ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Development of a Targeted Genetic Renal Disease Panel With NexGen Sequencing for Unbiased Testing of Living Kidney Donors for Genetic Kidney Disease

    C. Thomas,1 Z. Stewart,3 A. Mansilla,2 S. Mason,2 A. Kwitek,2 C. Campbell,2 R. Smith,1,2 R. Smith.1,2

    1Internal Medicine, University of Iowa, Iowa City, IA; 2Institute of Human Genetics, University of Iowa, Iowa City, IA; 3Surgery, University of Iowa, Iowa City, IA.

    Recent studies indicate that living donors biologically related to their transplant recipient may be at higher risk of ESRD compared to unrelated donors, possibly secondary…
  • 2015 American Transplant Congress

    The Extended Toronto Criteria for Transplantation for Hepatocellular Carcinoma. A Validation Study

    G. Sapisochin, N. Goldaracena, J. Laurence, M. Dib, A. Barbas, A. Ghanekar, L. Lilly, E. Renner, M. Selzner, M. Cattral, I. McGilvray, D. Grant, P. Greig.

    Multi-Organ Transplant, Toronto General Hospital. University of Toronto, Toronto, ON, Canada.

    Liver transplant (LT) listing criteria for patients with hepatocellular cancers (HCC) that exceed the Milan criteria are still controversial. At the University of Toronto, we…
  • 2015 American Transplant Congress

    BAFF Binding to T Cell-Expressed BAFF-R Promotes Follicular Helper T Cell Proliferation and GC B Cell Responses

    M. Chen,1 Q. Li,1 W. Stohl,2 S. Zheng,2 X. He,1 Z. Guo.1

    1Organ Transplant Center, 1st affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; 2Division of Rheumatology and Immunology, University of Southern California, Keck School of Medicine, Los Angeles, CA.

    Recent studies have defined a crucial role for the B cell–activating factor belonging to TNF family (BAFF) in promoting germinal center (GC) responses in mouse…
  • 2015 American Transplant Congress

    Concerted T-Cell Activity Against Early and Late BKV-Antigens Is Necessary for Viral Clearance

    B. Weist,1,2 M. Schmueck,2 M. Dziubianau,2 P. Reinke,1,2 N. Babel.1,2

    1Department of Nephrology, Charite Universitaetsmedizin, Berlin, Germany; 2BCRT, Charite Universitaetsmedizin, Berlin, Germany.

    Polyomavirus-BK (BKV) associated nephropathy is a known cause of graft failure. No specific therapy is established so far and viral load monitoring accompanied by adjustment…
  • 2015 American Transplant Congress

    Utility of Anti-Phospholipase A2 Receptor (Anti-PLA2R) ELISA Testing in Predicting Post-Transplant Idiopathic Membranous Nephropathy (IMN)

    C. VanBeek,1 D. Thomas,2 A. Jimenez,2 A. Vo,2 S. Jordan,2 M. Toyoda.2

    1Pathology, Cedars-Sinai Medical Center, Los Angeles, CA; 2Transplant Immunology, Cedars-Sinai Medical Center, Los Angeles, CA.

    Backgound: IMN is frequently associated with autoantibodies to the podocyte antigen, PLA2R. Anti-PLA2R associated IMN is diagnosed by detecting PLA2R antigen within glomerular immune complexes…
  • 2015 American Transplant Congress

    Combined Robotic Kidney Transplantation and Sleeve Gastrectomy in Obese Recipients: Initial Results from Prospective Randomized Study

    I. Tzvetanov, G. D'Amico, G. Georgiev, H. Jeon, R. Garcia-Roca, E. Benedetti, J. Oberholzer.

    Surgery, Division of Transplantation, University of Illinois at Chicago, Chicago, IL.

    IntroductionIn many transplant centers, patients with a BMI above 40 kg/m2 are either completely excluded or required to lose weight before being considered for kidney…
  • 2015 American Transplant Congress

    Rabbit Antithymocyte Globulin Is Associated With Improved Patient and Graft Survival in Liver Transplantation. Experience With 595 Patients

    M. Montenovo,1 F. Jalikis,2 L. Meng,3 Y. Matthew,2 D. Andre,1 H. Ryan,3 R. Jorge.1

    1Surgery, University of Washington, Seattle, WA; 2Pathology, University of Washington, Seattle, WA; 3Pharmacy, University of Washington, Seattle, WA.

    BACKGROUND: Use of induction therapy in liver transplantation is debatable. We aimed to compare clinical outcomes of different induction protocols in liver transplant recipients.METHODS: Retrospective…
  • 2015 American Transplant Congress

    B Cell MicroRNA as Biomarkers for Epstein-Barr Virus Associated Post-Transplant Lymphoproliferative Disorder

    A. Harris-Arnold, V. Kaul, S. Shaffert, O. Hatton, C. Esquivel, S. Krams, O. Martinez.

    Surgery/Division of Abdominal Transplant, Stanford University School of Medicine, Stanford, CA.

    Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of organ transplantation and is commonly associated with Epstein Barr virus (EBV) infection. EBV viral loads…
  • 2015 American Transplant Congress

    Alemtuzumab Induction Is Associated With Higher Risk of Polyomavirrus Associated Nephropathy (PVAN) in Kidney Transplant Recipients

    H. Wadei,1 H. Saull,2 C. Enderby,2 M. Mai,1 M. Prendergast,1 T. Gonwa.1

    1Transplant, Mayo Clinic, Jacksonville, FL; 2Pharmacy, Mayo Clinic, Jacksonville, FL.

    Incidence of PVAN on protocol kidney biopsies with alemtuzumab induction is unknown.Methods:The 1-year risk of PVAN was retrospectively compared between 200 consecutive primary kidney recipients…
  • 2015 American Transplant Congress

    The Losing Trifecta: Age ≥70, Deceased Donor Transplant, and Delayed Graft Function

    R. Crew, H. Fernandez, S. Mohan, G. Dube, L. Ratner, R. Sandoval, S. Patel.

    Columbia University, New York.

    INTRO: Patients ≥70 are the fastest growing part of the ESRD population. Although historically patients ≥70 have had acceptable renal transplant outcomes, in our own…
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