2020 American Transplant Congress » Poster Session B: Antigen Presentation / Allorecognition / Dendritic Cells

3:30pm-4:00pm

A Bioinformatics Pipeline for the Identification of Crucial Factors for Transplant Rejection Based on NGS Data

J. Vetter¹, A. Heinzel², C. Aschauer², R. Reindl-Schwaighofer², K. Jelencsics², K. Hu², R. Oberbauer², S. Winkler¹, S. Schaller¹

3:30pm-4:00pm

Evaluating Preformed Donor HLA Reactive T Cells Using PIRCHE-II Algorithm

T. Tomosugi¹, K. Iwasaki², S. Sakamoto¹, A. Kanda¹, K. Futamura¹, M. Okada¹, T. Hiramitsu¹, N. Goto¹, S. Narumi¹, Y. Watarai¹, T. Kobayashi², M. Niemann³, E. Spierings⁴

3:30pm-4:00pm

HLA Cross-Dressing of Dendritic Cells by Maternal Exosomes is Associated with PD-L1 Expression in Newborns

D. Lema¹, S. Kanaan², J. Nelson², W. Burlingham¹

3:30pm-4:00pm

Human Live Donor Liver Transplantation is Associated with Pd-l1 Expression on Donor-Exosome-Acquiring Host Dendritic Cells

D. Lema, E. Jankowska-Gan, D. Al-Adra, W. Burlingham

3:30pm-4:00pm

IL-10 Exposure Enhances IRAK-M Expression to Promote Endotoxin Tolerance and the T Cell Tolerogenic Potential of Liver Conventional DCs

Y. Zheng, R. Nakano, A. Thomson

3:30pm-4:00pm

Influence of Microbial Communities on Transplantation

K. Janek¹, J. Fechner¹, K. Krautkramer², S. Sudakaran³, J. Denu⁴, J. Handelsman³, F. Rey⁵, E. Vivas⁵, J. Mezrich¹

3:30pm-4:00pm

Intra-Lymph Node Injection of Rapamycin-Alloantigen Microparticles Regulates Dendritic Cell Antigen Presentation

C. M. Paluskievicz¹, Y. Xiong¹, W. Piao¹, M. Willson-Shirkey¹, H. Eppler², C. M. Jewell², J. S. Bromberg¹

3:30pm-4:00pm

Myeloid Derived Suppressor Cells Expanded by Granulocyte-Colony Stimulating Factor Prolong Allogeneic Cardiac Graft Survival When Compared with MDSCs Expanded by Different Means

Y. S. Lee, T. Zhang, J. S. Bromberg, J. R. Scalea

3:30pm-4:00pm

Next Generation Sequencing Based Analysis of the T-Cell Receptor Repertoire Reveals an Increase of Alloreactive T-Cell Clones after Kidney Transplantation

C. Aschauer¹, K. Jelencsics¹, K. Hu¹, R. Reindl-Schwaighofer¹, J. Vetter², A. Heinzel¹, A. Kainz¹, G. Gualdoni¹, S. Schaller², S. Winkler², R. Oberbauer¹

3:30pm-4:00pm

Pleural Exosome Mediated Donor Antigen Trafficking Into Mediastinal Lymph Nodes Represents a Novel Pathway of Recipient T Cell Activation in Lung Transplantation

A. Habertheuer¹, A. Japp², C. Ram³, S. Chatterjee⁴, S. Rostami², L. Korutla⁵, T. Ochiya⁶, A. Naji², D. Kreisel⁷, P. Vallabhajosyula⁵

3:30pm-4:00pm

T Cells from Highly Sensitized Kidney Transplant Patients Display Distinct TCR Repertoires

S. Negi¹, M. Li¹, A. Rutman², S. Paraskevas¹, C. Polychronakos¹, J. Tchervenkov¹

3:30pm-4:00pm

The Role of Antigen Presentation in B Regulatory Cell Function

A. Cuenca¹, N. Feeney², K. Deng², Q. Fu², G. Huai², C. Rickert², K. Lee², J. Markmann²

3:30pm-4:00pm

Unique Podocyte and Multiplex Single-Cell RNASeq Analysis of Paired Sera and Bone Marrow Samples Suggest a Role for Perturbed Hematopoeitic Progenitors in FSGS Recurrence

P. Rashmi, T. Sigdel, A. Alica Da Silva, R. Paul, D. Galligan, J. Wolfe, F. Vincenti, M. Sarwal