ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Assessment of Bleeding and Thrombosis in Responders and Initial Non-Responders to Aspirin After Continuous-Flow Left Ventricular Assist Device Placement

    C. Floroff, K. Rieger, T. Veasey, S. Strout, H. Meadows, M. Stroud, J. Toole, M. Brisco, J. Cook, J. Lazarchick, W. Uber.

    Medical University of South Carolina, Charleston, SC.

    Purpose: This study evaluates bleeding and thrombosis following left ventricular assist device (LVAD) placement using platelet inhibition monitoring to determine responders to standard aspirin dosing…
  • 2015 American Transplant Congress

    Outcomes of Simultaneous Pancreas and Kidney Transplantation With a High Level of Preformed Antibodies

    H. Sharma, A. El-Bakry, V. Venkat, S. Papachristos, R. Dhanda, D. Van Dellen, T. Campbell, T. Augustine, R. Pararajasingam, A. Tavakoli, B. Forgacs.

    Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.

    BACKGROUND:There is paucity of data of outcomes of simultaneous pancreas and kidney transplantation in recipients with preformed antibodies. Newer induction agents have been used with…
  • 2015 American Transplant Congress

    Which Place of Pancreas Graft Biopsy in the Management of Pancreas Transplant Recipients?

    F. Buron, M. Rabeyrin, O. Rouvière, S. Reffet, C. Chauvet, O. Thaunat, M. Brunet, R. Cahen, S. Daoud, C. Pouteil-Noble, R. Codas, L. Badet, E. Morelon.

    Hospices civils de Lyon, Lyon, France.

    Introduction.Rejection or autoimmune recurrence is often difficult to diagnose in the field of pancreas transplantation. The place of pancreas graft biopsy in the management of…
  • 2015 American Transplant Congress

    “2mm” Is Reasonable and Feasible Cutoff Value of Indication for Vascular Reconstruction in a Kidney Allograft With Multiple Arteries

    D. Iwami, K. Morita, H. Sasaki, Y. Oishi, H. Higuchi, N. Shinohara.

    Urology, Hokkaido University, Sapporo, Hokkaido, Japan.

    Introduction: Multiple renal arteries are found in 18 to 43% of donor kidneys. We've been using cutoff diameter of <2mm for accessory arteries measured by…
  • 2015 American Transplant Congress

    Eomesodermin Expression By Alloreactive Non-Human Primate CD8+ Memory T Cells: Influence of CTLA4Ig and Regulatory DC Infusion in Renal Allograft Recipients

    M. Ezzelarab,1 L. Lu,1 H. Guo,1 A. Zahorchak,1 W. Shufesky,1 D. Cooper,1 A. Morelli,1,2 A. Thomson.1,2

    1Surgery - Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; 2Immunology, University of Pittsburgh, Pittsburgh, PA.

    Background:Memory T cells (Tmem), particularly those resistant to costimulation blockade (CoSB), are considered a major barrier to transplant tolerance. The T-box transcription factor Eomesodermin (Eomes)…
  • 2015 American Transplant Congress

    Combination of Clinical and Genetic Factors for Delayed Kidney Graft Function Prediction

    A. Goncalves-Primo,1,2 E. Campos,1,2 J. Medina-Pestana,2,3 H. Tedesco-Silva,3 M. Gerbase-DeLima.1,2

    1Immunogenetics Institute, AFIP, São Paulo, SP, Brazil; 2Universidade Federal de São Paulo, São Paulo, SP, Brazil; 3Hospital do Rim e Hipertensão- FOR, São Paulo, SP, Brazil.

    In this study we sought to determine the risk for delayed graft function (DGF) in kidney transplants (Tx) with deceased donors (DD) through the analysis…
  • 2015 American Transplant Congress

    Biomarker Panel Profile for Identification of High-Risk Patients After Heart Transplantation

    M. Barten,1 M.-T. Dieterlen,2 J. Garbade,2 F. Mohr.2

    1Cardiovascular Surgery, Universisty Heart Center Hamburg, Hamburg, Germany; 2Cardiac Surgery, University Leipzig Heart Center, Leipzig, Germany.

    Background: The first year after cardiac transplantation is critical for transplant survival and long-term outcome. Identification of suitable biomarkers for detection of rejection processes is…
  • 2015 American Transplant Congress

    The Effect of Systemic Catecholamine Application On the Microcirculation in Liver Procurement

    M. Strempel,1 M. Kaths,1 H. Lang,1 G. Otto,1 V. Weyer,2 O. Kempski,3 A. Heimann,3 A. Schad,4 D. Foltys.1

    1Department of Transplantation and Hepatobiliopancreatic Surgery, University Medical Centre, Johannes Gutenberg-University, Mainz, Germany; 2Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Centre, Johannes Gutenberg-University, Mainz, Germany; 3Institute of Neurosurgical Pathophysiology, University Medical Centre, Johannes Gutenberg-University, Mainz, Germany; 4Institute of Pathology, University Medical Centre, Johannes Gutenberg-University, Mainz, Germany.

    Introduction: The most vulnerable part in liver transplantation remains the biliary system. There is evidence, that insufficient perfusion during multi-organ procurement plays a major role…
  • 2015 American Transplant Congress

    The Immunosuppressive Effect of CTLA4Ig Monotherapy Depends On the Presence of Tregs Only at Suboptimally Low Doses

    C. Schwarz,1 L. Unger,1 B. Mahr,1 K. Aumayr,2 N. Pilat,1 K. Hock,1 A. Farkas,1 I. Kristo,1 T. Wekerle.1

    1Dept. of Surgery, Medical University of Vienna, Vienna, Austria; 2Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.

    Background: CTLA4Ig/belatacept has been recently approved for immunosuppression after renal transplantation. Concerns persist, however, that a paradoxical dose-response relationship might exist for CTLA4Ig in which…
  • 2015 American Transplant Congress

    Mechanisms Underlying Treg Dysfunction in DAIH- Role for PD-L1?

    A. Arterbery,1 M. Martinez,2 S. Lobritto,2 Y. Avitzur,3 K. Raddassi,1 M. Kleinewietfeld,4 U. Ekong.1

    1Yale, NH; 2Columbia, NY; 3HSC, Toronto, Canada; 4Dresden University of Technology, Dresden, Germany.

    Background: we have previously shown that ex vivo Tregs from patients with DAIH demonstrate differentiation plasticity towards TH17. To understand the mechanisms underlying this we…
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