ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Delayed Graft Function (DGF) in Kidney Transplant Recipients (KTRs) Is Associated With Early Allograft Inflammation and Progressive Fibrosis Within 3 Months

    A. Cherukuri, R. Mehta, P. Sood, S. Chen, G. Mour, A. Tevar, P. Randhava, S. Hariharan.

    University of Pittsburgh, Pittsburgh.

    DGF had been shown to be deleterious to KTR outcomes. Analysis of histological progression in KTRs with DGF was previously not attempted. In this prospective…
  • 2015 American Transplant Congress

    Quality of Life in Elderly Kidney Transplant Recipients over 70 Years of Age

    B. Rouphael, S. Reule, A. Matas, H. Ibrahim.

    Department of Medicine, University of Minnesota, Minneapolis, MN.

    Objectives:Kidney transplantation in the elderly provides a survival advantage in comparison with those who remain on dialysis. However, the impact of transplantation on the quality…
  • 2015 American Transplant Congress

    Thymoglobulin Administration During Multi-Visceral and Isolated Small Bowel Procurement Does Not Adversely Affect the Survival of Harvested Organs

    G. Jain, T. Burnett, J. Preheim, L. Vargas, W. Grant, A. Langnas, D. Mercer, G. Jain.

    Division of Transplantation, Department of Surgery, University of Nebraska Medical Center, Omaha, NE.

    Anti-thymocyte globulin administration in donors before intestinal procurement may result in decreased graft versus-host disease (GVHD) due to reduced recipient lymphocyte trafficking after reperfusion. Reluctance…
  • 2015 American Transplant Congress

    Late Onset Cluster of Pneumocystis Jirovecii Pneumonia (PJP) in Renal Transplant Patients: Re-Examining Prophylaxis Strategies

    G. Sekhon,1 L. Gunaratnam,1 H. Iyer,1 J. Johnson,1 N. Muirhead,1 A. Newman,2 F. Rehman,1 M. Weir,1 M. Silverman,3 A. House,1 A. Jevnikar,1 S. Hosseini-Moghaddam.3

    1Division of Nephrology, Department of Medicine, London Health Sciences Centre, Western University, London, ON, Canada; 2Coordinator, Infection Prevention and Control, London Health Sciences Centre, London, ON, Canada; 3Division of Infectious Diseases, Department of Medicine, London Health Sciences Centre, Western University, London, ON, Canada.

    PJP may be associated with severe pulmonary involvement in kidney transplant recipients. We have had a long term policy of routine prophylaxis for 1 year…
  • 2015 American Transplant Congress

    Microcirculation Inflammation in Early Surveillance Renal Biopsy in Sensitized Patients Did Not Correlate With Graft Outcome

    P. Souza,1 D. Machado,1 D. David,1 G. Bezerra,1 F. Jota de Paula,1 H. Rodriges,2 W. Nahas,1 E. David Neto,1 M. Castro.1

    1Renal Transplant Unit, HC - FMUSP, S Paulo, SP, Brazil; 2Lab de HLA, InCor, S Paulo, SP, Brazil.

    Introduction: Microcirculation inflammation (MI) at 3-month renal biopsies and preformed donor-specific antibodies (DSA) are considered predictors of bad outcome in sensitized patients. Earlier biopsies and…
  • 2015 American Transplant Congress

    DQB1 Epitope Matching Predicts the Development of De Novo DSA and Antibody Mediated Rejection

    M. Willicombe,1 M. Blow,2 P. Brookes,2 E. Santos,2 D. Taube.1

    1Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom; 2H&I, Hammersmith Hospital, London, United Kingdom.

    HLA DQ antibodies are the commonest de novo [DN] DSA specificity seen post renal transplantation. Their presence is associated with antibody mediated injury and allograft…
  • 2015 American Transplant Congress

    Eculizumab in the Treatment of Early Severe Acute Antibody Mediated Rejection Following HLA-Compatible Kidney Transplantation-Case Series

    M. Singh,1 N. Macias,2 V. Tatapudi,1 B. Lee.1

    1Transplant Nephrology, UCSF Medical Center, San Francisco, CA; 2Nephrology, Hospital Gregorio Maranon, Madrid, Spain.

    Severe early acute antibody-mediated rejection (AMR) is associated with poor allograft outcomes. Eculizumab is a humanized mouse monoclonal antibody against complement factor C5 that has…
  • 2015 American Transplant Congress

    Alemtuzumab Dose Adjusted for Weight Reduces Infection Post-Renal Transplantation

    C.-H. Yoon, M. Willicombe, C. Jogia, R. Charif, J. Galliford, A. McLean, D. Taube.

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Alemtuzumab [AL] has been increasingly used as an induction agent in renal transplantation. It causes potent lymphocyte depletion and as has been shown to reduce…
  • 2015 American Transplant Congress

    Single Center Experience With the Use of an Abbreviated Anti-Thymocyte Globulin and Basiliximab Combination Protocol in Renal Transplantation

    V. Whittaker,1 D. Halleran,1 S. Narsipar,1 J. Melancon.2

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Surgery, George Washington University, Washington, DC.

    Purpose: To report one year outcomes from single center experience with a novel induction regimen using anti-thymocyte globulin ( ATG)(rabbit)rATG (3 mg/kg) in divided doses…
  • 2015 American Transplant Congress

    Largest Single Center Experience of Pre-Transplant Outcomes After Bariatric Surgery in Ethnic Minorities With Chronic Kidney Disease

    I. Thomas,2 J. Gaynor,1 T. Joseph,1 N. De La Cruz,1 D. Roth,2 A. Mattiazzi,2 W. Kupin,2 L. Chen,1 G. Burke,1 M. Goldstein,1 G. Ciancio,1 G. Guerra.2

    1Surgery, University of Miami/Jackson Memorial Hospital, Miami, FL; 2Medicine, University of Miami/Jackson Memorial Hospital Miami Transplant Institute, Miami, FL, United Kingdom.

    Background:Ethnic minorities have disproportionately lower renal transplant rates. The increased prevalence of obesity seen in ethnic minorities further places them at a disadvantage due to…
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