, MI, ⁴Nationwide Children's Hospital, Columbus, OH, ⁵Oregon Health & Science University, Portland, OR, ⁶Penn State Health, Hershey, PA, ⁷Louisiana State University, New Orleans, LA, ⁸University of Iowa, Iowa City, IA, ⁹Harvard University, Boston, MA, ¹⁰University of Wisconsin-Madison, Madison, WI, ¹¹Columbia University, New York, NY, ¹²Medical College of Wisconsin, Milwaukee, WI
*Purpose: Neutropenia is common after pediatric kidney transplant and is associated with an increased risk of bacterial infection, allograft loss, and death. Granulocyte colony-stimulating factor…
2021 American Transplant Congress
Non-Alcoholic Fatty Liver Disease in Non-Liver Transplant Patients
R. Claudio¹, C. Conceicao², K. Robichaux², A. Kumar¹, J. Buggs³, N. Kemmer⁴
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²Honors College, University of South Florida, Tampa, FL, ³Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁴Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: The global prevalence of non-alcoholic fatty liver disease (NAFLD) is rising at an alarming rate, driven in large part by an increased incidence of…
2021 American Transplant Congress
Evaluation of the Conversion from Tacrolimus to Sirolimus in Liver Transplant Recipients
H. Bakhtiari¹, S. Todd², H. Snyder², D. Lo², M. Flynn²
¹Mercer University College of Pharmacy, Atlanta, GA, ²Emory University Hospital, Atlanta, GA
*Purpose: The purpose of this study was to compare outcomes in liver transplant patients maintained on standard calcineurin inhibitor (CNI) therapy with tacrolimus versus those…
2021 American Transplant Congress
The Initial Impact of Covid-19 on Reported Graft Failure Rates and Potential Confounding of Srtr Psrs
A. Wey¹, J. Miller¹, D. Musgrove¹, Y. Ahn¹, M. Valapour², N. Salkowski¹, M. Skeans¹, A. Massie³, R. Hirose⁴, D. Segev³, A. Israni¹, J. Snyder¹, B. Kasiske¹
¹SRTR, Minneapolis, MN, ²Cleveland Clinic, Cleveland, OH, ³Johns Hopkins, Baltimore, MD, ⁴Univ of California, San Francisco, San Francisco, CA
*Purpose: COVID-19 could bias the Scientific Registry of Transplant Recipients (SRTR) program-specific reports (PSRs), especially if its impact varied geographically.*Methods: Recipients who received transplants from…