2019 American Transplant Congress
Microfluidic Study Analyzing the Effect of Immediate-Release and Extended-Release Tacrolimus on Islet Function
*Purpose: The purpose of this analysis was to quantify the impact of 2 tacrolimus pharmacokinetic profiles on functional changes within human islet cells using a…2019 American Transplant Congress
Evaluating Potentially Inappropriate Prescribing in Older Kidney Transplant Recipients
*Purpose: While the Beers criteria (BC) and STOPP criteria (SC) have been validated in several patient populations to reduce medication use leading to adverse drug…2018 American Transplant Congress
Conversion from Twice Daily Immediate Release Tacrolimus to Once Daily Extended Release Tacrolimus (LCP-Tacro) in High Risk Kidney Transplant Recipients
Extended release once daily tacrolimus (LCP-Tacro) has demonstrated non inferiority to immediate release twice daily tacrolimus (IR-Tac) in kidney transplantation. These data are limited by…2018 American Transplant Congress
Side Effect Profile of Everolimus in Liver Transplant Patients
IntroductionUse of calcineurin inhibitors has been the mainstay of antirejection medications after liver transplant (LT). However, renal toxicity from these drugs remains troublesome. By comparison,…2018 American Transplant Congress
Safety and Tolerability of Therapy for Latent Tuberculosis Infection: A 16-Year Review
Transplant Infectious Diseases, UHN, Toronto, ON, Canada.
Introduction:Screening and therapy of latent tuberculosis infection (LTBI) is recommended in transplant candidates. However, data on therapy of LTBI with fluoroquinolones are limited. We aimed…2018 American Transplant Congress
Isavuconazole – The Real-World Use Experience
Cleveland Clinic Foundation, Cleveland, OH.
Isavuconazole (ISV) is a new triazole approved for treatment of mucormycosis and aspergillosis. Data on its effectiveness outside clinical trials and in patients receiving prior…2018 American Transplant Congress
Comprehensive Assessment of NSAID Use and Potential Nephrotoxicity Risk in Adult Veteran Kidney Transplant Recipients
Ralph H Johnson VAMC, Charleston, SC.
Background: NSAID use is generally recommended to be avoided in kidney transplantation (KTX), but there is paucity in the studies assessing their safety within this…2018 American Transplant Congress
Antiproteinuric Effect of Spironolactone in Renal Transplantation: Effectiveness and Clinical Outcomes
University of Campinas, Campinas, Sao Paulo, Brazil.
Background: aldosterone is involved in development of fibrosis in kidney transplantation. Blockade of aldosterone receptor appears to be effective in treatment for chronic allograft dysfunction,…2018 American Transplant Congress
The BEST Trial: A Prospective Randomized Multicenter Trial of Belatacept-Based CNI- and Corticosteroid-Free Immunosuppression
Previous large multicenter belatacept (BELA)-based CNI- and steroid-free immunosuppressive trials have not enrolled to completion due to safety concerns. The BEST Trial (Belatacept-based Early Steroid…2018 American Transplant Congress
Proton Pump Inhibitor Use among Kidney Transplant Recipients
Vanderbilt University Medical Center, Nashville, TN.
Background: Proton Pump Inhibitors (PPIs) have been associated with CKD and other serious adverse effects. PPI use in the transplant population has not been well-described.…
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