ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Kidney Vs. Heart Calculated PRA (CPRA) for Sensitized Heart Candidates: Does Donor Ethnic Distribution Make a Difference?

    A. Kucheryavaya, L. Robbins Callahan, L. Edwards.

    UNOS, Richmond.

    Background: CPRA, which is used for deceased donor (DD) kidney (KI) and pancreas/kidney-pancreas (PA/KP) allocation, is computed with KI DD HLA and ethnic frequencies. CPRA…
  • 2015 American Transplant Congress

    The Role of the Incretin Effect After Pancreas Transplantation

    S. Mittal,1 R. Franklin,1 E. Sharples,1 F. Knop,2 J. Holst,2 S. Gough,1 P. Friend.1

    1Oxford University Hospital, Oxford, United Kingdom; 2University of Copenhagen, Copenhagen, Denmark.

    AIM: The ability to generate a greater insulin response to an oral compared to an intravenous glucose load is the result of pancreatic stimulation by…
  • 2015 American Transplant Congress

    Early Hospital Readmission After Simultaneous Pancreas-Kidney Transplantation

    E. King,1 L. Kucirka,1 M. McAdams-DeMarco,1,2 A. Massie,1,2 D. Segev.1,2

    1Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD; 2Epidemiology, Johns Hopkins University, School of Public Health, Baltimore, MD.

    Background: Early hospital readmission (EHR) is associated with increased morbidity and mortality after kidney transplantation. However, following simultaneous pancreas-kidney transplantation (SPK), EHR rates are unknown,…
  • 2015 American Transplant Congress

    Effect of Extension in Submucosal Ureteral Tunnel to Prevent Vesicoureteral Reflux and Its Impact on the Graft Survival in Kidney Transplantation

    T. Inoue,1 S. Satoh,2 M. Saito,1 K. Numakura,1 H. Tsuruta,1 S. Akihama,1 S. Narita,1 N. Tsuchiya,1 T. Habuchi.1

    1Urology, Akita University, Akita, Japan; 2Center for Kidney Disease, Akita University, Akita, Japan.

    Objects: It is plausible that vesicoureteral reflux (VUR) induced by an insufficient length of a submucosal ureteral tunnel leads graft function to deteriorate in kidney…
  • 2015 American Transplant Congress

    A Non-Invasive Urinary Common Rejection Module (uCRM) Gene Expression Score Enables Accurate Discrimination of Acute Rejection in Kidney Transplant Patients

    O. Bestard,1,2 T. Sigdel,1 Y. Ng,1 S.-C. Hsieh,1 S. Roedder,1 N. Dvorak,1 T. Tran,1 M. Sarwal.1

    1Department of Transplant Surgery, UCSF, San Francisco, CA; 2Kidney Transplant Unit, Bellvitge University Hospital, Barcelona, CAT, Spain.

    A common rejection module (CRM) consisting of 11 genes expressed on allograft biopsies was recently shown to be highly accurate to discriminate patients undergoing acute…
  • 2015 American Transplant Congress

    Alterations in Peripheral Blood B Cell Subpopulations in Kidney Transplant Recipients With DSA

    B. Ramaswami,1 R. Ippolito,2 B. Elinoff,1 M. Marrari,3 K. Hadi,1 C. Macedo,1 D. Metes,1 A. Shields,4 R. Alloway,5 A. Zeevi,3 F. Lakkis,1 E. Woodle,4 G. Chalasani.1,2

    1Surgery & STI(1), Medicine(2), Pathology(3), University of Pittsburgh, Pittsburgh; 2Surgery(4) & Medicine(5), University of Cincinnati College of Medicine, Cincinnati.

    Peripheral blood B cell subpopulations were assessed over time (1, 3, 6, 9, and 12 months) in living donor kidney transplant recipients undergoing thymoglobulin (n…
  • 2015 American Transplant Congress

    Increased Vascular Stiffness in Pediatric Renal Transplant Recipients Despite Normal Kidney Function, Blood Pressure, and Body Mass Index

    M. Seifert,1,2 N. Kulsum-Mecci,2 L. de las Fuentes,2 V. Davila-Roman,2 K. Hruska.2

    1Southern Illinois University, Springfield, IL; 2Washington University, St. Louis, MO.

    Background: Chronic kidney disease (CKD) imparts enormous cardiovascular (CV) risk that is only partially improved by renal transplantation. We sought to understand the determinants of…
  • 2015 American Transplant Congress

    Early Detection of HCC Mutations in Indeterminate Lesions Using Liquid Biopsies

    Y. Lin,1 K. Cavaness,2 Z. Zhang,1 S. Lin,3 K. Korenblat,1 G. Klintmalm,2 W. Chapman.1

    1Washington University, St. Louis, MO; 2Baylor University, Dallas, TX; 3Stanford University, Palo Alto, CA.

    Background Recent sequencing efforts have characterized the mutation profile of hepatocellular carcinoma (HCC); however, the relevance to clinical decision-making has been limited by the infrequency…
  • 2015 American Transplant Congress

    Expression Patterns of Neuropilin-1 On T Cells and a Potential Role in Transplantation

    E. Lee, H. Kim, G. Demirci.

    Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA.

    Introduction: Neuropilin-1 (NRP1) is a co-receptor for a variety of ligand families including VEGF, EGF and semaphorins all of which are often produced by malignant…
  • 2015 American Transplant Congress

    Alloimmune Regulation and Long-Term Allograft Survival Induced by Short-Term Administration of Chinese Medicine Cornus Officinalis and Cuscuta Sinensis Lam

    Z. Dai, Y. Zeng, X. Liu, Z. Chuan.

    Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, Guangdong, China.

    Achieving long-term allograft survival or tolerance without continuously global immunosuppression is a highly desirable goal. This study is to induce long-term allograft survival without long-term…
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