2021 American Transplant Congress » Biomarkers, Immune Assessment and Clinical Outcomes

Date & Time:
None. Available on demand

Location: Virtual

Session Type: Poster Abstract

Meeting: 2021 American Transplant Congress

A Reliable Non Invasive Alternative to Surveillance Renal Allograft Biopsy

R. Jain, S. Thaduri, V. Kumar, C. Kew, B. Julian, G. Towns, S. Ong, F. Ahmed, S. Mehta, G. Agarwal
AlloMap Kidney Gene Expression Profiling Discriminates Rejection from Immuno-Quiescence in Renal Transplant Recipients

E. Akalin¹, A. Djamali², H. Xu³, X. Jin³, R. N. Woodward³, S. Dholakia³, J. S. Bromberg⁴
Analysis of Single Cell RNA Sequencing Data to Define Biomarkers of Human Liver Immune Tolerance

B. Rocque¹, A. Barbetta¹, P. Singh¹, C. Goldbeck¹, D. G. Helou², E. Loh³, N. Ung⁴, J. S. Lee⁴, O. Akbari², J. Emamaullee¹
Analysis of the Difference of the Monitoring Results of Tcr High Variable Area in Renal Transplant Recipients After Treatment with Different Immune Induction Schemes

P. Tian, F. Han, M. Dou, B. Zheng, G. Deng, X. Ding, W. Xue
Association of Immune Cell Markers with Adverse Outcomes in the First 6 Months Post-pediatric Heart Transplantation

J. Chen¹, D. Salerno², H. Corbo¹, S. Shah³, A. Rothkopf⁴, I. D. Lytrivi⁴
Biomarkers of Kidney Injury and Repair in Expanded-Criteria Deceased Donor Kidney Transplant Recipients: A Prospective Study

A. Al Jurdi¹, O. Efe¹, B. Aoyama², M. Lima², H. Silva², I. Schmidt³, S. Waikar³, V. Sabbisetti⁴, L. V. Riella¹
Blood Gene Expression and Donor-derived Cell Free DNA for Diagnosing Subclinical Acute Rejection in Stable Kidney Transplant Recipients

S. Park¹, K. Guo², H. Raymond³, E. Poggio⁴, D. Taber⁵, C. Marsh⁶, S. Kurian⁷, S. Kleiboeker⁸, J. Weems⁸, J. Holman⁹, L. Zhao², R. Sinha⁸, S. Brietigam², C. Rebello², M. Abecassis¹⁰, J. Friedewald¹
Brain Natriuretic Peptide and Pedometer Activity are Most Predictive of Poor Kidney Transplant Waitlist Outcomes

P. Manay¹, P. TenEyck², R. Kalil³, M. Sanders⁴, M. Swee⁴, G. Binns⁵, J. Hornikel⁵, D. Katz¹
Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the US

K. A. Agarwal¹, H. Patel¹, N. Agrawal¹, F. Cardarelli¹, N. Goyal²
Cellular and Genetic Signatures of Operational Tolerance in Kidney Transplant Recipients Through Single Cell R N A Sequencing Analysis

H. BAE¹, H. Lee², J. Ryu³, B. Chung², E. Oh³
Characteristics, Risk Factors, and Outcomes of Neutropenia for the First Year After Liver or Kidney Transplantation in Children

C. Jarasvaraparn¹, S. Choudhury², C. Rusch², K. Liss¹, J. Stoll¹, S. Hmiel³, S. Kulkarni¹
Combined Donor Derived Cell Free DNA (AlloSure) and Peripheral Immune Cell Gene Expression (AlloMap) Testing for the Diagnosis of Rejection in Kidney Transplant Recipients with De Novo Donor Specific Antibodies

K. R. Degner, S. Parajuli, F. Aziz, N. Garg, D. Mandelbrot, M. Mohamed, K. Van Hyfte, S. R. Reese, N. A. Wilson, A. Djamali
Comparative Proteomics Analysis Identifies the Biomarker of Ischemia-Reperfusion Injury During Liver Transplantation

M. Chen¹, L. Xiaohong², H. Xitao¹, J. Weiqiang¹
Comparison of Donor-derived Cell Free Dna Between Recipients with First Solitary Allograft and Regrafts

S. Paluri¹, S. Muthusamy¹, M. Shinbashi¹, G. Gupta¹, B. Dale², Z. Kashi³, P. Halloran⁴, D. Kumar¹
Comparison of Next Generation Sequencing Donor-derived Cell Free DNA Assay Utilizing Whole Genome Sequencing

N. Singh¹, M. S. Naseer¹, D. Aultman², H. Shokouh-Amiri², G. Zibari²
Continuation of Immunosuppression After the First Renal Allograft Failure Impacts Panel Reactive Antibody Status During Subsequent Renal Transplantation

J. Patel¹, S. Ali², M. L. Sanders³, C. P. Thomas³, D. Axelrod³, M. Bilal⁴, E. H. Field⁴, S. Kuppachi³
Core Signature of Rejection-Specific Cytokines and Chemokines in Heart Biopsies After Transplantation

L. M. Radomsky¹, Y. Scheibner², J. F. Kuehne¹, J. Keil¹, K. Beushausen¹, K. Ludmilla², A. Schick², F. Ius², G. Warnecke³, C. Bara², C. S. Falk¹
De Novo Donor Specific Antibodies After Heart Transplantation in Fontan Patients with Protein Losing Enteropathy

D. A. Magnetta¹, V. Hoch², D. Pinelli³, M. Monge⁴, E. Pahl¹, P. T. Thrush¹
Dietary Intake and Mycophenolate Mofetil-related Diarrhea Following Kidney Transplantation

G. Onyeaghala¹, L. Teigen², B. Guo², Y. Doronin¹, M. Al-Kofahi², B. Wu², W. Guan², C. Staley², S. Riad², A. Matas², R. Remmel², W. Oetting², C. Dorr¹, P. Jacobson², A. Israni¹
Does the Timing of Subclinical Acute Rejection After Kidney Transplant Matter?

P. Portocarrero¹, S. Park², K. Guo³, L. Zhao³, J. Friedewald²
Donor Derived Cell-free-dna (dd-cfdna) as a Surrogate Marker for Kidney Biopsy- Indiana University Transplant Nephrology Experience

S. Valavoor¹, A. Sharfuddin², G. William³, M. Yaqub¹, D. Mishler¹, O. Adebiyi²
Donor-Derived Cell-Free DNA Performance Characteristics are Similar for Repeat and Primary Kidney Transplant Recipients

V. R. Peddi¹, S. Akkina², S. C. Jordan³, W. Tian⁴, Y. Qazi⁵
Dysregulation of Immune Cell Glycolysis and Oxidative Phosphorylation Correlates with Development of Pre-liver Transplant Immune Dysfunction and Post-transplant Mortality

G. Panayotova¹, L. Jin¹, A. Lemenze¹, S. Simonishvili¹, Y. Qin¹, L. Minze², G. Dikdan¹, F. Paterno¹, X. C. Li², M. Ghobrial², J. V. Guarrera¹, K. E. Lunsford¹
Endothelial Glycocalyx Shedding is Associated with Graft Quality During Ex Vivo Lung Perfusion

K. Noda, B. J. Philips, T. Harano, J. D. Luketich, P. G. Sanchez
Estimated GFR by Serum Myo-inositol, Valine, Creatinine, and Cystatin-c Outperforms Current CKD-epi Equations in Renal Transplant Recipients

J. W. Meeusen¹, F. Stammler², J. Lieske³, M. Grassi², M. Shah⁴, E. Schiffer²
Evaluation of Meningococcal Vaccine Response Among Solid Organ Transplant Recipients Receiving Eculizumab

R. Arora¹, C. Kane¹, K. Cunningham¹, M. Ison²
Evaluation of Serum Klotho Levels at Early Kidney Post-Transplant

T. Vazquez-Sanchez¹, J. Alonso-Titos¹, M. Sánchez-Niño², E. Sola¹, M. Leon³, V. Lopez¹, P. Ruiz-Esteban¹, E. Porrini⁴, A. Ortiz⁵, D. Hernández¹
GENiE in a Bottle – Renasight Testing in the Kidney Transplant Setting – A Single Center Experience

Y. A. Qazi¹, W. Mon¹, N. Ioannou², M. Smogorzewski¹
Gene Expression Profiles Assessed by the Nanostring nCounter® Platform May Differentiate Different Types of Rejection, and Importantly, T-Cell Mediated Rejection from BK Virus Nephropathy

K. R. Degner¹, K. J. Swanson¹, S. Parajuli¹, D. Mandelbrot¹, N. Garg¹, F. Aziz¹, M. Mohamed¹, W. Zhong¹, L. Ptak¹, N. A. Wilson¹, R. Woodward², A. Djamali¹
Hla-dq Epitope Mismatch Predicts De Novo Donor-Specific Antibody Formation and Acute Cellular Rejection After Living Donor Liver Transplantation

K. Ono, K. Ide, Y. Tanaka, M. Ohira, H. Tahara, N. Tanimine, S. Akimoto, Y. Imaoka, K. Sato, H. Yamane, N. Tsukiyama, R. Ide, T. Mochizuki, H. Ohdan
Identification and Validation of a Prognostic Index for Renal Allograft Survival Based on the Geo Database

X. Zhang, Z. Wang, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu
Immunosuppression Impacts Panel Reactive Antibody Status in Second Solid Organ Transplant Recipients – A Single Center Experience

J. Patel¹, S. Ali², M. L. Sanders¹, C. P. Thomas¹, D. Axelrod¹, M. Bilal³, E. H. Field³, S. Kuppachi¹
Immunosuppression is Not Associated with High-risk Immunologic Parameters in Transplant Recipients with the Sars-cov2 Virus

S. Merl, R. Jones, B. Shonts, D. Rust, M. Sykes, J. Weiner
Impact of Deceased Donor Mode of Death and Kidney Donor Profile Index on Baseline Donor Derived Cell Free DNA in Kidney Transplant Recipients

B. Chopra, A. Grazier, K. K. Sureshkumar
Incidence of Pancreatic Exocrine Insufficiency in Patients Undergoing Liver Transplantation

J. Klein¹, M. Rangel¹, I. Ifearulundu¹, Y. Gely¹, Z. Spigel², S. Janardhan³, M. Hertl¹, E. Chan¹
Initial Experience with Trugraf^Tm Gene Expression Profile and Trac^Tm Dd-cfdna Testing in Kidney Transplant Recipients Suggests Synergy and Enhanced Management within the First Year Post-transplant and Beyond

V. Paramasivam, B. Greco, M. Germain
Intraoperative Fluid Management and Kidney Transplantation Outcomes: A Retrospective Review

M. W. Harbell¹, M. B. Kraus¹, S. A. Buckner Petty², J. W. Harbell³
Is Subclinical Allograft Rejection by 2019 Banff Criteria Associated with Worse Kidney Allograft Outcomes? Comparison Between 2007 and 2019 Banff Criteria

M. T. Victor¹, S. Park², K. Guo¹, L. Zhao¹, J. Friedewald³
Kidney Graft Biopsy for Indication Proteinuria: Finding, and Outcomes

S. Parajuli, K. Swanson, J. Alstott, F. Aziz, N. Garg, W. Zhong, A. Djamali, D. Mandelbrot
Kidney Injury in Hematopoietic Cell Transplant (HCT) Recipients: Urinary Biomarkers to the Rescue

T. Salinas¹, C. Snopkowski¹, C. Li¹, K. Chen¹, M. Lubetzky¹, S. Salvatore¹, K. Van Besien¹, E. Jaimes², S. Hingorani³, S. Seshan¹, T. Muthukumar¹
Leukopenia in the Renal Transplant Population

A. Johnson¹, G. Karadkhele², C. Larsen¹
Long-term Outcomes of Early Steroid Withdrawal (SW) After Kidney Transplant

D. Vock¹, A. Matas²
Longitudinal Surveillance, Relative Change Value (RCV) Improve Diagnostic Test Accuracy (DTA) of Donor-Derived Cell Free DNA (dd-cfDNA)

S. Anand, F. Lopez-Verdugo, J. Sanchez-Garcia, L. Dong, M. Fife, J. Krong, D. Morris, T. Srinivas
Longitudinal Variance of Donor Derived Cell Free DNA (dd-cf DNA) in Stable Kidney Transplant (Tx) Patients are Influenced by Donor/Recipient Variables

S. Anand, F. Lopez-Verdugo, J. Sanchez-Garcia, L. Dong, M. Fife, J. Krong, D. Morris, T. Srinivas
Nomogram of Quantity of Peripheral Cxcr5⁺Cd8⁺ T Cells, Aims to Predict Risk of De Novo Dsa in First-time Kidney Transplant Recipients

J. Zimmerer¹, M. Abdel-Rasoul², G. Bumgardner¹
Nonadherence Post-kidney Transplant is Associated with Increased Immune Activation Detected by Peripheral Blood Gene Expression Assay

N. Singh¹, A. Palermini¹, M. S. Naseer¹, T. Le¹, S. Tandukar¹, D. Aultman², H. Shokouh-Amiri², G. Zibari²
Nrf2 Assessment in Discarded Liver Allografts: A Role in Allograft Function and Salvage

O. Ahmed, M. Xu, F. Zhou, A. N. Wein, G. Upadhya, Y. Lin, W. Chapman
Outcomes of Novel Coronavirus 2019 in Solid Organ Transplant Recipients: Yet Again, Race and Payor Status Matters

C. Huang¹, M. Hemmersbach-Miller¹, M. Goss², N. Moreno³, A. Rana¹, J. Goss¹, N. Galvan¹
Precision Medicine in Renal Transplantation: T-cell Repertoire Sequencing to Define Donor-specific Clones for Post-transplant Monitoring

K. R. Sherwood¹, P. Wong¹, F. Fenninger¹, V. Wu¹, J. Beckrud², D. P. Cina³, L. Allan², J. Lan², P. A. Keown²
RNA Sequencing (RNAseq) Tissue Analysis Can Provide Early Warning Signals for Potential Intestinal Transplant Complications

J. Kang¹, L. Belyayev¹, O. Aguirre¹, K. Khan¹, Y. Gusev², K. Bhuvaneshwar², H. Ressom³, J. Hawksworth¹, C. Matsumoto¹, T. Fishbein¹, A. Kroemer¹
Real-time Donor-derived Cell-free Dna Kinetics Indicate Decreased “Molecular Injury” During Treatment of Acute Renal Allograft Rejection

R. Hinojosa¹, K. M. Hitchman², D. J. Ross³, R. C. Hall¹, J. E. Nelson¹, E. L. Kincaide¹, K. Klein¹, A. M. Bell³
Remote Monitoring Using Mobile Phlebotomy and Donor-derived Cell-free DNA in Kidney Transplant Recipients During the Covid-19 Pandemic

N. Ali¹, J. Miles², V. Tatapudi¹, R. Montgomery¹
Renal Tubular-cell-specific Urinary Extracellular Vesicles: A Novel Biomarker for Diabetic Nephropathy After Kidney Transplantation

N. Eguchi¹, H. Lau¹, F. Zaldivar², U. G. Reddy³, E. Tantisattamo³, A. Ferrey³, D. Dafoe¹, H. Ichii¹
Role of Trugraf Testing in Kidney Allografts Previously Biopsied for Dysfunction

Y. A. Qazi¹, W. Mon¹, C. Choi¹, S. Qazi², M. Smogorzewski¹
Should We Worry About Covid-19 Infection in Pediatric SOT?

U. Ekong¹, S. Paul¹, S. Royal², J. Chahine³, N. Yazigi¹, S. Kaufman¹, K. Khan¹, C. Matsumoto¹, A. Kroemer¹, T. Fishbein¹
Single Center Experience Comparing Two Clinically Available Donor Derived Cell Free DNA Tests

S. Bunnapradist¹, S. Lee², P. Homkrailas³, G. Danovitch³
The Assesment of Pre-transplant Donor-reactive IL-21 Producing T Cells as a Tool to Identify Patients at Risk for Acute Rejection

A. Mendoza Rojas¹, T. van Gelder², R. de Kuiper¹, D. Reijerkerk¹, M. C. Clahsen-van Groningen³, D. A. Hesselink¹, C. C. Baan¹, N. M. van Besouw¹
The Impact of Maintenance Immunosuppression Withdrawal on Sensitization Status After Renal Graft Failure

R. Hod Dvorai, A. Almonte, C. Hubbell, M. Laftavi, R. Shahbazov, R. Saidi, O. Pankewycz, J. Leggat, M. Hanlon, B. Gallay
The Role of the B2 Microglobulin Trend in Patients with Delayed Graft Function After Kidney Transplant

A. Perez-Gutierrez, P. J. Bachul, B. Juengel, P. Witkowski, D. DiSabato, R. Barth, J. Fung, Y. Becker
Torque Teno Virus Load Predicts Allograft Rejection but Not Viral Infection After Kidney Transplantation; A Cohort Joint Modelling Study

A. L. van Rijn¹, H. F. Wunderink², I. A. Sidorov¹, C. S. de Brouwer¹, A. C. Kroes¹, H. Putter³, A. P. de Vries⁴, J. I. Rotmans⁴, M. C. Feltkamp¹
Tru and Sure -A Tale of Two Cities! Can Allosure Predict and Enhance Trugraf Results?

Y. A. Qazi¹, W. Mon¹, S. Qazi², C. Choi¹, M. Smogorzewski¹
Trugraf Gene Expression Testing Can Discriminate Rejection in the Setting of Acute Kidney Injury

N. Singh¹, M. S. Naseer¹, D. Aultman², H. Shokouh-Amiri², G. Zibari²
Urinary Exosome Mrna Signature for the Diagnosis of Human Kidney Transplant Rejection

R. El Fekih¹, J. Hurley², V. Tadigotla², A. Alghamdi³, A. Srivastava⁴, C. Coticchia², J. Choi¹, H. Allos⁵, k. yatim⁵, J. Alhaddad⁵, S. Eskandari⁵, P. Chu⁵, A. Mihali⁵, I. Lape⁵, M. Lima Filho⁵, B. Ayoma⁵, A. Chandraker⁵, K. Safa⁶, J. Markmann⁶, L. Riella⁶, R. Formica⁷, J. Skog², J. Azzi⁵

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