Am J Transplant, Volume 5, Suppl 3 Archives - Page 86 of 170 - ATC Abstracts

2015 American Transplant Congress
Increased Frequency of Terminally Differentiated and Exhausted CD8+ T Cells Is Associated With Adverse Clinical Outcome After Mechanical Circulatory Support Device Implantation
J. Schaenman,¹ Y. Korin,² T. Sidwell,² G. Sunga,² G. Bondar,³ N. Wisniewski,³ M. Kwon,⁴ M. Cadeiras,³ M. Deng,³ E. Reed.²
¹Medicine/Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA; ²Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA; ³Medicine/Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA; ⁴Cardiothoracic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Clinical outcomes vary after mechanical circulatory support device (MCSD) implantation, with some patients developing multi organ system dysfunction (MOD), sometimes leading to death. We hypothesized…
2015 American Transplant Congress
Long-term Patient and Graft Survival After Kidney Transplantation in Recipients With Hepatitis C Virus Infection
N.-Y. Heo, P. Udompap, A. Mannalithara, W. Kim.
Division of Gastroenterology and Hepatology, Stanford University, Stanford.
Background: The prevalence of hepatitis C virus (HCV) infection among kidney transplant (KTx) recipients is higher than that in the general population. With the advent…
2015 American Transplant Congress
Is BMI of 28 an Appropriate Cutoff for Simultaneous Pancreas Kidney Transplant in Type II Diabetes?
E. Ahmed, D. Bruce, I. Carmody, A. Cohen, G. Loss, T. Reichman, J. Seal, H. Bohorquez.
Multi-Organ Transplant Institute, Ochsner Clinic Foundation, New Orleans, LA.
In simultaneous pancreas and kidney (SPK) transplantation, obesity has been reported to be associated with inferior survival and increased post-transplant complications. With implementation of the…
2015 American Transplant Congress
Variables Related to the Development of Donor Specific Antibodies (DSA) Post-Kidney Transplant (KTx): Implications for Late Graft Histology and Survival
F. Cosio,¹ C. Schinstock,¹ M. Stegall.²
¹Medicine, Mayo Clinic, Rochester, MN; ²Surgery, Mayo Clinic, Rochester, MN.
Introduction. The incidence of de novo DSA increases post-KTx. DSA is associated to reduced graft survival likely due to chronic antibody mediated rejection (cAMR). However,…
2015 American Transplant Congress
National Outcomes of Kidney Tranplantation from Diabetic Donors: A Mate-Kidney Analysis
J. Cohen,¹ P. Reese,¹ P. Porrett,² R. Bloom,¹ K. Forde,³ D. Sawinski.¹
¹Renal Division, Univ. of Penn, Philadelphia, PA; ²Dept of Surgery, Univ. of Penn, Philadelphia, PA; ³Division of Gastroenterology, Univ. of Penn, Philadelphia, PA.
Utilization of diabetic donor kidneys has increased, though scarce patient and allograft survival data are available for recipients of these organs. Using United Network for…
2015 American Transplant Congress
Estimation of Glomerular Filtration Rate With Serum Cystatin C Accurately Discriminates Renal Dysfunction in Liver Transplant Candidates With End-Stage Liver Disease
S. Gonzalez,¹ J. Trotter,¹ H. Szerlip,² M. Levy,³ A. Chandrakantan,⁴ A. Yango,⁴ A. Rajagopal,⁴ Y. Barri,⁴ K. Rice,⁴ M. Saim,² L. Melton,⁴ M. Emmett,² G. Klintmalm,³ B. Fischbach.⁴
¹Hepatology, Baylor Simmons Transplant Institute, Fort Worth, TX; ²Nephrology, Baylor University Medical Center, Dallas, TX; ³Transplant Surgery, Baylor Simmons Transplant Institute, Fort Worth, TX; ⁴Nephrology, Baylor Simmons Transplant Institute, Fort Worth, TX.
Background: Renal insufficiency is common in end-stage liver disease (ESLD) and is linked to survival in patients awaiting liver transplantation. Serum creatinine correlates poorly with…
2015 American Transplant Congress
Desensitization With Costimulation Blockade and Proteasome Inhibition in a Non-Human Primate Model of Kidney Transplantation
C. Burghuber,^1,2 J. Kwun,¹ E. Page,¹ A. Gibby,¹ F. Leopardi,³ A. Farris,¹ N. Iwakoshi,¹ S. Knechtle.^1,3
¹Emory Translant Center, Emory University, Atlanta, GA; ²Medical University Vienna, Vienna, Austria; ³Duke University, Durham, NC.
[Background] Sensitization is a growing problem on the kidney waiting list. Alloantibody can significantly deteriorate graft survival. Currently used desensitization strategies are time-consuming, expensive and…
2015 American Transplant Congress
Part II: Rates and Determinants of Progression for De Novo Donor-Specific Antibody Mediated Kidney Allograft Injury
C. Wiebe,^1,2 I. Gibson,³ D. Pochinco,² P. Birk,⁴ T. Blydt-Hansen,⁴ J. Ho,^1,5 M. Karpinski,¹ A. Goldberg,⁴ L. Storsley,¹ D. Rush,¹ P. Nickerson.^1,2,5
¹Medicine, University of Manitoba, Winnipeg, MB, Canada; ²Immunogenetics, Diagnostic Services of Manitoba, Winnipeg, MB, Canada; ³Pathology, University of Manitoba, Winnipeg, MB, Canada; ⁴Pediatric and Child Health, University of Manitoba, Winnipeg, MB, Canada; ⁵Immunology, University of Manitoba, Winnipeg, MB, Canada.
The development of de novo donor-specific antibody (dnDSA) is an independent predictor of allograft loss in renal transplantation. Rates and determinants of clinical pathologic progression…
2015 American Transplant Congress
Muscle Mass Measurement Is Objective and More Predictive of Expected Mortality Than Functional Status in High MELD Liver Transplant Recipients
J. Nolte,¹ S. Gordon Burroughs,¹ D. Victor,¹ C. Mobley,¹ N. Yu,² T. Hirase,¹ A. Saharia,¹ A. Rajaraman,¹ L. Moore,¹ A. Gaber,¹ R. Ghobrial.¹
¹Surgery, Houston Methodist Hospital, Houston, TX; ²Radiology, Houston Methodist Hospital, Houston, TX.
Introduction: Calculations used to determine expected survival post-liver transplant (OLT) are in part based on pre-OLT functional status. Functional status is subjectively measured by Karnofsky…
2015 American Transplant Congress
Is Pretransplant Anti-A/B Antibody Removal Prerequisite for Successful ABO Incompatible Kidney Transplantation in Children?
S. Shishido,¹ T. Kawamura,¹ Y. Hamasaki,² Y. Takahashi,¹ Y. Hyodo,¹ Y. Itabashi,¹ H. Nihei,¹ T. Yonekura,¹ Y. Inaba,² Y. Yoshida,² K. Sakai,¹ A. Aikawa.¹
¹Nephrology, Toho University, School of Medicine, Tokyo, Japan; ²Pediatric Nephrology, Too University, School of Medicine, Tokyo, Japan.
Purpose: We have recently demonstrated that the long-term outcome of ABO incompatible living donor kidney transplantation (ABOiKT) in children was comparable to those of ABO…