Am J Transplant, Volume 5, Suppl 3 Archives - Page 81 of 170 - ATC Abstracts

2015 American Transplant Congress
Comparison of Pharmacokinetics and Pharmacogenomics of Once-Daily Extended-Release MeltDose® Tacrolimus Tablets (Envarsus® XR) Vs. Twice-Daily Tacrolimus Capsules in Stable African American Kidney Transplant Patients: A Randomized Cross-Over Study
J. Trofe-Clark,^1,2 D. Brennan,³ P. West-Thielke,⁴ M. Milone,⁵ M. Lim,² R. Bloom.²
¹Pharmacy Services, Hospital of the University of Pennsylvania, Philadelphia; ²Renal Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia; ³Renal Division, Washington University, St. Louis; ⁴University of Illinois at Chicago, Chicago; ⁵Penn Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
The CYP3A5 genotype is the most significant genetic factor impacting tacrolimus (tac) metabolism; expresser's of this genotype require higher tac doses to achieve therapeutic tac…
2015 American Transplant Congress
Establishment of a Novel Model for Hypothermic Machine Perfusion In Vivo in Rabbits
Z. Zhong,¹ Z. Liu,¹ R. Wang,¹ Z. Fu,² Y. Zhang,² Q. Hu,¹ K. Jin,¹ D. Ko,³ Y. Wang,¹ Q. Ye.^1,2
¹Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei, China; ²The 3rd Xiangya Hospital of Central South University, Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha, Hunan, China; ³Massachusetts General Hospital, Department of Urology, Boston, MA.
Background: Hypothermic machine perfusion (MP) could improve outcome after transplantation of DCD kidneys, but protective mechanisms of MP remain largely unknown. Therefore, this study aims…
2015 American Transplant Congress
Post-Kidney Allograft Nephrectomy Anti-HLA Immunization Is Not Due to a Release of Anti-HLA Antibodies from the Failed Kidney
D. Milongo,^1,3 N. Congy-Jolivet,^2,3,4 A. Del Bello,^1,3 F. Sallusto,⁵ C. Guilbeau-Frugier,⁶ L. Rostaing,^1,3 N. Kamar.^1,3
¹Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France; ²Laboratoire d'Immunologie, CHU de Toulouse, Toulouse, France; ³Université Toulouse III Paul-Sabatier, Toulouse, France; ⁴Laboratoire d'Immunogénétique Moléculaire, EA 3034, Université Toulouse III Paul-Sabatier, Toulouse, France; ⁵Department of Urology, CHU Rangueil, Toulouse, France; ⁶Department of Histopathology, CHU Rangueil, Toulouse, France.
Background and aims: The reasons for the increased incidence of de novo anti-HLA donor specific antibodies (DSAs) that is observed after kidney allograft nephrectomy (NTx)…
2015 American Transplant Congress
Can the Need for Graft Nephrectomy After Late Renal Transplant Failure Be Predicted?
K. Bunthof, C. Verhoeks, L. Hilbrands.
Nephrology, Radboud University Medical Centre, Nijmegen, Netherlands.
Introduction: Graft nephrectomy is universally recommended when graft survival is less than 6 months. In case of later graft failure it is not always necessary…
2015 American Transplant Congress
Intraoperative Renal Replacement Therapy During Liver and Liver-Kidney Transplant: Outcomes of 155 Cases
M. Mai,¹ E. Golan,² K. Croome,¹ A. Keaveny,¹ B. Taner,¹ T. Gonwa,¹ H. Wadei.¹
¹Transplantation, Mayo Clinic, Jacksonville, FL; ²Florida State University, Tallahassee, FL.
Background: Renal dysfunction in liver (LT) and liver-kidney (LKT) transplant candidates increases intraoperative risks of electrolyte disturbances and volume excess complications. The role of intraoperative…
2015 American Transplant Congress
Technical Aspects of Reconstruction of Middle Hepatic Vein and Multiple Inferior Right Hepatic Veins Using Dual Artificial Vascular Grafts in Right Lobe Living Donor Liver Transplantation: “V-Plasty” Technique for Common Outflow Reconstruction Vs Second IVC Anastomosis
P.-C. Li, L. Jeng, A. Thorat, H.-R. Yang, C.-C. Yeh, T.-H. Chen, S.-C. Hsu.
Organ Transplantation Center, China Medical University Hospital, Taichung, Taiwan.
Background:Presence of multiple inferior right hepatic veins (IRHV) along with undrained median sector pose technical difficulties in right lobe living donor liver transplantation (LDLT). Several…
2015 American Transplant Congress
Kidney Paired Donation: National Activity and Perspectives
T. Dunn,¹ S. Fayek,² C. Marsh,³ P. Abt.⁴
¹Surgery, University of Minnesota, Minneapolis, MN; ²Surgery, Rush University Medical Center, Chicago, IL; ³Surgery, Scripps Health, La Jolla, CA; ⁴Surgery, University of Pennsylvania, Philadelphia, PA.
While utilization of Kidney Paired Donation (KPD) continues to increase, the potential is not fully realized. We surveyed kidney transplant (KTX) professionals to evaluate perceptions…
2015 American Transplant Congress
Renal Mass as a Determinant Factor of Long-Term Post-Donation Anemia
S. Shah,¹ B. Lankowsky,² Z. Zaky,¹ S. Nurko,¹ R. Fatica,¹ S. Gebreselassie,¹ B. Stephany,¹ E. Poggio.¹
¹Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH; ²Case Western Reserve University, SOM, Cleveland, OH.
Living kidney donors lose approximately 50% of renal mass when donating a kidney however, renal function recovers to within 60-70% of baseline within weeks to…
2015 American Transplant Congress
Lung Transplant Patients With Elevated Baseline Pulmonary Arterial Pressures Are More Likely to Recover from Post-Transplant Acute Kidney Injury
B. Stephany,¹ E. Wehbe,² M. Budev.³
¹Nephrology & Hypertension, Cleveland Clinic, Cleveland, OH; ²Nephrology, Wichita, KS; ³Pulmonary, Allergy & Critical Care, Cleveland Clinic, Cleveland, OH.
Purpose: Elevated pre-operative pulmonary arterial pressures predict acute kidney injury (AKI) after lung transplant. It is unknown if the elevated pulmonary pressures predict recovery from…
2015 American Transplant Congress
The Impact of Donor and Recipient Weight Incompatibility on Outcomes in Renal Transplantation
L. Wong,¹ S. Moran,¹ A. Counihan,² P. Cunningham,² P. O'Kelly,¹ P. Conlon.¹
¹Nephrology, Beaumont Hospital, Dublin, Ireland; ²Urology and Transplantation, Beaumont Hospital, Dublin, Ireland.
Background: Kidney transplantation has been proposed as an accelerated model of nephron reduction resulting from the accumulation of repeated insults, both immunologic and non-immunologic events.…