2016 American Transplant Congress » Poster Session C: Antibody Mediated Rejection: Session #1

6:00pm-7:00pm

A Novel Study to Determine the Association of Pre-Transplant Donor Specific Antibody and AT₁R Antibody with Kidney Transplant Outcomes Prior to Adoption of Solid Phase Antibody Assays.

R. Redfield, B. Astor, B. Jung-Hynes, D. Mandelbrot, D. Kaufman, A. Djamali, T. Ellis.

6:00pm-7:00pm

Anti-HLA Antibodies in Allogeneic and Autologous Hematopoietic Stem Cell Transplantation.

A. Bertocchi, L. Requiao-Moura, M. Torres, E. Tonato, M. Durao Junior, A. de Matos, N. Hamershclak, A. Pacheco-Silva.

6:00pm-7:00pm

Antibody Titers as Predictors of Kidney Graft Outcomes.

A. Gilbert,¹ M. Zaheer,¹ O. Timofeeva,² S. Rosen-Bronson,² M. Awwad,² D. Li,² M. Grafals,¹ B. Javaid,¹ P. Abrams,¹ J. Verbesey,¹ M. Cooper.¹

6:00pm-7:00pm

Antibody-Mediated Rejection Can Be Assessed by Histology When DSA Is Unknown or Negative.

J. Reeve,¹ P. Halloran.²

6:00pm-7:00pm

Association of Genetic Polymorphisms in Complement Independent Pathways with Donor Specific Antibodies in Kidney Allograft Recipients.

Y. Chang,^1,2 T. Shah,^1,3 D. Min.¹

6:00pm-7:00pm

Baseline Donor Specific Antibody (DSA) More Predictive of Chronic Antibody Mediated Rejection (CAMR) Than the Change in DSA Over Time.

D. Mitema,¹ W. Cheungpasitporn,¹ M. Stegall,¹ F. Cosio,¹ M. Gandhi,² C. Schinstock.¹

6:00pm-7:00pm

Breadth of HLA-Specific B Cell Reactivity and Frequency Assessed by a Novel Multiplex Bead Based Assay Predicts and Correlates with Rejection in Kidney Transplant Recipients.

A. Akl, Z. Ilyas, O. Traitanon, L. Gallon, A. Tambur, M. Ansari.

6:00pm-7:00pm

Clinical Significance of C3d Binding Donor Specific Anti-HLA Antibodies (DSA) Detected by Single Antigen Beads (SAB) After Kidney Transplantation.

R. Pelletier,¹ I. Balazs,² P. Adams,³ P. Steller,³ N. DiPaola,⁴ L. Rankin,³ A. Diez,⁵ M. Henry.¹

6:00pm-7:00pm

Comparison of EDTA, DTT and Dilutions to Abrogate the Prozone Effect in Luminex-Based HLA Antibody Assays.

M. Pando, S. Franklin, L. Nelson, Y. Desmarteau, A. Jaramillo.

6:00pm-7:00pm

Deceased Donor Kidney Transplantation in the Setting of Positive Donor-Specific Antibodies.

B. Orandi,¹ J. Montgomery,² E. Kraus,¹ D. Segev,¹ R. Montgomery,¹ N. Alachkar.¹

6:00pm-7:00pm

Early Onset Acute Antibody Mediated Rejection (ABMR) Is More Common in Female Than in Male Recipients of a Living Unrelated Donor (LURD) Renal Transplant and Is Associated with the Presence of Preformed Donor Specific Antibodies (DSA).

D. Soonawala,¹ K. Groeneweg,¹ F. van der Toorn,¹ S. Heidt,² D. Roelen,² F. Claas,² J. de Fijter.¹

6:00pm-7:00pm

Glomerular Capillary C4d Staining without Evidence of Rejection Is Associated with Worse Graft Function in ABO-Incompatible Kidney Transplantation.

D. Toki,¹ M. Inui,¹ M. Okumi,² H. Ishida,² K. Setoguchi,¹ T. Shimizu,² K. Unagami,² K. Tanabe.²

6:00pm-7:00pm

IVIG and High Dose Steroid Treatment of Transplant Glomerulopathy Effectively Slows Progression of Loss of Renal Allograft Function.

K. Sablik,¹ C. Looman,² M. Clahsen-van Groningen,³ J. Damman,³ D. Roelen,⁴ M. van Agteren,¹ M. Betjes.¹

6:00pm-7:00pm

Impact of Early Red Blood Cell Transfusion After Kidney Transplantation on De Novo HLA Sensitization in the Setting of Antithymocyte Globulin Induction.

T. Jouve,^1,2 G. Rigault,^1,2 B. Janbon,¹ R. Tetaz,¹ N. Terrier,¹ D. Masson,³ L. Rostaing,^1,2 P. Malvezzi.¹

6:00pm-7:00pm

Inconsistent HLA Antibody Reactivity Detected with Different Solid-Phase Assays.

A. Jaramillo,¹ L. Nelson,¹ Y. Desmarteau,¹ B. Labuda,² K. Barrios,² J. Lunz,² R. Heilman,³ M. Pando.¹

6:00pm-7:00pm

Inflammation Amplifier, a Chemokine Inducer in Non-Immune Cells in Kidney Transplantation Graft.

H. Higuchi,^1,2 H. Bando,² J. Jing-Jing,² T. Atsumi,² D. Iwami,¹ K. Morita,¹ N. Shinohara,¹ M. Murakami.²

6:00pm-7:00pm

Kidney Graft Homing of De Novo Donor Specific HLA Antibodies Is an Early Step within the Antibody-Mediated Graft Damage Process.

A. Nocera,¹ M. Cioni,² A. Tagliamacco,¹ A. Innocente,³ I. Fontana,⁴ A. Magnasco,² A. Nocco,³ A. Sementa,² G. Garibotto,¹ G. Ghiggeri,² M. Cardillo,³ P. Comoli,⁵ F. Ginevri.²

6:00pm-7:00pm

Membranoproliferative Glomerulonephritis Pattern without Immunoglobulin and Complement Deposition in Renal Allograft Was Related to the Injury of Antibody-Mediated Rejection.

J. Wen, F. Xu, J. Chen, X. Li, M. Zhang, Z. Zhang, Z. Liu.

6:00pm-7:00pm

Optimized Flow Cytometry Crossmatch with Increased Sensitivity and Specificity.

K. Barrios,¹ J. Lunz,¹ B. Labuda,¹ D. Magas,¹ D. Freedom,¹ K. Szewczyk,¹ M. Jendrisak,¹ A. Jaramillo.^1,2

6:00pm-7:00pm

Patients Treated with Belatacept Show Low Levels of APRIL and HLA Antibodies.

M. Rial,¹ N. Ambrosi,² F. Caro,² D. Curcio,¹ J. Salaberry,² O. Guardia,¹ A. Dotta,¹ D. Guerrieri,² K. Padros,³ E. Chuluyan,² D. Casadei.

6:00pm-7:00pm

Postoperative Rebound of Anti-Blood Type Antibodies and Antibody-Mediated Rejection After ABO-Incompatible Living Related Kidney Transplantation – Is Prophylactic Treatment Necessary?

H. Ishida, T. Kondo, T. Shimizu, T. Nozaki, K. Tanabe.

6:00pm-7:00pm

Preformed Antibodies Against AT₁R and EDNRA Correlate with Rejection Post-Transplant.

A. Gareau,¹ C. Wiebe,^1,2 D. Pochinco,² I. Gibson,³ D. Rush,¹ P. Nickerson.^1,2,4

6:00pm-7:00pm

Prognosis Value of the Presence and Persistence of C1q Binding Anti-HLA Antibodies in Acute Antibody-Mediated Rejection in Kidney Transplantation.

E. Bailly,¹ B. Proust,² M. Giral,³ V. Vuiblet,⁴ V. Chatelet,⁵ E. Morelon,⁶ P. Malvezzi,⁷ S. Caillard,⁸ B. Barrou,⁹ L. Couzi,¹⁰ J. Sayegh,¹¹ C. Mousson,¹² D. Anglicheau,¹³ P. Grimbert,¹⁴ M. Hazzan,¹⁵ G. Mourad,¹⁶ R. Purgus,¹⁷ P. Westeel,¹⁸ Y. Lebranchu,^1,19 M. Büchler.^1,19

6:00pm-7:00pm

Prospective Single Antigen Bead Epitope-Based Clustering for Early Detection of Antibody Mediated Rejection.

A. Lichvar, S. Tremblay, P. Brailey, A. Girnita, R. Alloway, E. Woodle.

6:00pm-7:00pm

Randomized Controlled Trial of Mixed Acute Rejection Therapy in Renal Allografts: 3 Year Follow Up.

A. Leino,¹ A. Lichvar,¹ B. Abu-Jawdeh,¹ A. Govil,¹ G. Mogilishetty,¹ M. Cardi,² J. Kremer,² M. Cuffy,¹ F. Paterno,¹ R. Alloway,¹ A. Shields,^1,2 E. Woodle.¹

6:00pm-7:00pm

Risk of Acute Rejection Among ABO Incompatible Living Donor Kidney Recipients.

P. MacLennan, V. Kumar, R. Reed, D. Mompoint-Williams, K. Stegner, J. Locke.

6:00pm-7:00pm

Tacrolimus as a Tool for Intracellular Assessment of von Willebrand Factor Production by Activated Human Glomerular Endothelial Cells.

S. Béland, P. Vallin, O. Désy, S. De Serres.

6:00pm-7:00pm

The Bacterial Enzyme IdeS, Inhibits HLA Antibody-Mediated NK Cell Activation and Cell Cytotoxicity (ADCC) In Vitro.

S. Ge, M. Chu, J. Choi, S. Jordan, M. Toyoda.

6:00pm-7:00pm

The Coefficient of Variability of Tacrolimus Levels Can Predict Antibody-Mediated Rejection After Renal Transplantation.

P. Ruiz-Esteban,¹ M. Gonzalez-Molina,¹ A. Caballero,² E. Palma,¹ D. Burgos,¹ M. Cabello,¹ J. Alonso-Titos,¹ A. Duarte,¹ D. Hernandez.¹

6:00pm-7:00pm

The Effect of Tocilizmab Treatment (TCZ-Rx) on IgG Subclasses in HLA-sensitized (HS) Kidney Transplant Patients Treated with TCZ.

B.-H. Shin, S. Ge, J. Choi, J. Kahwaji, A. Vo, A. Petrosyan, S. Jordan, M. Toyoda.

6:00pm-7:00pm

The Significance of Microvascular Inflammation in Antibody-Mediated Rejection in ABO-Incompatible Kidney Transplantation.

H. Ishihara,¹ H. Ishida,¹ K. Unagami,² T. Hirai,¹ M. Okumi,¹ K. Omoto,¹ T. Shimizu,¹ K. Tanabe.¹

6:00pm-7:00pm

Tocilizumab as Treatment for Persistent Chronic Active Antibody Mediated Rejection.

H. Fernandez, S. Patel, M. Chiles, L. Ratner, R. Crew.

6:00pm-7:00pm

Treatment of Late Antibody-Mediated Rejection: Observations from Clinical Practice.

G. Einecke,¹ J. Bräsen,² A. Schwarz,¹ H. Haller,¹ F. Njau.¹

6:00pm-7:00pm

Urine IP-10 as the Biomarker for ABMR in Kidney Transplant Recipient with DGF.

N. Townamchai,¹ A. Leelahavanichakul,² J. Supapol,³ S. Wattanatorn,¹ Y. Avihingsanon,¹ K. Praditpornsilpa.¹