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2015 American Transplant Congress » Poster Session D: Kidney Immunosuppression: Drug Minimization

Date: Tuesday, May 5, 2015

Time: 5:30pm-6:30pm

Location: Exhibit Hall E

Session Type: Poster Session

Meeting: 2015 American Transplant Congress

5:30pm-6:30pm
"What's the Mileage?" Determining the Length of Time in Which Renal Function Returns to Pre-Calcineurin Discontinuation Levels in Patients With Interstitial Fibrosis

A. Diez, J. Von Visger, U. Nori, T. Pesavento, M. Henry, E. Davies, R. Pelletier.

5:30pm-6:30pm
12-Month Athena Study: Everolimus Vs. Standard Regimen in De Novo Renal Transplant Recipients

C. Sommerer,1 B. Suwelack,1 D. Dragun,1 I. Hauser,1 P. Schenker,1 D. Bäumer,2 B. Nashan,1 F. Thaiss.1

5:30pm-6:30pm
2-Year Results on Renal Function and Safety for Everolimus plus Reduced-Exposure Calcineurin Inhibitor in Living Donor Kidney Transplant Recipients

T. Yagisawa,1 N. Ishikawa,1 N. Goto,2 I. Nakajima,3 O. Kamisawa,4 S. Fuchinoue.3

5:30pm-6:30pm
24 Month Post Transplantation Follow Up of the Certitem Trial

E. Rondeau,1 E. Cassuto,2 V. Vuiblet,3 C. Legendre,4 P. Merville,5 Y. Le Meur,6 B. Moulin,7 P. Westeel,8 B. Hurault De Ligny,9 A. Lécuyer,10 M. Tindel,11 N. Kamar.12

5:30pm-6:30pm
A 52-Week, Multicenter, Prospective, Observational, Non-Interventional, Open-Label Study to Assess the Effectiveness, Safety and Tolerability of Everolimus in Kidney Transplant Patients in Taiwan

S.-M. Wang,1 P.-C. Lee,2 J.-D. Lian,3 K.-H. Shu,4 S.-T. Wu,5 H.-C. Chen,6 C.-C. Huang,7 M.-S. Wu,8 Y.-C. Tian,9 Y.-J. Chiang,10 Y.-T. Chen,11 H.-P. Wang.12

5:30pm-6:30pm
Acute Kidney Injury in the MELD Era of Liver Transplantation. Are Calcineurin Inhibitors So Problematic for Renal Function?

R. Ciria Bru, I. Gómez Luque, M. Cortés Cerisuelo, P. López Cillero, J. O'Grady, M. de la Mata, N. Heaton, J. Briceño Delgado.

5:30pm-6:30pm
Calcineurin Inhibitor-Free Immunossupresion After Kidney Transplantation, Using Everolimus De Novo – Single Center Experience

M. Stronka, Z. Adamska, L. Cichanska, J. Kubiak, M. Gamrat, M. Karczewski.

5:30pm-6:30pm
Calcineurin Inhibitors (CNI) Minimization Associated With Mammalian Target of Rapamycin Inhibitors (i-mTOR) to Improve Renal Function in Renal Grafts from Uncontrolled Donation After Cardiac Death Donors (UDCDD)

M. Molina,1 E. Gutierrez,1 S. González-Sanchidrian,2 E. González,1 J. Cabrera,1 N. Polanco,1 A. Hernández,1 A. Sevillano,1 M. Praga,1 A. Andres.1

5:30pm-6:30pm
Calcineurin-Inhibitor Conversion to mTOR Inhibitor in Renal Transplant Recipients Leads to Worse Long Term Clinical Outcomes

A. Alvarado,1 A. Shetty,1 O. Traitanon,1 J. Leventhal,1 V. Mas,2 D. Chhabra,3 J. Matthews,1 L. Gallon.1

5:30pm-6:30pm
Comparison of Efficacy and Renal Function in KidneyTransplant Recipients Receiving Tacrolimus (TAC)-Based Immunosuppressive Regimens in Combination With Everolimus (EVR) or Mycophenolate (MPA)

A. Ferreira,1 C. Felipe,1 P. Ueno,1 P. Hannun,1 P. Ruppel,1 T. Sandes-Freitas,1 H. Proença,3 J. Medina- Pestana,1 H. Tedesco-Silva.1

5:30pm-6:30pm
Conversion from Immediate to Prolonged Release Tacrolimus Did Not Change Intra-Patient Variability in Renal Transplant Patients

T. El-Nahhas,1,2 M. Moreton,2 J. Popoola,3 S. Abat,3 A. Johnston,1,2 I. MacPhee.3

5:30pm-6:30pm
Delayed Tacrolimus (TAC) to Rapamycin (RAPA) Conversion in Renal Transplant Recipients With DGF/SGF

A. Haririan,1 D. Klassen,1 M. Keshtkar,1 C. Drachenberg,2 T. Dowling,3 E. Ramos,1 R. Ugarte,1 C. Cangro,1 M. Weir.1

5:30pm-6:30pm
Early Steroid Withdrawal and Calcineurin Inhibitor Minimization Protocols for Maintenance Immunosuppression: A Single Center 10-Year Experience

R. Lopez-Soler,1 L. Park,3 J. Martinolich,2 D. Conti.1

5:30pm-6:30pm
Early Steroid Withdrawal and Infection Risk in Kidney Transplant Recipients

S. Bae, L. Kucirka, C. Durand, B. Orandi, R. Avery, D. Segev.

5:30pm-6:30pm
Everolimus Plus Reduced-Exposure Calcineurin Inhibitor Versus Mycophenolate Mofetil Plus Standard-Exposure Calcineurin Inhibitor: 2-Year Results in Living Donor Kidney Transplant Recipients

Y. Watarai,1 N. Akutsu,2 K. Saito,3 Y. Nakagawa,3 O. Kamisawa,4 T. Kenmochi.5

5:30pm-6:30pm
Explorative Analysis of ZEUS After 5 Years: Histological Assessment from Biopsy Analyses

U. Eisenberger,1 K. Budde,1 O. Witzke,1 F. Lehner,1 C. Sommerer,1 R. Wuethrich,3 P. Reinke,1 A. Muehlfeld,1 K. Heller,1 R. Stahl,1 H. Wolters,1 I. Hauser,1 M. Porstner,2 W. Arns.1

5:30pm-6:30pm
Factors Affecting Efficacy Outcomes at 12 and 24-Months After Kidney Transplantation in Patients from the A2309 Study

C. Escrig,1 G. Colussi,2 R. Roland,2 M. Vergara,3 Z. Wang.3

5:30pm-6:30pm
Increasing Tacrolimus Exposure to Minumize Chronic Rejection: How Can We Do It? What Are the Risks?

T. Hsu,1 J. Yin,1 L. Awdishu,1 J. Kerr,1 R. Steiner.2

5:30pm-6:30pm
Influence of CYP3A5 and ABCB1 Genotypes on Pharmacokinetics of Immediate and Prolonged Release Tacrolimus Preparations

T. Elnahhas,1,2 T. Lee,2 M. Moreton,2 D. McKeown,2 J. Popoola,3 R. Ramkhelawon,3 A. Johnston,1,2 I. MacPhee.3

5:30pm-6:30pm
Month 48 Follow-Up Results of HERAKLES Trial on Three Different Treatment Regimen and Switching Off Behaviour in De Novo Renal Transplant Patients

W. Arns,1 K. Budde,1 C. Sommerer,1 O. Witzke,1 M. Guba,1 J. Jacobi,1 B. Vogt,3 P. Reinke,1 I. Hauser,1 R. Stahl,1 T. Rath,1 D. Baeumer,2 M. Porstner,2 M. Zeier,1 F. Lehner,1 V. Kliem.1

5:30pm-6:30pm
NFAT Regulated Cytokine Gene Expression for Immune Monitoring in Kidney Transplant Recipients

V. Tatapudi, A. Webber, C. Leung, F. Vincenti.

5:30pm-6:30pm
Once Daily Dosing Is as Effective as Twice Daily Dosing of Immediate Release Tacrolimus

L. Bowman,1 T. Horwedel,1 J. Hagopian,1 B. Bone,2 H. Wijeweera,2 D. Brennan.2

5:30pm-6:30pm
Once-a-Day Administration of CNIs, mTOR and MMF Is Safe in De Novo Renal Transplant Recipients: 1-Year Results of a Pilot Study

G. Spagnoletti, M. Salerno, E. Favi, J. Pedroso, J. Romagnoli, F. Citterio.

5:30pm-6:30pm
Outcomes of Hispanic Kidney Transplant Recipients Under a Cyclosporine Versus Tacrolimus Based Immunosuppression Regimen

P. West-Thielke,1 M. Campara,2 A. Ladik,1 E. Terranova,2 E. Benedetti,1 J. Thielke.2

5:30pm-6:30pm
Outcomes of Kidney Transplant Recipients Minimally Immunosuppressed: A Cohort Study Analysis

A.-H. Querard,1,2,3 F. Gillaizeau,2,1 G. Couvrat-Desvergne,1,2,3 J. Dantal,1,4,5 P. Daguin,1 S. Le Floch,1 S. Castagnet,6 S. Brouard,1,4 Y. Foucher,2,1 M. Giral.1,2,4,5

5:30pm-6:30pm
Pharmacokinetics of Everolimus (EVL) in Elderly Recipients Under Low-Tacrolimus(TAC)/Everolimus in the First Year After Renal Transplantation. Data from the NEverOLd Trial

E. David-Neto,1 P. Romano,2 F. Agena,1 P. Ebner,2 A. Triboni,1 F. Ramos,1 N. Galante,1 F. Lemos.1

5:30pm-6:30pm
Pharmacokinetics of Mycophenolic Acid (MPA) in Elderly Compared to Young Recipients in the First Year After Renal Transplantation. Data from the NEverOLd Trial

P. Romano,1 F. Agena,2 P. Ebner,1 A. Triboni,2 F. Ramos,2 N. Galante,2 F. Lemos,2 N. Sumita,1 E. David-Neto.2

5:30pm-6:30pm
Pharmacokinetics of Tacrolimus (TAC) in Elderly Compared to Young Recipients in the First Year After Renal Transplantation. Data from the NEverOLd Trial

E. David-Neto,1 P. Romano,2 A. Triboni,1 F. Agena,1 P. Ebner,2 F. Ramos,1 N. Galante,1 F. Lemos.1

5:30pm-6:30pm
Plasma 4β-Hydroxycholesterol Measurement as a Potential Biomarker for CYP3A5 Activity in Informing Tacrolimus Dosing

T. Elnahhas,1,2 E. de Jonge,4 T. Lee,2 B. van Zelst,4 J. Popoola,3 R. Ramkhelawon,3 R. van Schaik,4 A. Johnston,1,2 I. MacPhee.3

5:30pm-6:30pm
Post Hoc Subgroup Analysis of ZEUS: Outcome on Renal Function, Efficacy and Safety in Living-Donor Kidney Transplant Recipients After Conversion from a Calcineurin Inhibitor to an Everolimus Based Regimen: 5 Year Follow-Up Data

F. Lehner,1 K. Budde,1 R. Wuethrich,2 P. Reinke,1 W. Arns,1 A. Muehlfeld,1 U. Eisenberger,1 R. Stahl,1 K. Heller,1 O. Witzke,1 B. Suwelack,1 H. Wolters,1 I. Hauser,1 M. Porstner,3 C. Sommerer.1

5:30pm-6:30pm
Prospective Study of a Steroid Free, Low Dose Tacrolimus and Everolimus Combination Regimen in Kidney Transplant

A. Shetty,1 J. Leventhal,1 O. Traitanon,1 A. Alvarado,1 V. Mas,2 J. Mathew,1 E. Tantisattamo,1 L. Gallon.1

5:30pm-6:30pm
Reduced Intensity Immunosuppression Protocol Lowers Drug Costs and May Decrease Incidences of BK Viremia and Readmissions After Kidney and Kidney/Pancreas Transplant

M. Mariski,1 A. DeGolovine,2 W. Dar,2 J. Bynon,2 H. Adrogué,2 M. Hobeika.2

5:30pm-6:30pm
Reduction of Tacrolimus With Everolimus Addition in Maintenance Immunosuppression Improves Calcineurin Inhibitor-Induced Arteriolopathy in Kidney Allografts

M. Miura,1 H. Higashiyama,1 Y. Fukasawa.2

5:30pm-6:30pm
Safety and Efficacy of Low Dose and Very Low Dose Extended-Release Tacrolimus / MMF in De Novo Kidney Transplant Recipients

Y. Watarai,1 M. Okada,1 K. Futamura,1 K. Ito,1 T. Yamamoto,1 M. Tsujita,1 T. Hiramitsu,1 N. Goto,1 S. Narumi,1 T. Kobayashi.2

5:30pm-6:30pm
Steroid-Free Quadruple Induction Regimen With Basiliximab, Everolimus, Mycophenolate and Very Low Dose Tacrolimus Reduces Incidence of Biopsy-Proven Acute Rejection and Toxicity Profile Compared to the Standard Triple Regimen

M. Miura, H. Higashiyama.

5:30pm-6:30pm
Superior Renal Function in an Everolimus-Based Calcineurin Inhibitor Free Regimen Compared to Standard Cyclosporine/Mycophenolate and Low Cyclosporine/Everolimus: Follow-Up of the HERAKLES Study at Month 48

K. Budde,1 C. Sommerer,1 P. Weithofer,1 O. Witzke,1 M. Guba,1 J. Jacobi,1 B. Vogt,3 I. Hauser,1 R. Stahl,1 P. Reinke,1 T. Rath,1 D. Baeumer,2 M. Porstner,2 M. Zeier,1 F. Lehner,1 W. Arns.1

5:30pm-6:30pm
Treatment With Everolimus and Reduced-Exposure Cyclosporine Is Efficacious in De Novo Renal Transplant Recipients at Increased Risk for Efficacy Failure: Post-Hoc Analysis from the A2309 Study

M. Carmellini,1 V. Garcia,1 Z. Wong,2 M. Vergara,2 C. Escrig,2 G. Russ.1

5:30pm-6:30pm
mTOR-Based CNI Minimization Vs Withdrawal in African American Kidney Transplant Recipients

J. Fleming,1 D. Taber,2 N. Pilch,1 H. Meadows,1 C. Mardis,1 J. McGillicuddy,2 S. Nadig,2 K. Chavin,2 P. Baliga,2 C. Bratton.2

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