2017 American Transplant Congress

April 29-May 3, 2017 in Chicago, IL

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M1 Macrophage-Induced Loss of KLF15 Promotes Chronic Podocyte Injury.

S. Han,^1,2 Y. Kim,¹ S. Lee,¹ H. Lee,^1,2 R.-H. Cha,² J. Lee,^1,2 J. Lee,² D. Kim,^1,2 Y. Kim,^1,2 S. Yang.^1,2
Macrophage Specific Deletion of RhoA Inhibits Fractalkine Signaling and Abrogates Chronic Rejection of Cardiac Allograft.

M. Kloc, Y. Liu, W. Chen, X. Li, R. Ghobrial.
Maintenance of the Phenotype and Abundance of Islet-Resident Macrophages Promotes Islet Graft Survival and Appears to Prevent Type 1 Diabetes.

P. Kyriazis, T. Thornley, K. Agarwal, L. Ma, T. Strom, M. Koulmanda.
Malignancy in Patients Undergoing Simultaneous Heart-Liver and Heart-Kidney Transplant.

A. Chin, A. Habertheuer, A. Chou, M. Acker, M. Williams, P. Atluri, C. Bermudez, P. Vallabhajosyula.
Manning the Gap: Using Technology to Reduce Barriers in Access to Renal Transplantation Waiting List Across Dialysis Facilities.

G. Ferreira,¹ K. Bastos,² E. Barbeta,² B. Pereira,² G. Souza,¹ M. de Souza,¹ V. Colares.¹
Maribavir for Treatment of Cytomegalovirus Infections Resistant or Refractory to Ganciclovir or Foscarnet in Solid Organ Transplant Recipients: A Phase 2 Study.

M. Pereira,¹ F. Silveira,² G. Papanicolaou,³ A. Langston,⁴ R. Avery,⁵ A. Wijatyk,⁶ J. Wu,⁶ M. Boeckh,⁷ F. Marty,⁸ S. Villano.⁹
Maternal Risks and Pregnancy Outcomes After Kidney Transplantation: A Single Center Experience.

A. Devresse,¹ C. Jassogne,¹ C. Hubinont,² M. de Meyer,³ M. Mourad,³ E. Goffin,¹ N. Kanaan.¹
Maximizing the Potential of Treg-Based Therapies for Transplant Rejection via Computational Immune-Modeling: Effect of Dose, Timing, and Distribution.

G. Raimondi,¹ A. Arun,¹ O. Dorabiala,² J. Arciero.³
Measles Screening and Vaccination in Solid Organ Transplant Recipients: Adherence to Infectious Disease Community of Practice (IDCOP) Recommendations.

F. Irani,¹ R. Butler,² C. Kovacs.
Measurement of Dissolved Oxygen by ¹⁹F MRI of Microcapsules Implanted IP in Non-Human Primates.

S. Safley,¹ M. Graham,² M. Garwood,³ K. Papas,⁵ B. Weegman,^3,4 G. Barber,¹ E. Lin,¹ J. Leisen,⁷ A. Sambanis,⁶ B. Hering,² C. Weber.¹
Mechanisms of Fibrosis in the Allograft Kidney: RNA-seq Based Analysis Using Formalin Fixed Biopsies.

G. Zeng,² L. Pan,¹ Z. Lyu,¹ Y. Huang,² P. Randhawa.²
Mechanistic Insights by RNA Profiling on Rejecting Vascularized Composite Allotransplants.

H.-Y. Cheng,¹ S.-C. Liu,² C.-F. Lin,¹ L.-Y. Shih,³ F.-C. Wei.^1,2,3
Medical Mistrust, Perceived Racism, and Experiences of Medical Discrimination Among Transplant Patients.

R. Hamoda, K. Lipford, L. McPherson, J. Gander, R. Patzer.
Medication Adherence and Medicare B Coverage Among Transplant Recipients.

S. Boghani, H. Kirkham, Z. Berry, M. Kang.
Medicinal Herb Cordyceps Sinensis Promotes Long-Term Allograft Survival by Tipping the Balance Between CD4+FoxP3+ Tregs and CD8+ Tcm Cells.

Z. Dai,¹ H. Dai.²
MELD Exception Score: LSAM Modeling of a Fixed Floor.

J. Heimbach,¹ R. Hirose,² D. Schladt,³ J. Pyke,³ J. Zeglin,³ S. Leppke,³ J. Lake,⁴ W. Kim.^5,3
MELD-Based Allocation Leads to Inferior Survival After Liver Transplantation.

P. Ritschl, L. Wiering, M. Hippler-Benscheidt, F. Aigner, M. Biebl, M. Schmelzle, K. Kotsch, J. Pratschke, R. Öllinger.
Memory T Cells Are Decreased in Transplant Recipients Deficient in miR-182.

V. Kaul, L. Wei, X. Qu, O. Martinez, S. Krams.
MERTK Mediates Transplantation Tolerance via Inhibition of TBK1 Phosphorylation and IFN-a Production.

L. Zhang,¹ M. DeBerge,² X. Zhang,³ J. Wang,³ Z. Zhang,³ E. Thorp,² X. Luo.^1,2,3
Mesenchymal Stem Cells Suppress T Cell Proliferation and Improve Allograft Survival in a Nonhuman Primate Transplant Model.

S. Kim, D. Mathews, L. Higginbotham, C. Breeden, C. Larsen, A. Adams.
Meta-Analysis of Clinical Significance of Complement Activating Anti-HLA DSA in Kidney Transplantation.

A. Bouquegneau,^1,2 C. Ulloa,¹ O. Aubert,¹ C. Loheac,¹ D. Viglietti,¹ J. Empana,¹ P. Jabre,¹ X. Jouven,¹ C. Lefaucheur,¹ A. Loupy.¹
Metabolomics Study for Identification of Potential Biomarkers of Long-Term Survival in Kidney Transplantation Recipients.

C.-D. Kim, H.-Y. Jung, R.-H. Kim, S.-M. Park, J.-H. Park, K.-H. Lee, E.-S. Lee, K.-Y. Kim, J.-Y. Choi, J.-H. Cho, S.-H. Park, Y.-L. Kim.
MHC Class II-Peptide Complexes Displayed on Activated T Cells Guide Treg Suppression.

M. Fryer, S. Junius, S. Germana, L. Turka, C. LeGuern.
Microarray Analysis of Rejection in Formalin-Fixed Paraffin-Embedded Biopsies: Similarities and Disparities with Conventionally Stabilized Biopsies.

K. Famulski, J. Revee, P. Halloran.
Microcirculation Inflammation in Kidney Allograft Biopsies.

M. Giordani,¹ M. Bedini Rocca,¹ S. Groppa,¹ C. Mombelli,¹ S. Christiansen,² M. Ocampo,¹ G. Rosa Diez,¹ N. Imperiali.¹
MicroRNAs and Long Non-Coding RNAs as Potential Novel Biomarkers in Transplanted Patients with Candida Infection.

A. Yang,¹ C. Zhou,² D. Li,³ W. Ju,¹ Z. Guo,¹ L. Wu,¹ A. Hu,¹ Y. Ma,¹ D. Wang,¹ X. Zhu,¹ X. He.¹
MicroRNAs Differentiate Between Antibody and T-Cell Mediated Renal Allograft Rejection.

T. van den Bosch,¹ M. Clahsen-van Groningen,² F. Rezaee,³ D. Nieboer,⁴ E. Steyerberg,⁴ C. Baan,¹ A. Rowshani.¹
Microvascular Inflammation at 4 Months Posttransplant Is Associated with Transplant Glomerulopathy at One and Two Years Independent of Rejection and Donor Specific Antibodies.

H. Khamash, G. Mour, L. Archambault, M. Buras, H. Kosiorek, M. Pando, K. Reddy, H. Chakkera, J. Huskey, S. Nair, A. Jaramillo, M. Smith, B. Kaplan, R. Heilman.
Minimal Effect of Broader Heart Sharing on Regional Outcomes.

A. Bitar,¹ M. Skeans,² R. Davies,³ M. Farr,⁴ A. Kao,⁵ L. Robbins-Callahan,⁶ J. Rogers,⁷ S. Silvestry,⁸ M. Colvin.^1,2
Minor Degree of Persistent Microscopic Hematuria in Potential Living Kidney Donors Is Associated with Pathology.

V. Kumar,¹ M. Saha,¹ J. Locke,² R. Gaston,¹ M. Hanaway.²
Mitochondrial Dysfunction Is a Common Feature of Injury in Donor Kidneys After Brain and Circulatory Death.

M. Lo Faro,¹ M. Akhtar,¹ H. Huang,¹ M. Kaisar,¹ R. Rebolledo,² K. Morten,¹ L. Heather,¹ A. Dona,³ H. Leuvenink,² S. Fuggle,¹ B. Kessler,¹ C. Pugh,¹ R. Ploeg.¹
Mitochondrial Permeability Can Regulate Endothelial Cell Necroptosis and Promote Cardiac Allograft Rejection.

I. Gan,^1,2 J. Jiang,¹ D. Lian,¹ A. Jevnikar,^1,3 Z.-X. Zhang.^1,2
MMR and Varicella Immunity After Pediatric Liver Transplant.

A. Waugh,¹ A. Opekun,^1,2 F. Munoz,² T. Miloh.²
Model to Predict Prolonged Delayed Graft Function (DGF) Following Kidney Transplantation from Deceased Donor with Acute Kidney Injury (AKI Tx).

R. Heilman,¹ B. Smith,² C. Johnson,¹ H. Khamash,¹ K. Reddy,¹ W. Kremers,² B. Kaplan.¹
Modifiable Deceased Organ Donor Critical Care Parameters Impact Donor Lung Utilization.

A. Spaugy,¹ M. Sally,¹ K. Ellis,¹ T. Groat,¹ M. Patel,² D. Malinoski.¹
Modification of Human Endothelial Cells by CRISPR/Cas9-Mediated Ablation of Class I and II Major Histocompatibility Complex Antigen Expression.

J. Merola, C. Anderson, H. Xu, T. Manes, J. Pober.
Modular Training in Organ Procurement, in the Present Era of High BMI Donors: Validation by Results.

H. Sharma, M.-T. Abraham, I. Al Hasan, B. Al-Harbi, S. Aquil, A. Sener, P. Luke, D. Quan.
Modulating Ischemia-Reperfusion Injuries with Pharmacological Agents: A Bench-to-Bedside Approach.

M. Thomas, G. Tardif, A. Melanger, P. Berna.
Molecular Adsorbent Recirculating System (MARS) Effectively Replaces Hepatic Function in Severe Acute Liver Failure.

S. Hanish,¹ R. Barth,¹ D. Stein,² E.-O. Essien,¹ P. Thurman,² T. Scalea,² S. Bartlett.¹
Molecular Analysis of Acute Rejection in Formalin-Fixed Paraffin-Embedded Clinical Face Transplant Biopsies.

T. Win,¹ B. Dyring-Andersen,¹ V. Barrera,² S. Ho Sui,² R. Lopdrup,¹ H. Kiwanuka,¹ N. Murakami,¹ J. Teague,¹ E. Lowry,¹ E. Bueno,¹ A. Chandraker,¹ L. Riella,¹ B. Pomahac,¹ R. Clark.¹
Molecular Classifier of Antibody-Mediated Rejection Is a Better Predictor of Histologic Rejection Than a Corresponding Transcript Set and Is Further Improved When Combined with Classifiers of Rejection Syndromes.

K. Famulski, P. Halloran.
Molecular Profiles of Renal Allograft Biopsies at 12 Months Post Renal Transplant in Patients Exposed to Low Dose CNI and Everolimus vs. Patients Exposed to Full Dose CNI and MMF.

L. Gallon,¹ J. Leventhal,¹ D. Maluf,² V. Sai Bontha,² A. Shetty,¹ O. Traitanon,¹ M. Ansari,¹ J. Mathew,¹ S. Wongpraphairot,¹ V. Mas.²
Molecular Significance of Peritubular Capillaritis in Early Transplant Kidney Biopsies of Donor-Specific Antibody Negative Patients.

M. Ajaimy, P. O Broin, Y. Bao, E. Akalin.
More Rapid Decline in Male VS Female Living Kidney Donations (LKD) Varies by Income.

J. Lesage, J. Gill, C. Rose, Y. Joffres, J. Gill.
More Than Renal Function: Use of Belatacept to Improve Drug Toxicities.

E. Cohen,¹ B. Knight,³ W. Asch.²
Mouse FCs May Contain Lymphoid Progenitor Cells That Have the Capacity to Generate B and T Cells In Vivo.

A. Chhabra, Y. Wen, Y. Huang, H. Xu, A. Merchak, S. Ildstad.
mRNA Biomarkers in Renal Allograft Protocol Biopsies Detected by the Nanostring Platform Predict Tolerance in Non-Human Primates.

M. Matsunami,¹ T. Oura,¹ I. Rosales,² R.-N. Smith,² B. Adam,³ M. Mengel,³ A. Cosimi,¹ R. Colvin,² T. Kawai.¹
mTOR Inhibition Diminishes Peripheral Blood CD8⁺CD28^–CD38^hi Effector/Memory T Cells and Facilitates Resolution of Belatacept-Refractory Kidney Rejection.

C. Castro-Rojas,¹ A. Godarova,¹ A. Leino,² R. Alloway,² M. Jordan,³ E. Woodle,² D. Hildeman.¹
mTOR Inhibitor and Low-Dose Tacrolimus in Pediatric Kidney Transplant (PKT): 9-Years Data of a Bi-Therapy Treatment.

R. Vilalta, E. Lara, A. Madrid, M. Muñoz, S. Chocron, G. Ariceta.
mTORC1 and 2 Regulate Dendritic Cell (DC) Metabolism and Allostimulatory Function of Donor DCs in Skin Transplantation.

A. Watson,^1,2 H. Dai,^1,3 A. Menk,^4,5 G. Delgoffe,^4,5 A. Thomson.^1,2,3
Multi-Stakeholder Perspectives on the Importance of Outcomes for Trials in Kidney Transplantation: An International Best Worse Scaling Survey.

M. Howell,^1,2 N. Evangelidis,^1,2 B. Sautenet,² G. Wong,^1,2,3 J. Craig,^1,2 K. Howard,¹ A. Tong.^1,2
Multicenter Validation of a Clinicopathologic Risk Score to Predict Hepatocellular Carcinoma Recurrence Following Liver Transplantation: Analysis of 4984 Patients from the US Multicenter HCC Transplant Consortium.

V. Agopian, On Behalf of the US Multicenter HCC Transplant Consortium.
Multidisciplinary Psychosocial Liver Transplant Evaluation in Patients with Alcoholic Liver Disease – Moving Beyond the Six-Month Rule.

K. Wenzke,¹ S. Kelly,² J. Eickhoff,³ M. Lucey,¹ J. Rice.¹
Multiple Dosing of Anti-C1s Antibody TNT009 – Effect on HLA Antibody-Triggered Complement Activation in Healthy Volunteers and Kidney Transplant Recipients with Antibody-Mediated Rejection.

J. Muhlbacher,¹ B. Jilma,² M. Wahrmann,³ F. Eskandary,³ J. Gilbert,⁴ S. Panicker,⁴ G. Böhmig.³
Muscle Mass Is Predictive of Mortality in Obese Renal Transplant Patients.

J. Souweine,^1,3 M. Le Quintrec,¹ I. Szwarc,¹ V. Pernin,¹ G. Mourad,¹ J. Cristol,^2,3 J. Serre.¹
Mutations in Influenza A Virus and Clinical Implications in Transplant Recipients.

V. Ferreira,¹ A. Humar,¹ E. Cordero,² E. Blumberg,³ S. Husain,¹ J. Kalpoe,⁴ M. Multicenter Influenza Group, D. Kumar.¹
Mycophenolate Dose Reductions Are Not Associated with De Novo Donor-Specific Antibodies.

S. Davis, J. Gralla, P. Klem, A. Wiseman, J. Cooper.
Mycophenolic Acid Needs Ca²⁺ to Exert Its Anti-inflammatory Action via Shedding of Toll-Like Receptor4 and Tumor Necrosis Factor Receptor 1.

J. Kim,¹ W. Yang,¹ C. Baek,¹ N. Han,² S.-K. Park.¹
Myeloid HO-1 Orchestrates Liver Graft Function via SIRT1/p53 Signaling: From Mouse-to-Human.

K. Nakamura,¹ M. Zhang,² B. Ke,¹ S. Kageyama,¹ N. Datta,¹ A. Zarrinpar,¹ R. Busuttil,¹ J. Araujo,² J. Kupiec-Weglinski.¹
Myeloid HO-1 Regulates M2 Macrophage Activation in Liver Ischemia-Reperfusion Injury (IRI).

K. Nakamura,¹ M. Zhang,² S. Kageyama,¹ B. Ke,¹ R. Sosa,³ E. Reed,³ A. Zarrinpar,¹ R. Busuttil,¹ J. Araujo,² J. Kupiec-Weglinski.¹
Myeloid-Derived Suppressor Cells (MDSC) Accumulate in Intestinal Transplant (IT) Recipients (rc) and Suppress Recipient T-Cell (T) Response Against Donor Antigen.

S. Okano,¹ D. Kish,² K. Keslar,² W. Baldwin,² R. Fairchild,¹ C. Miller,¹ K. Abu-Elmagd,¹ A. Khanna,¹ M. Fujiki,¹ J. Fung,¹ G. Costa,¹ K. Hashimoto.¹
Myocardial Improvement Six Months After Kidney Transplantation: Non-Contrast Cardiac Resonance Study.

M. Contti, L. Morales-Buenrostro, H. Nga, P. Garcia, M. Barbosa, H. Takase, M. da Silva, A. Moyses.

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