2018 American Transplant Congress
Comprehensive Assessment of NSAID Use and Potential Nephrotoxicity Risk in Adult Veteran Kidney Transplant Recipients
Ralph H Johnson VAMC, Charleston, SC.
Background: NSAID use is generally recommended to be avoided in kidney transplantation (KTX), but there is paucity in the studies assessing their safety within this…2018 American Transplant Congress
Antiproteinuric Effect of Spironolactone in Renal Transplantation: Effectiveness and Clinical Outcomes
University of Campinas, Campinas, Sao Paulo, Brazil.
Background: aldosterone is involved in development of fibrosis in kidney transplantation. Blockade of aldosterone receptor appears to be effective in treatment for chronic allograft dysfunction,…2018 American Transplant Congress
The BEST Trial: A Prospective Randomized Multicenter Trial of Belatacept-Based CNI- and Corticosteroid-Free Immunosuppression
Previous large multicenter belatacept (BELA)-based CNI- and steroid-free immunosuppressive trials have not enrolled to completion due to safety concerns. The BEST Trial (Belatacept-based Early Steroid…2018 American Transplant Congress
Proton Pump Inhibitor Use among Kidney Transplant Recipients
Vanderbilt University Medical Center, Nashville, TN.
Background: Proton Pump Inhibitors (PPIs) have been associated with CKD and other serious adverse effects. PPI use in the transplant population has not been well-described.…2018 American Transplant Congress
Haematological Autoimmune Disorders Associated with Alemtuzumab Induction in Renal and Simultaneous Pancreas and Kidney Recipients
Introduction Haematological Autoimmune Disorders (HAD) have been associated with Alemtuzumab (Az); namely immune thrombocytopenia (ITP), autoimmune haemolytic anaemia (AIHA), Evans syndrome (ES) and Red Cell…2018 American Transplant Congress
Safety and Efficacy of Sofosbuvir-Based Direct-Acting Antiviral Agents in Kidney Transplant Recipients with HCV: A Systematic Review and Meta-Analysis
Background: Outcome data on sofosbuvir (SOF)-based therapy in patients with kidney transplantation (KTx) with hepatitis C virus infection are limited with individual studies having a…2018 American Transplant Congress
Metabolic Complications 10-Years after Kidney Transplant
Background: Improving long-term outcomes is an important but unmet need after kidney transplant. Protocol renal allograft biopsies taken 10-years after transplant frequently show diabetic nephropathy…2018 American Transplant Congress
Use of Granulocyte Colony-Stimulating Factor for Leukopenia Post-Renal Transplant
Purpose: Leukopenia is a frequent complication in renal transplant recipients (RTRs). Granulocyte colony-stimulating factor (G-CSF) accelerates white blood cell (WBC) count recovery; but, published experience…2018 American Transplant Congress
Association between Everolimus Trough Levels, Onset of Related Adverse Events, and Treatment Discontinuation after Liver Transplantation: 24-Month Results from the H2304 Study
Purpose: Evaluation of mammalian target of rapamycin inhibitor (mTORi)-related adverse events (AEs) and drug trough levels (C0) at onset may aid their management in liver…2018 American Transplant Congress
Preventing Recurrence of Incisional Hernia after Liver Transplantation
Transplant Surgery, Indiana University, Indianapolis, IN.
Background: Incisional hernia is a well-known complication of orthotopic liver transplantation (OLT). Although factors that affect incidence of hernia after OLT have been described, recurrence…
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