Articles tagged "Adverse effects"

2019 American Transplant Congress
Postoperative Atrial Fibrillation in Kidney Transplant Recipients: A Retrospective Study Evaluating Risk of Anticoagulation
P. Serrano Rodriguez¹, A. Vijayakumar², P. D. Strassle³, K. Szempruch¹, C. S. Desai¹, A. Vijay¹, A. H. Toledo¹, D. A. Gerber¹
¹Abdominal Transplant SUrgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³General Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC
*Purpose: Patients with atrial fibrillation (AF) have a higher risk of mortality and adverse cardiovascular events. Pre-operative AF has around 5-9% prevalence and roughly 5%…
2019 American Transplant Congress
Obesity Induced IL-18 Production Impairs FOXP3+ Treg Function and Increases Risk of Primary Graft Dysfunction in Lung Transplant Recipients
W. W. Hancock¹, T. Zhang¹, U. H. Beier¹, A. Samanta¹, R. Han¹, L. Wang¹, J. Jiao¹, J. M. Diamond², D. S. Wilkes³, D. J. Lederer⁴, R. A. Simmons², J. D. Christie², T. Akimova²
¹Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³University of Virginia, Charlottesville, VA, ⁴Columbia University, New York, NY
*Purpose: Lung transplantation is a life-saving treatment for terminal lung diseases but long-term outcomes are poor, beginning with possible development of primary graft disease (PGD)…
2019 American Transplant Congress
Technology Triggered Adherence Intervention – Preliminary Findings
T. E. Kaiser¹, N. S. Ejaz¹, S. Tremblay¹, N. J. Parrish², J. Benavides², B. Rehe², A. Govil¹, E. S. Woodle¹, R. R. Alloway¹
¹University of Cincinnati, Cincinnati, OH, ²UC Health, Cincinnati, OH
*Purpose: Medication non-adherence (M-NA) after renal transplant (RT) increases the risk of graft failure. We conducted a prospective, randomized, single center trial to evaluate 3…
2019 American Transplant Congress
Efficacy and Safety of Alemtuzumab versus Basiliximab Induction in Lung Transplantation
J. Choe, J. Au, A. Diamond, C. Ruggia-Check, S. Sehgal, F. Cordova, N. Shigemura, S. Keshavamurthy, Y. Toyoda
Temple University Hospital, Philadelphia, PA
*Purpose: Minimal literature exists regarding alemtuzumab for induction in lung transplantation but is the preferred agent at Temple University Hospital (TUH). Basiliximab is reserved for…
2019 American Transplant Congress
Patient-Reported Outcomes in a Prospective Multicenter Trial of Belatacept-Based CNI- and Corticosteroid-Free Immunosuppression Regimens in Kidney Transplantation
J. M. Rohan¹, J. P. Leone², E. S. Woodle³, D. Kaufman⁴, A. R. Shields³, A. Wiseman⁵, A. J. Matas⁶, P. West-Thielke⁷, E. King³, R. R. Alloway³
¹Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, VA, ²Tampa General Hospital, Tampa, FL, ³University of Cincinnati College of Medicine, Cincinnati, OH, ⁴University of Wisconsin – Madison, Madison, WI, ⁵University of Colorado - Denver, Denver, CO, ⁶University of Minnesota Medical Center, Minneapolis, MN, ⁷University of Illinois – Chicago, Chicago, IL
*Purpose: Previous trials have not examined differences in patient-reported outcomes (PRO) between belatacept (BELA)- and tacrolimus (TAC)-based therapies in adult kidney transplant (KTx) patients (pts).…
2019 American Transplant Congress
Multi-Disciplinary Considerations Concerning the Impacts of Kidney Transplantation on Cervical and Lumbar Spinal Fusion Operations
L. Mugge, C. Gallagher, W. Qu, A. Caras, N. Henkel, O. Ekwenna, J. Ortiz
The University of Toledo Medical Center, Toledo, OH
*Purpose: Improvements in postoperative care for renal transplant patients has increased both the duration and quality of life for patients. These patients are now able…
2019 American Transplant Congress
Infectious Complications in Tocilizumab-Treated Kidney Transplant Recipients
S. Sethi, A. Peng, R. Najjar, A. Vo, S. Jordan, E. Huang
Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Tocilizumab blocks IL-6 signaling, inhibiting maturation of B cells to plasma cells and antibody production. We have used tocilizumab since 2012 to treat kidney…
2019 American Transplant Congress
Severe Hyponatremia with Intraoperative Desmopressin Use in (Deceased and Living Donor) Renal Transplant Recipients
M. Gill, S. Kuppachi, C. Thomas
Division of Nephrology, University of Iowa Hospital and Clinics, Iowa City, IA
*Purpose: Desmopressin (DDAVP) is used for hemostasis in patients with factor VIII deficiency, von Willebrand disease and platelet function defects including that seen in patients…
2019 American Transplant Congress
Elevated Visceral Adiposity is Associated with Post-Liver Transplant Mortality and Poorly Correlates with BMI in a Prospective Cohort Study
R. Sharma, R. Rosenblatt, R. Knotts, J. Pisa, E. Verna
Division of Liver Diseases and Transplantation, Columbia Univerisity Medical Center, New York, NY
*Purpose: Obesity is increasingly common in end-stage-liver disease (ESLD). While obesity adversely affects outcomes, whether abnormalities in specific adipose tissue (AT) compartments lead to increased…
2019 American Transplant Congress
Significant Implications of Prior Transplantation on Treatment and Outcomes of Patients Suffering from Traumatic Brain Injury
L. Mugge, W. Qu, C. Gallagher, A. Caras, N. Henkel, O. Ekwenna, J. Ortiz
The University of Toledo Medical Center, Toledo, OH
*Purpose: Recent events in the media and sporting industry highlight traumatic brain injury (TBI) as a major health concern, having implications in many areas of…