2015 American Transplant Congress
Preemptive Therapy for Cytomegalovirus Disease in Liver Transplant Recipients-A Single Center Experience
1Rush University Medical Center, Chicago, IL; 2Lahey Hospital and Medical Center, Boston, MA.
Background: Cytomegalovirus (CMV) is a common opportunistic infection after liver transplantation and is associated with significant morbidity and mortality. There are two strategies for preventing…2015 American Transplant Congress
Chest Wall,Thymus, and Heart Transplant: Pushing the Boundary of Solid Organ Allotransplantation
Objective:The last 10 years have ushered in the clinical reality of upper extremity and face transplantation with animal models and basic science evidence to support…2015 American Transplant Congress
Remote Ischemic Preconditioning Increases Transplantation of Abdominal Organs in Standard Criteria Neurological Death Donors
Background: Remote ischemic preconditioning (RIPC) induces innate protective mechanisms in remote organs. We hypothesized RIPC soon after neurological death (ND) would improve donor organ function…2015 American Transplant Congress
Is Electron Microscopy Adding a Diagnostic Advantage in the Evaluation of Renal Allograft Biopsies for Antibody Mediated Rejection (AMR)?
Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.
Some electron microscopy (EM) findings have been consistently associated with antibody mediated microvascular injury; however, no large studies have been performed examining the concrete advantage…2015 American Transplant Congress
Domino Liver Transplant from Donors With MSUD: Operative Strategy and Long-Term Outcomes
Liver transplant (txp) is the definitive branched chain keto-acid (BCKA) replacement therapy for patients with Maple Syrup Urine Disease (MSUD). Due to the extra-hepatic distribution…2015 American Transplant Congress
UNOS KDPI Score Is Significantly Overestimated for Pediatric En-Bloc Kidneys
Transplant Center, University of California, Davis, Sacramento, CA.
When Rao, et al, published the Kidney Donor Risk Index model (KDRI) (Transplantation 2009;88:231-236), they found coefficients for HLA match, cold ischemic time, en-bloc (EB)…2015 American Transplant Congress
Marked Suppression of Posttransplant Alloantibody Production and Primed B cell Function In Vivo by mTOR Inhibition Compared to Calcineurin Inhibition
Department of Surgery, CTC, The Ohio State University, Columbus, OH.
mTOR inhibitors [mTORi; Rapamycin, (Rapa)] and calcineurin inhibitors [CNi; Tacrolimus (Tac)] are immunosuppressives commonly used to suppress rejection of transplants. Despite widespread use following transplantation…2015 American Transplant Congress
Trajectory of Measured GFR Decades After Kidney Donation: Hyperfiltration Never Seems to End!
While the effect of uninephrectomy on loss of GFR is a cardinal issue for potential kidney donors, current information relies on surrogates of unknown validity,…2015 American Transplant Congress
Alloantibody-Dependent Macrophage-Mediated Hepatocellular Damage Is Dependent on FcγRI, FcγRIII, and Reactive Oxygen Species
Dept of Surgery, CTC, The Ohio State University Wexner Medical Center, Columbus, OH.
Alloantibodies (alloAb) play a critical role in rejection after transplantation. Despite this, the cellular mechanisms contributing to alloAb-mediated allograft damage are not well understood. Using…2015 American Transplant Congress
Longitudinal Follow-Up of Cardiovascular Comorbidity in Pediatric Renal Transplant Recipients – Results from the 4C-T Study
Purpose: Children with chronic kidney disease (CKD) carry an increased cardiovascular risk. Cardiovascular death is the second leading cause of death in children after renal…
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