ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Delivery of Heme Oxygenase-1-Cell Penetrating Peptide (HO-1-CPP) Into Hepatocytes, Kupffer and Islet Cells in In Vitro and Ex Vivo Models of Cold Ischemia

    A. Venkatachalam,1 C. Wood,1 Q. Hu,1 I. Alwayn.2

    1Surgery, Dalhousie University, Halifax, NS, Canada; 2Surgery, Pathology, Microbiology & Immunology, Surgical Lead Multi Organ Transplant Program, QEII Health Sciences Center, Dalhousie University, Halifax, NS, Canada.

    In an attempt to increase the number of donor organs available to transplantation extended criteria donor (ECD) organs are more frequently considered. Unfortunately, ECD organs…
  • 2015 American Transplant Congress

    Remote Ischemic Perconditioning Induces Protection Against Hepatic Ischemia/Reperfusion Injury in Rats Via Downregualtion of Bax and Cleaved Caspase-3 Expression

    H. Ahn, M. Park, S. Joo, B. Kim.

    Department of Surgery, Kyung Hee University, Seoul, Korea.

    Purpose: The aim of this study was to determine whether remote ischemic preconditioning (rPeC) method can protect the hepatic IR injury in rat or not…
  • 2015 American Transplant Congress

    Mitochondrial Feedback Mechanisms in Kidney Cell Senescence

    K. De Vusser,1 K. Hochstenbach,2 E. Winckelmans,2 E. Lerut,3 D. Kuypers,1 T. Nawrot,2 M. Naesens.1

    1Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium; 2Centre for Environmental Sciences, Hasselt University, Hasselt, Belgium; 3Department of Pathology, University Hospitals Leuven, Leuven, Belgium.

    BackgroundProgressive DNA damage (telomere attrition) is considered one of the key instigators of ageing. Different models for ageing where DNA damage leads to accelerated senescence…
  • 2015 American Transplant Congress

    Long-Term Outcomes and Recurrence Risk of Four Common Primary Glomerular Diseases Following Transplantation

    L. Maursetter, S. Panzer, S. Waheed, M. Mohamed, S. Parajuli, G. Leverson, B. Astor, D. Mandelbrot, A. Djamali.

    Division of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.

    In the largest single center study of its kind, we assessed patient and allograft outcomes in 598 patients with the four most common causes of…
  • 2015 American Transplant Congress

    Molecular Classifiers Accurately Measure the Degree of Fibrosis in Human Kidney Transplant Biopsies

    J. Venner, J. Reeve, P. Halloran.

    University of Alberta, Edmonton, Canada.

    Irreversible injury in organ transplants is an important clinical parameter, and is estimated by histology as the observed “ci” lesion, but with considerable inter-observer variability…
  • 2015 American Transplant Congress

    Comparison of Renal Outcomes for Liver Transplant Recipients With Pretransplant Renal Dysfunction Receiving Sirolimus Or Tacrolimus With Rabbit Antithymocyte Globulin Induction

    B. Duhart,1 W. Ally,2 V. Rao,3 A. Krauss,4 J. Eason,3 J. Vanatta.3

    1University of Tennessee College of Pharmacy, Memphis, TN; 2Pharmacy, University of Virginia Medical Center, Charlottesville, VA; 3Surgery, Methodist University Hospital Transplant Institute/University of Tennessee Health Science Center, Memphis, TN; 4Pharmacy, Methodist University Hospital, Memphis, TN.

    Published data are limited describing renal outcomes in orthotopic liver transplant (OLT) recipients prescribed de novo sirolimus (SRL) maintenance immunosuppression and rabbit antithymocyte globulin (rATG).…
  • 2015 American Transplant Congress

    Fast Track of Adult-to-Adult Live Donor Liver Transplant Recipients: Avoiding ICU Admission Reduces Complications and Post Transplant Hospital Stay

    J. Echeverri, N. Goldaracena, A. Singh, G. Sapisochin, N. Selzner, M. Cattral, P. Greig, L. Lilly, I. McGilvray, G. Levy, A. Ghanekar, E. Renner, D. Grant, S. McCluskey, M. Selzner.

    Toronto General Hospital, Toronto, ON, Canada.

    Objective: We investigated if fast track of adult-to-adult live donor liver transplant (LDLT) recipients is safe and provides benefits for the post transplant hospital stay.Methods:…
  • 2015 American Transplant Congress

    Outcomes After Right Kidney Living Donor Transplant Are Associated With Center Volume

    R. Reed, P. MacLennan, B. Shelton, D. Sonnier, M. Hanaway, J. Goodman, C. Young, M. Deierhoi, J. Locke.

    Surgery/Transplantation, University of Alabama at Birmingham, Birmingham, AL.

    Background: Right kidney living donor transplant (RKLDT) is a high-risk, low-volume procedure that is associated with increased risk for early graft failure. It is unclear…
  • 2015 American Transplant Congress

    Are Living Kidney Donors Who Apply Via a Web-Based Screening Application as Likely to Be Evaluated and Donate as Compared to Phone Applicants?

    H. Schaefer, M. Tanaka, I. Feurer, A. Dreher, P. Newbern, D. Moore.

    Vanderbilt University, Nashville.

    Purpose: Most transplant centers screen self-referring donors using phone and written surveys. Previous research at our center has shown that a web-based application for screening…
  • 2015 American Transplant Congress

    High Atherosclerotic Burden in Pediatric Lung Transplant Recipients

    A. Melk,1 D. Thurn-Valsassina,1 N. Schwerk,2 F. Brinkmann,2 C. Mueller.2

    1Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany; 2Department of Pediatric Pneumology and Neonatology, Hannover Medical School, Hannover, Germany.

    Purpose: Pediatric lung transplant patients have been reported to have an increased incidence of hypertension. This incidence might be caused by the treatment with calcineurin…
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