2019 American Transplant Congress » Poster Session B: Ischemia Reperfusion & Organ Rehabilition

6:00pm-7:00pm

Activation of Oxidative Stress-Adoptive Responses during Extended Ex Situ Heart Perfusion

S. Hatami, X. Qi, M. Buchko, C. W. White, S. Bozso, S. Himmat, J. Nagendran, D. H. Freed

6:00pm-7:00pm

CD47 Blockade Promotes Hepatic Macrophage Polarization toward M1 during Normothermic Machine Perfusion of Discarded Human Livers

M. Xu¹, F. Zhou¹, S. Garcia-Aroz¹, B. Banan¹, W. Yang², G. Upadhya¹, K. Byrnes³, B. Wong¹, P. Manning⁴, Y. Lin¹, W. Chapman¹

6:00pm-7:00pm

Ceria-Zirconia Nanoparticles as an Enhanced Antioxidant Attenuates Apoptosis of Human Kidney Proximal Tubular Epithelial Cells in Hypoxia

S. Yoon¹, K. Yoon², S. Hong³, S. Yun¹, W. Hwang¹, J. Moon⁴, J. Lee¹, H. Jeon¹

6:00pm-7:00pm

Combined Ischemic and Rapamycin Preconditioning Alleviated Liver Ischemia and Reperfusion Injury by Restoring Autophagy in Old Mice

Z. Rao, X. Pan, W. Zhong, Z. Ding, H. Zhou, C. Liu

6:00pm-7:00pm

Cryopreservation Allows for Extended Graft Survival in a Rat Orthotopic Hind Limb Model

S. A. Fidder¹, B. Oh¹, F. Messner¹, G. Furtmueller¹, K. Helke², E. Greene³, Z. Chen³, L. Campbell³, G. Brandacher¹, K. Brockbank³

6:00pm-7:00pm

Damage-Associated Molecular Pattern Release and Toll-Like Receptor Activation during Cold Storage and Ex Vivo Reperfusion of Old Rat Livers

U. Scheuermann, E. R. Seyferth, M. Zhu, M. Song, J. Yerxa, R. P. Davis, W. Parker, M. Hartwig, J. Kwun, J. Lee, A. S. Barbas

6:00pm-7:00pm

Effects of Omega-3 Fatty Acids on Outcome after Living Donor Right Hepatectomy

S. Lee, J. Kim, G. Choi, J. Joh, S. Lee

6:00pm-7:00pm

Epithelial to Mesenchymal Transition: A Cellular Mediator of Ischemic Cholangiopathy after Liver Transplant

N. A. Wickramaratne¹, R. Li², R. C. Fyffe-Freil², T. Tian², M. J. Mangino²

6:00pm-7:00pm

Erk-elk1-mir-711 Signalling In Cardiac Ischemia Reperfusion Injury In Heart Transplantation

H. Zheng, Y. Su, C. Zhu, V. Veramkovich, X. Zheng

6:00pm-7:00pm

Estrogen Mediated Protection in Renal Ischemia Reperfusion Injury (IRI) is Extrinsic to the Kidney

D. D. Aufhauser¹, S. J. Concors¹, P. T. Hernandez¹, Z. Wang¹, L. Krumeich¹, D. R. Murken¹, G. Ge¹, W. W. Hancock², M. H. Levine¹

6:00pm-7:00pm

Fractalkine is Crucial in Ischemia Reperfusion Injury Related to Acute Rejection in an Allogeneic Heart Transplantation Model

T. Kanzawa¹, D. Tokita¹, T. Yamakawa¹, H. Ishigooka¹, H. Fukuda¹, H. Katsumata¹, S. Miyairi¹, R. Ishii¹, T. Hirai¹, K. Saiga¹, M. Okumi¹, T. Imai², K. Tanabe¹

6:00pm-7:00pm

Histone Deacetylase-8 (HDAC8) Inhibition is Protective in a Murine Model of Renal Ischemia Reperfusion Injury (IRI)

P. T. Hernandez¹, S. J. Concors¹, D. D. Aufhauser¹, L. Krumeich¹, Z. Wang¹, G. Ge¹, A. Beeler², M. Levine¹, W. Hancock³

6:00pm-7:00pm

Hypothermic Machine Perfusion Protects Donation After Cardiac Deathliver Graft Through Gstm1-mediated Cytochrome P450 Exogenous Substance Metabolism Pathway

W. Liang, S. Ye, Z. Zhong, Q. Hu, Y. Wang, Q. Ye

6:00pm-7:00pm

Impact of an Intra-Abdominal Cooling Device during Open Kidney Transplantation in Pigs

A. Longchamp¹, R. P. Meier², N. Colucci³, A. Balaphas³, L. Orci³, A. Nastasi³, G. Longchamp¹, S. Moll⁴, A. Klauser⁵, F. Lazeyras⁵, M. Pascual⁶, J. Corpataux⁷, L. Bühler⁸

6:00pm-7:00pm

Inhibition of TLR4 Mediated Programmed Necrosis Does Not Improve Graft Function and Histology in a Murine Kidney Transplant Model

S. Jain¹, R. Plenter², T. Nydam², A. Jani¹

6:00pm-7:00pm

Ischemia-Free Liver Transplantation Protects Bile Duct from Ischemia/Reperfusion Injury

J. Yang, S. Huang, Z. Zhang, Q. Zhao, W. Ju, Z. Zhu, Y. Tang, L. Wang, Y. Zhang, C. Sun, L. Wu, Z. Guo, X. He

6:00pm-7:00pm

Long Term Cold Ischemia Time in Kidney Transplantation. The Role of Hypothermic Machine Perfusion

G. ADANI¹, U. Baccarani¹, P. Tulissi², C. Vallone², A. Risaliti¹

6:00pm-7:00pm

Metabolic Profiling of Steatotic Human Livers during Ex-Vivo Normothermic Machine Perfusion

S. Raigani¹, N. Karimian², V. Huang², S. Geerts², S. Nagpal², K. Uygun¹, M. Yarmush¹, H. Yeh¹

6:00pm-7:00pm

Microvascular Rarefaction and Long-Term Graft Dysfunction in Kidney Transplant Recipients with Delayed Graft Function

A. Doreille, S. Larivière-Beaudoin, A. Karakeussian-Rimbaud, M. Hébert, M. Dieudé, N. Patey, H. Cardinal

6:00pm-7:00pm

New Reactive Oxygen Species Scavenger Prevents Injury in Ischemia-Reperfusion Injury Model

N. Bath, W. Fahl, R. Redfield III

6:00pm-7:00pm

Normothermic Machine Perfusion of Human Kidneys without an Oxygen Carrier

D. Detelich, C. Eymard, M. Aburawi, C. Carroll, K. Uygun, H. Yeh, J. F. Markmann

6:00pm-7:00pm

Pgc1α Protects against Graft Ischemic Injury and Reduces Alloimmunity

T. J. Borges¹, M. T. Tran², S. Cai¹, N. Murakami¹, A. Uffing¹, M. Uehara¹, E. P. Rhee³, S. M. Parikh⁴, L. V. Riella¹

6:00pm-7:00pm

Phenotype and Course of Renal Tubular Cell Death during Cold Ischemia versus Cold Ischemia Followed by Transplant

S. Jain¹, R. Plenter², T. Nydam², A. Jani¹

6:00pm-7:00pm

Quantitative Proteomics Analysis of Ischemia Reperfusion Injured Liver Tissue Provides Insight into Liver Allograft Quality Evaluation

M. Chen, M. Han, W. Ju, Q. Zhao, D. Wang, Z. Guo, X. He

6:00pm-7:00pm

Role of Mitochondria, Metabolism and Inflammation: Pathways Influencing Short Term Outcomes Post-Renal Transplantation

S. Bontha¹, A. Bajwa¹, G. Lorenzo², J. Eason³, D. Maluf⁴, V. Mas⁵

6:00pm-7:00pm

Sequestration of PLIN2 Regulates High-Fat Diet Induced Metabolic Syndrome and Nonalcoholic Fatty Liver Disease in a Mouse Model of Ischemia Reperfusion Injury

K. Loh¹, X. Liu¹, L. Belyayev¹, C. Albanese², W. Cui¹, T. M. Fishbein¹, K. M. Khan¹, A. Kroemer¹

6:00pm-7:00pm

Stabilization of Cell Junctions Ameliorates the Effects of Brain Death Induced Acute Lung Injury Post-Transplantation

D. P. Allen¹, Z. Tu¹, C. Wallace¹, C. Li¹, J. Kilkenny¹, K. J. Patel¹, D. Nord², S. N. Nadig¹, C. Atkinson²

6:00pm-7:00pm

The Impact of Thrombin / Protease-Activated Receptor-1 Pathway in Hepatic Ischemia-Reperfusion Injury in Mice

D. Noguchi, N. Kuriyama, T. Fujii, H. Kato, M. Kishiwada, S. Mizuno, M. Usui, H. Sakurai, S. Isaji

6:00pm-7:00pm

Transfer of Healthy Mitochondria in Established Ischemic Injury Reduces Progression to Interstitial Fibrosis and Tubular Atrophy

A. Bajwa¹, V. Bontha¹, D. Maluf¹, J. Eason², V. Mas³

6:00pm-7:00pm

Treprostinil Attenuates Renal Ischemia-Reperfusion Injury in Rat

M. Ding¹, E. Tolbert², M. Birkenbach³, C. Chung⁴, R. Gohh⁵, F. Akhlaghi¹, N. Ghonem¹