Am J Transplant, Volume 5, Suppl 3 Archives - Page 77 of 170 - ATC Abstracts

2015 American Transplant Congress
Normothemic Machine Perfusion of Liver Grafts Promotes Liver Regeneration and Inhibits Tissue Inflammation
E. Xystrakis, J. Lozano, R. Danger, M. Martinez-Llordella, P. Srinivasan, N. Heaton, C. Coussios, A. Sanchez-Fueyo, Y. Ma, W. Jassem.
Institute of Liver Studies, King's College London School of Medicine at King's College Hospital, London, United Kingdom; Plataforma de Bioinformatica, Centro de Investigación Biomédica en red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clinic, Centre Esther Koplovitz (CEK), Barcelona, Spain; Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom.
Background & aim: liver transplantation I/R injury is associated with inflammation, affecting graft outcome. Ex-vivo normothermic machine perfusion (NMP) to donor livers before transplantation reduces…
2015 American Transplant Congress
CXCR4-SDF1α Blockade Reduces the Severity of Murine Heart Allograft Rejection
X. Wang,¹ J. Fu,¹ B. Wilde,¹ L. Jing,¹ J. Zhu,¹ A. Kribben,¹ O. Witzke,¹ A. Hoerning.^2,3
¹Department of Nephrology, University Hospital Essen, University Duisburg-Essen, Essen, Germany; ²Department of Pediatrics II, University Hospital Essen, University Duisburg-Essen, Essen, Germany; ³Department of Pediatric and Adolescent Medicine, University Hospital Erlangen, Friedrich-Alexander University Erlangen, Erlangen, Germany.
Introduction: The interaction of the CXCR4/SDF1α axis plays a critical role in the retention of hematopoietic stem cells in bone marrow. We hypothesized that the…
2015 American Transplant Congress
Safety and Efficacy of 3-Month Ciprofloxacin for BK Prophylaxis in Kidney Transplantation
S. Patel, R. Knight, J. Loucks, S. Kuten, A. Gaber.
Houston Methodist Hospital, Houston, TX.
Flouroquinolones(FQ) have been shown to inhibit BK virus (BKV) in vitro, however clinical data remains mixed. We reviewed a pilot protocol of BK prophylaxis with…
2015 American Transplant Congress
Delayed Graft Function (DGF) in Kidney Transplant Recipients (KTRs) Is Associated With Early Allograft Inflammation and Progressive Fibrosis Within 3 Months
A. Cherukuri, R. Mehta, P. Sood, S. Chen, G. Mour, A. Tevar, P. Randhava, S. Hariharan.
University of Pittsburgh, Pittsburgh.
DGF had been shown to be deleterious to KTR outcomes. Analysis of histological progression in KTRs with DGF was previously not attempted. In this prospective…
2015 American Transplant Congress
Quality of Life in Elderly Kidney Transplant Recipients over 70 Years of Age
B. Rouphael, S. Reule, A. Matas, H. Ibrahim.
Department of Medicine, University of Minnesota, Minneapolis, MN.
Objectives:Kidney transplantation in the elderly provides a survival advantage in comparison with those who remain on dialysis. However, the impact of transplantation on the quality…
2015 American Transplant Congress
Relationship of Donor Age and Distance in Deceased Donor Lung Offers in the US
L. Edwards,¹ L. Robbins Callahan,¹ W. Cherikh,¹ J. Rogers,² K. Chan.³
¹UNOS, Richmond, VA; ²Duke Univ, Durham, NC; ³U of Mich, Ann Arbor, MI.
Background: Lung (LU) utilization from deceased donors (DD) is considerably lower than for kidney, liver and heart. A better understanding of placement efforts may provide…
2015 American Transplant Congress
Characteristics of HIV Infected Patients Waitlisted for Kidney Transplantation
N. Law,¹ A. Doyle,¹ A. Sharma,¹ G. Malat,² T. Bias,¹ K. Ranganna,¹ D. Lee.¹
¹Department of Medicine, Drexel University, College of Medicine, Philadelphia, PA; ²Department of Surgery, Drexel University, College of Medicine, Philadelphia, PA.
IntroductionKidney transplantation in HIV+ individuals has been associated with patient and graft survival rates that are comparable to those reported for HIV- populations. Despite this…
2015 American Transplant Congress
Protocol Donor Specific Antibody Monitoring After Kidney Transplantation: What Is the Utility?
C. Staino, N. Pilch, O. Moussa, K. Boyle, J. Casale, K. Covert, J. Fleming, D. Taber, H. Meadows, C. Mardis, K. Chavin, S. Nadig, J. McGillicuddy, C. Bratton, T. Srinivas, P. Baliga.
MUSC, Charleston, SC.
De novo DSA has been shown to be a negative predictor of graft outcomes. However, the utility of routine DSA monitoring in the overall kidney…
2015 American Transplant Congress
Does the C1q Assay Predict the Result of Lymphocyte Flow Cross-Match (FCxM) in Potential Renal Transplant Recipients With HLA-DSA and AHG-CDC CxM negative?
J. Arreola-Guerra, A. de Santiago, A. Arvizu, N. Gonzalez-Tableros, M. Lopez, M. Vilatoba, L. Morales-Buenrostro, J. Alberu, N. Castelan.
1Transplantation, 1aNephrology-Mineral Metabolism, Inst Nal de Ciencias Medicas y Nutricion SZ, Mexico City, Mexico.
Background. The presence of pre-transplant HLA donor specific antibodies (DSA) is a recognized risk factor for acute rejection. However, due to the test's (LUMINEX) high…
2015 American Transplant Congress
DSA Detected by ELISA-PRA Is Associated With High Risk for Development of AMR in Stable Kidney Transplant Recipients
D. Lee,¹ J. Kim,² B. Kim,³ M. Chun,⁴ I. Kim.⁵
¹Medicine, Division of Nephrology, Maryknoll General Hospital, Busan, Republic of Korea; ²Surgery, Maryknoll General Hospital, Busan, Republic of Korea; ³Laboratory Medicine, Maryknoll General Hospital, Busan, Republic of Korea; ⁴Pathology, Maryknoll General Hospital, Busan, Republic of Korea; ⁵Urology, Maryknoll General Hospital, Busan, Republic of Korea.
Background: Donor specific anti-HLA antibodies (DSA) are a major cause of antibody mediated rejection (AMR) and allograft loss, determining how to monitor patients for DSA…