ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Adverse effects"

  • 2018 American Transplant Congress

    Proton Pump Inhibitor Use among Kidney Transplant Recipients

    N. Wilson, S. Bala, B. Concepcion.

    Vanderbilt University Medical Center, Nashville, TN.

    Background: Proton Pump Inhibitors (PPIs) have been associated with CKD and other serious adverse effects. PPI use in the transplant population has not been well-described.…
  • 2018 American Transplant Congress

    Haematological Autoimmune Disorders Associated with Alemtuzumab Induction in Renal and Simultaneous Pancreas and Kidney Recipients

    A. Kousios,1 R. Charif,1 M. Atta,2 A. Luqmani,2 N. Cooper,2 D. Taube.1

    1Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom; 2Department of Haematology, Imperial College NHS Trust, London, United Kingdom.

    Introduction Haematological Autoimmune Disorders (HAD) have been associated with Alemtuzumab (Az); namely immune thrombocytopenia (ITP), autoimmune haemolytic anaemia (AIHA), Evans syndrome (ES) and Red Cell…
  • 2018 American Transplant Congress

    Safety and Efficacy of Sofosbuvir-Based Direct-Acting Antiviral Agents in Kidney Transplant Recipients with HCV: A Systematic Review and Meta-Analysis

    X. Wang,1 P. Tan,1 T. Xiang,2 Y. Qiu,1 T. Song,1 T. Lin.1

    1Department of Urology/Institute of Urology/Organ Transplantation Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; 2West China School of Clinical Medicine, Sichuan University, Chengdu, Sichuan Province, China.

    Background: Outcome data on sofosbuvir (SOF)-based therapy in patients with kidney transplantation (KTx) with hepatitis C virus infection are limited with individual studies having a…
  • 2017 American Transplant Congress

    De Novo Low-Dose Sirolimus versus Mycophenolate Mofetil in Combination with Extended-Release Tacrolimus in Kidney Transplant Recipients.

    J. Lee,1 K. Huh,1 J. Ha,2 C.-K. Oh,3 M. Ju,4 C.-D. Kim,5 H. Cho,6 C. Jung,7 B. Lim,8 Y. Kim.1

    1Transplantation Surgery, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; 2Surgery, Seoul National University Hospital, Seoul, Republic of Korea; 3Surgery, Ajou University Hospital, Suwon, Republic of Korea; 4Surgery, Gangnam Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea; 5Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea; 6Surgery, Ulsan University Hospital, Ulsan, Republic of Korea; 7Surgery, Korea University Anam Hospital, Seoul, Republic of Korea; 8Pathology, Yonsei University College of Medicine, Seoul, Republic of Korea

    Previous studies reported that tacrolimus (TAC) with high-dose sirolimus (SRL) was associated with worse outcomes in kidney transplantation, compared to TAC with mycophenolate mofetil (MMF.).…
  • 2017 American Transplant Congress

    Tacrolimus Trough Concentration Variability and Disparities in African American Kidney Transplantation.

    D. Taber, Z. Su, A. Posadas, M. Gebregziabher, L. Egede, D. Dubay, J. McGillicuddy, C. Bratton, S. Nadig, K. Chavin, P. Baliga.

    MUSC, Charleston, SC

    Low tacrolimus (FK) trough concentrations have been associated with higher risk of acute rejection, particularly within African-American (AA) kidney transplant recipients; less is known about…
  • 2017 American Transplant Congress

    Applicability and Safety of a Regulatory T Cell Therapy in Adult Liver Transplantation: The “ThRIL” Phase I First-in-Human Trial.

    G. Whitehouse, N. Safinia, S. Thirkell, L. Fry, N. Grageda, M. Martinez-Llordella, R. Lechler, N. Heaton, G. Lombardi, A. Sanchez-Fueyo.

    MRC Centre for Transplantation, King's College London, London, United Kingdom

    Aim“ThRIL” is a multiple site, open-label, uncontrolled, phase I clinical trial assessing the safety and applicability of a CD4+CD25+FOXP3+ regulatory T cell (Treg) immunotherapy in…
  • 2017 American Transplant Congress

    Dementia and Alzheimer's Disease Among Older Kidney Transplant Recipients.

    M. McAdams DeMarco, S. Bae, N. Chu, A. Gross, C. Brown IV, E. Oh, P. Rosenberg, K. Neufeld, R. Varadhan, M. Albert, J. Walston, D. Segev.

    Johns Hopkins, Baltimore, MD

    Background: Kidney transplantation (KT) is a growing treatment option for older ESRD patients. Older recipients may develop post-KT dementia and Alzheimer's disease (AD) associated with…
  • 2017 American Transplant Congress

    Impact of Donor Asystole in Intestine Transplant.

    J. Schroering, C. Kubal, R. Mangus.

    Surgery, Indiana University, Indianapolis, IN

    Intestine transplantation has a high risk of post-transplant complications. For this reason, many intestine transplant centers are conservative in their choice of deceased donors, using…
  • 2017 American Transplant Congress

    Single-Center Initial Experience in Treating Chronic Hepatitis C in Kidney Transplant Recipients.

    G. Meinerz, C. da Silva, R. Bruno, E. Keitel, V. Garcia.

    Nephrology and Kidney Transplant Department, ISCMPA, Porto Alegre, RS, Brazil

    Chronic hepatitis C (HCV) infection is a prevalent condition in end-stage renal disease and presents an important clinical challenge in kidney transplant recipients (KTR). Interferon-based…
  • 2017 American Transplant Congress

    Alemtuzumab Induction Is Safe, and Permits the Avoidance of Steroids in the Majority of Renal Transplant Recipients.

    A. Seitz,1 M. Robb,2 N. Ahmad,1 A. McLean,3 D. Taube,3 R. Johnson,2 R. Baker.1

    1Renal Unit, St James's Hospital, Leeds, United Kingdom; 2Organ Donation and Transplantation Studies, NHS Blood and Transplant, Bristol, United Kingdom; 3West London Renal and Transplant, Hammersmith Hospital, London, United Kingdom

    IntroductionThe introduction of alemtuzumab into routine clinical use has been hindered by safety concerns surrounding its prolonged effect on the lymphoid compartment. Here we report…
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