2015 American Transplant Congress
Allograft Pancreatectomy: Indications and Outcomes
Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN.
Background: Indications for allograft pancreatectomy have not been clearly established, but cause and timing of graft loss, clinical symptoms and candidacy for pancreas retransplantation are…2015 American Transplant Congress
Patient Self-Reported Adherence to and Perceptions Towards Immunosuppressive Medications at the Outpatient Renal Transplant Clinic at St. Joseph's Healthcare Hamilton (SJHH)
Objectives To gain insight into the immunosuppressant adherence of patients followed by the Outpatient Renal Transplant Clinic at St. Joseph's Healthcare Hamilton (SJHH) and to…2015 American Transplant Congress
Dietary-Associated Trimethylamine N-Oxide (TMAO) Levels Is associated With Coronary Allograft Vasculopathy Following Heart Transplantation
Background: Coronary allograft vasculopathy (CAV) is a leading cause of cardiac graft failure after 1 year post transplant. It is characterized by an inflammatory vascular…2015 American Transplant Congress
Chimeric Patients Who Undergo Combined Facilitating Cell-Enriched/HSC/Renal Transplant Exhibit Robust TCR Repertoire
Combined donor kidney plus facilitating cell enriched hematopoietic stem cell (FCRx) transplants (Tx), after low intensity conditioning with fludarabine, 200-cGy total body irradiation and cyclophosphamide…2015 American Transplant Congress
Molecular and Functional Immune Assays as Non-Invasive Diagnostic Tools to Assess the Risk of Acute Subclinical Rejection After Kidney Transplantation
Subclinical allograft rejection (sc-AR) is still a main cause of allograft loss that can only be assessed through invasive surveillance biopsies. We sought to investigate…2015 American Transplant Congress
Ischemia Reperfusion Injury in Orthotopic Liver Transplantation Primes the Adaptive Immune Response and Generation of Proinflammatory Cytokines
Background: Transplanted organs are exquisitely susceptible to effects of ischemia/reperfusion injury (IRI), an immune-mediated process that occurs during transplantation and beyond. Recipient and graft outcomes,…2015 American Transplant Congress
Rapid Effector Function of TEMRA CD8 T Cells in Healthy Volunteers and in Immune-Stimulated Patients Requires Sustained Glycolytic Switch
Background. Contradictory observations have been published regarding the functionality of TEMRA CD8 T cells. TEMRA CD8 have been shown to accumulate with age or chronic…2015 American Transplant Congress
Liver-Specific Transcription Factor ATF5 Participates in Regulation of IFN-γ/B7-H1 Signaling Pathway in Liver Mesenchymal Cells
Liver transplant tolerance was initially discovered in pigs, rats and mice. A recent paper reviewed ∼400 liver transplant patients worldwide who had undergone weaning of…2015 American Transplant Congress
Serum Phosphorus Level Has Bidirectional Association With Graft Failure and Mortality in Kidney Transplant Recipients
Hyperphosphatemia in kidney transplant recipients (KTRs) is known to predict a graft and patient survival in several studies. However, studies concerned with hypophosphatemia are scarce.…2015 American Transplant Congress
Does HLA-Incompatible Transplantation Confer a Survival Advantage in the UK?
Introduction: HLA-incompatible transplantation is perceived as being a 'high-risk' option with increased mortality and morbidity for transplantation of sensitized recipients of renal transplants. Data from…
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