ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Morphometry of the Epithelial-Mesenchymal Transition (EMT) in Subsequent Biopsies from Transplanted Kidney

    R. Świder, A. Perkowska-Ptasińska, A. Stachurska, J. Fabijańska-Mitek, R. Zagożdżon, S. Gruca, J. Gołąb, M. Durlik.

    Department of Transplantation Medicine, Medical University, Warsaw, Poland; Department of Transplantation Medicine, Medical University, Warsaw, Poland; Department of Immudohaematology, Centre of Postgraduate Medical Education, Warsaw, Poland; Department of Immudohaematology, Centre of Postgraduate Medical Education, Warsaw, Poland; Department of Immunology, Medical University, Warsaw, Poland; Department of Immunology, Medical University, Warsaw, Poland; Department of Immunology, Medical University, Warsaw, Poland; Department of Transplantation Medicine, Medical University, Warsaw, Poland.

    EMT plays the principal role in the pathogenesis of IF/TA as a consequence in the failure of a transplanted kidney. Many facts suggest that the…
  • 2015 American Transplant Congress

    Down-Regulation of Autophagy Correlates With Increased Apoptosis in the Kidney, But Not in the Liver, of Brain Dead Rats

    A. van Erp,1 R. Rebolledo,3 P. Ottens,1 J. Pirenne,2 H. Leuvenink,1 J.-P. Decuypere.2

    1Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Department of Microbiology and Immunology, Catholic University Leuven, Leuven, Belgium; 3Department of Surgery, University of Chile, Santiago, Chile.

    Organs from brain dead donors have inferior quality and show higher rejection rates after transplantation compared to living donors. Brain death (BD) in the donor…
  • 2015 American Transplant Congress

    Short-Term QOL After Live Liver Donation: A New York Center for Liver Transplantation (NYCLT) Report

    D. LaPointe Rudow,1 S. DeLair,2 S. Florman,1 J. Guarrera,3 M. Kinkhabwala,4 M. Orloff,5 Y. Wu,6 L. Teperman.7

    1Mount Sinai Medical Center, New York, NY; 2New York Center for Liver Transplantation, Albany, NY; 3New York Presbyterian Hosptial, New York, NY; 4Montefiore Medical Center, Bronx, NY; 5University of Rochester Medical Center, Rochester, NY; 6Westchester Medical Center, Valhala, NY; 7New York University Hospitals Center, New York, NY.

    Introduction: LDLT is an option for selective patients, especially in regions with less opportunity for deceased donors. New York State (NYS) has the most LDLT…
  • 2015 American Transplant Congress

    Incisional Herniation Following Hand Assisted Laparoscopic Donor Nephrectomy: Incidence, Impact and Aetiology

    Z. Ahmed, I. Mosca, M. Dirix, R. Tamburrini, N. Kessaris, N. Mamode.

    Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom.

    Introduction: Living kidney donor demographics, perioperative outcomes and data on renal function is recorded by national mandate. However other longer term and potentially significant surgical…
  • 2015 American Transplant Congress

    Evaluation of Geographically Distant Living Kidney Donors: A Barrier to Living Donation?

    F. Weng, N. Dhillon, L. Davis, R. Goldberg, A. Patel, K. Tibaldi, M. Morgievich, S. Mulgaonkar.

    Renal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ.

    Introduction: Living kidney donors often live far from the recovering transplant center where they donate. We sought to determine (1) characteristics of these geographically distant,…
  • 2015 American Transplant Congress

    Acute Kidney Injury After Lung Transplantation – Incidence, Risk Factors and Mechanisms

    F. Gueler,1 G. Warnecke,5 M. Peperhove,2 M.-S. Jang,1 C. Schroeder,3 S. Tewes,2 B. Wiese,6 C. Fegbeutel,5 R. Lichtinghagen,7 B. Jüttner,8 F. Wacker,2 D. Hartung,2 B. Akerstrom,4 M. Gram,4 H. Haller,1 A. Haverich,9 K. Hueper.2

    1Nephrology, Hannover Medical School, Hannover, Germany; 2Radiology, Hannover Medical School, Hannover, Germany; 3Proteomics, German Research Cancer Center, Heidelberg, Germany; 4Physiology, Lund University, Lund, Sweden; 5Thoracic and Cardiac Surgery, Hannover Medical School, Hannover, Germany; 6Medical Statistics, Hannover Medical School, Hannover, Germany; 7Laboratory Medicine, Hannover Medical School, Hannover, Germany; 8Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany; 9Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany.

    Background: Acute kidney injury (AKI) is a frequent and severe complication after solid organ transplantation. In a retrospective analysis and afterwards in a prospective clinical…
  • 2015 American Transplant Congress

    Early Weight Gain After Transplantation Can Cause Adverse Effect On Transplant Kidney Function

    S. Choi, I.-K. Kim, S. Son, M. Ju.

    Surgery, Gangnam Severance Hospital, Yonsei College of Medicine, Seoul, Korea.

    Background: Outcomes of kidney transplant recipients with increased body mass index (BMI) remain controversial. We studied the relationship between change of BMI and transplant kidney…
  • 2015 American Transplant Congress

    Clinical Significance of Multidetector Coronary Computed Tomography Angiography to Evaluate the Prevalence and Severity of Coronary Artery Disease in Asymptomatic Kidney Transplantation Recipients

    S. Lee,1 K. Huh,3 B. Kim,2 B. Choi,4 Y. Kim,4 Y. Kim,3 B. Kim.2

    1Surgery, Ajou University School of Medicine, Suwon, Korea; 2Internal Medicine, Yonsei University College of Medicine, Seoul, Korea; 3Surgery, Yonsei University College of Medicine, Seoul, Korea; 4Radiology, Yonsei University College of Medicine, Seoul, Korea.

    Introduction: Coronary artery disease (CAD) is one of the leading causes of mortality in kidney transplant (KT) recipients. Noninvasive coronary angiography using multidetector computed tomography…
  • 2015 American Transplant Congress

    Adoptive Immunotherapy Using Activated NK Cells Ameliorates the FcγRIIIa Gene Polymorphism-Associated Susceptibility to Post Transplant Bloodstream Infection

    S. Shimizu, Y. Tanaka, H. Tazawa, S. Verma, H. Ohdan.

    Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    Background: At ATC 2014, we demonstrated that detection of single nucleotide polymorphisms (SNP) of FcγRIIIa helps predict the susceptibility of liver transplant (LT) recipients to…
  • 2015 American Transplant Congress

    The Use of Systems Biology to Identify Mitochondrial Dysfunction and Metabolic Dysregulation as Targets for Intervention in the Brain Dead Organ Donor

    M. Akhtar, L. Lo Faro, R. Robelledo, M. Kaisar, H. Huang, H. Leuvenink, P. Friend, S. Fuggle, C. Pugh, R. Ploeg.

    Oxford Transplant Centre, University of Oxford, Oxford, Oxfordshire, United Kingdom.

    Introduction: Due to the persistent donor shortage many centres accept older, higher risk organs which have inferior outcomes. Understanding how kidneys are injured during brain…
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