2015 American Transplant Congress
Influence of POR*28 Genotype on Tacrolimus Disposition in Heart Transplant Recipients
Polymorphisms in P450 oxidoreductase (POR) have been shown to modulate CYP3A activity and alter the pharmacokinetics of CYP3A substrates, such as tacrolimus (TAC). The objective…2015 American Transplant Congress
Identification of Genetic Variants Associated With Variation of Tacrolimus Levels in African Americans Using GWAS
African American kidney transplant recipients (AA) have a higher incidence of allograft failure when compared to Caucasians. We have previously reported that tacrolimus troughs (TT)…2015 American Transplant Congress
Immunological Evaluation of Acellular Extracellular Matrix Upon Transplantation
Background : To mitigate the scanty supply of donor organs, porcine tissues can be utilized since, it embrace the potential to accomplish the task of…2015 American Transplant Congress
Microchimerism-Tolerance Missing Link: Exosome Acquisition by Host Dendritic Cells
Surgery, University of Wisconsin, Madison, WI.
Background: widespread maternal microchimerism (MMc) in mice is associated with development of immune regulation, which can be used to predict transplantation tolerance. We recently showed…2015 American Transplant Congress
Donor Dendritic Cells – Potential New Therapeutic Target in Transplantation
Background: It is clear that T cells play a central role in the process of allograft rejection. However, donor dendritic cells (dDC) are the most…2015 American Transplant Congress
Educating the Less Prepared: Transplant Knowledge and Decision-Making Differences by Race at Onset of Evaluation
Racial minorities have higher rates of kidney failure than Whites but are less likely to receive kidney transplants. This study described each race/ethnic groups' level…2015 American Transplant Congress
Validating Outcomes Reported to the Organ Procurement and Transplantation Network for Deceased Donor Kidney Recipients
Data reported to the Organ Procurement and Transplantation Network (OPTN) is used in kidney transplant research, quality metrics and in policy development, but the accuracy…2015 American Transplant Congress
Prospective, 6 Month, Open Label, Conversion Study from Mycophenolate Mofetyl to Mycophenolic Acid Evaluating the Severity of Gastro-Intestinal Symptoms and Mycophenolic Acid Urinary Metabolite as a Surrogate Marker of Plasmatic Area Under the Curve
Introduction: Treatment with mycophenolate mofetil (MMF) often results in adverse gastro-intestinal (GI) events, which can lead to dose reductions that in turn can increase the…2015 American Transplant Congress
Outbreak of Pandemic Influenza A (H1N1pdm) in a Kidney Transplant Unit The Protective Effect of Vaccination
Background: Seasonal influenza vaccination is recommended for patients with end-stage renal disease, although the efficacy of the vaccination among these patients is unknown. We characterize…2015 American Transplant Congress
Deceased Donor HLA Antibody Incompatible Renal Transplantation Without Antibody Removal: High Incidence of Acute Rejection Reduced By T-Cell Depleting Induction Therapy
Aims: Screening for HLA-specific antibodies (Ab) is routine for patients on kidney transplant waiting lists, and HLA antigens to which a patient has detectable Ab…
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