2016 American Transplant Congress » Concurrent Session: Challenges to Graft Survival and Tolerance: Animal Models

Date: Monday, June 13, 2016

Time: 4:30pm-6:00pm

Location: Room 306

Session Type: Concurrent Session

Meeting: 2016 American Transplant Congress

4:30pm-4:42pm: CD4 T Cell Mediated Help Is Required for Intra-Allograft Proliferation of Endogenous Memory CD8 T Cells and Their Ability to Mediate Rejection of Cardiac Allografts Subjected to Prolonged Ischemia.

H. Tsuda, T. Tanaka, C. Su, A. Valujskikh, R. Fairchild.

4:42pm-4:54pm: Absence of Receptors for C3a or C5a Prevent Alloreactive CD8 T Effector Cell (Teff) Expansion but Differentially Impact Memory (Tmem) Persistence Posttransplantation.

D. Mathern, P. Heeger.

4:54pm-5:06pm: Combined CD122 and Costimulation Blockade Prolongs Allograft Survival by Controlling Expansion and Effector Function of Memory CD8 T Cells.

D. Mathews,¹ Y. Dong,¹ L. Higginbotham,¹ S. Kim,¹ C. Breeden,¹ J. Tso,² A. Adams.¹

5:06pm-5:18pm: Ageing as a Barrier to Transplant Tolerance.

J. Kim, R. Stott, H. Deirawan, L. Kojima, L. Washburn, G. Zhao, H. Yeh, J. Markmann.

5:18pm-5:30pm: Enhanced IL-6 Production Impedes Transplant Tolerance Induction in Lupus-Prone Mice.

B. Stocks, C. Wilson, M. Seto, A. Marshall, D. Moore.

5:30pm-5:42pm: Abrogating Donor-Derived Myd88 Signaling Impairs the Recruitment of Recipient Neutrophils and CD8 T Cells into Lung Allografts in Mice.

Z. Zheng,¹ J.-J. Wang,¹ X. Yeap,¹ X. Kang,¹ Y. Xie,¹ X. Luo,² Z. Zhang.¹

5:42pm-5:54pm: Fecal Microbiota Transplant Results in Durable Changes to Host Microbiota That Correlate with Allograft Outcome.

C. Brinkman, L. Hittle, W. Fricke, E. Mongodin, J. Bromberg.

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