ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Real Time Assessment of Kidney Transplant Indication Biopsies by Microarrays: First Results of the INTERCOMEX Study.

    P. Halloran,1,2 J. Reeve,1 INTERCOMEX Study Group.

    1University of Alberta, Edmonton, Canada; 2ATAGC, Edmonton, Canada.

    Oncology uses central molecular tissue assessment (MTA) to guide management but the potential of this approach in transplantation is not known. We undertook a prospective…
  • 2016 American Transplant Congress

    Intervention Development for the Allocation System Changes for Equity in kidNey Transplantation (ASCENT) Study.

    K. Smith,1 J. Gander,1 M. Basu,1 S. Pastan,1 S. Mohan,2 C. Escoffery,1 L. Plantinga,1 S. Kalloo,2 G. Green,3 A. Berlin,4 G. Renville,5 T. Browne,6 N. Turgeon,1 S. Caponi,7 J. Krisher,8 R. Patzer.1

    1Emory University, Atlanta, GA; 2Columbia University, New York, NY; 3American Association of Kidney Patients, Tampa, FL; 4Southeastern Kidney Transplant Coalition, Atlanta, GA; 5National Kidney Foundation, Atlanta, GA; 6University of South Carolina, Columbia, SC; 7ESRD Network 2, Lake Success, NY; 8ESRD Network 6, Raleigh, NC.

    Background: Recent changes in the kidney allocation system (KAS) are expected to reduce racial disparities in kidney transplantation (KTx). However, dialysis facilities may not be…
  • 2016 American Transplant Congress

    Enhanced Recovery After Kidney Transplantation: 48 Hour Length of Stay in Living and Deceased Donor Transplant Recipients.

    O. Ojogho, J. Mejia, S. Bani-Hani, B. Dieter, R. Carson.

    Kidney Transplant Program, Providence Sacred Heart Medical Center and Chldren's Hospital, Spokane, WA.

    BACKGROUND: Enhanced recovery after kidney transplantation is a desired outcome with potential value-enhancing benefits of reduced length of stay (LOS), costs, and risk of nosocomial…
  • 2015 American Transplant Congress

    Rejection Triggers Liver Transplant Tolerance: Involvement of Mesenchyma-Meidated Immune Control Mechanisms

    M. Morita, D. Joyce, C. Miller, J. Fung, L. Lu, S. Qian.

    Immunology, Lerner Research Institute; 2General Surgery, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH.

    Successful organ transplantation relies on lifelong immunosuppression, associated with severe side effects. Induction of tolerance is ideal but elusive in clinic. Indeed spontaneous liver transplant…
  • 2015 American Transplant Congress

    Conditioning of Mesenchymal Stromal Cells With mTOR Inhibitor Enhances Regenerative Properties of Secretome and Attenuates Vascular Calcification

    B. Hegner,1 C. Kurth,1 T. Schaub,1 C. Lange,2 D. Dragun.1

    1Clinic for Nephrology and Intensive Care Medicine, Charité University Hospital, Berlin, Germany; 2Department of Cell and Gene Therapy, University Medical Center Eppendorf, Hamburg, Germany.

    Similar to patients with chronic kidney disease, recipients of kidney transplants are a high-risk population for cardiovascular events due to arterial media calcification in particular…
  • 2015 American Transplant Congress

    Exercise Therapy Improves Body Composition Change After Kidney Transplantation

    M. Miura, H. Higashiyama.

    Department of Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.

    Objectives: Long-term graft and patient survival after kidney transplant is affected by metabolic disorders such as hypertension, obesity and diabetes. The aim of this study…
  • 2015 American Transplant Congress

    Dual PI3K-mTOR Inhibition on Human T Cell Activation, Proliferation, and Differentiation: The First Step in the Development of New Immunosuppressants

    V. Vilchez,1 A. Castellanos,1 D. Butterfield,3 M. Mitov,3 C. Hoopes,1 F. Marti,2 R. Gedaly.1

    1Department of Surgery - Transplant Section, University of Kentucky, Lexington, KY; 2Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, KY; 3Free Radical Biology in Cancer Shared Resource Facility, University of Kentucky, Lexington, KY.

    Background: Regulatory T lymphocytes (Tregs) contribute to transplant tolerance. We have demonstrated that the inhibition of PI3K-mTOR pathway has a major role in the differentiation…
  • 2015 American Transplant Congress

    Arteriovenous Fistulas/Grafts for Patients With Intestinal Failure: Innovation or Insanity?

    G. Vrakas, A. Vaidya, J. Gilbert.

    Oxford University Hospitals, Oxford, United Kingdom.

    Introduction: Vascular access is the lifeline for chronic intestinal failure patients who are dependent on parenteral nutrition. The traditional use of long term tunnelled central…
  • 2015 American Transplant Congress

    Frailty and Length of Stay in KT Recipients

    M. McAdams DeMarco, E. King, X. Luo, L. Kucirka, N. Desai, N. Dagher, B. Lonze, R. Montgomery, D. Segev.

    Johns Hopkins, Baltimore.

    BACKGROUND: In KT recipients, length of stay (LOS) is associated with early hospital readmission; yet, predictors of KT LOS are unclear.METHODS: Registry-based predictors of KT…
  • 2015 American Transplant Congress

    “2mm” Is Reasonable and Feasible Cutoff Value of Indication for Vascular Reconstruction in a Kidney Allograft With Multiple Arteries

    D. Iwami, K. Morita, H. Sasaki, Y. Oishi, H. Higuchi, N. Shinohara.

    Urology, Hokkaido University, Sapporo, Hokkaido, Japan.

    Introduction: Multiple renal arteries are found in 18 to 43% of donor kidneys. We've been using cutoff diameter of <2mm for accessory arteries measured by…
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