2015 American Transplant Congress
Donor Age and Late Rejection Are Associated With the Development of Graft Coronary Artery Vasculopathy in Pediatric Heart Transplant Recipients
Division of Pediatric Cardiology, Columbia University Medical Center, New York, NY.
Purpose: Graft coronary artery vasculopathy (GCV) is one of the major causes of morbidity and mortality in pediatric heart transplant (HT) recipients, and in fact…2015 American Transplant Congress
Association of IP-10 With Poor Islet Graft Function After Total Pancreatectomy With Islet Autotransplantation
Introduction: Total pancreatectomy with islet autotransplantation (TPIAT) is an effective treatment for refractory chronic pancreatitis. The mechanisms underlying islet graft loss, however, remain unclear. Interferon…2015 American Transplant Congress
Longterm Outcome in Pancreas Grafts After Polyomavirus Infection in Combined Kidney-Pancreas Transplants: A Single Center Report
Purpose: We retrospectively analyzed the longterm survival and function in pancreas grafts after reduction of immunosuppression due to polyomavirus infection in simultaneous pancreas kidney transplants…2015 American Transplant Congress
Ligation of the Native Ureter for Treatment of Urinary Fistula in Kidney Transplantation: Is It Safe?
Division of Urology, Renal Transplantation Unit, University of Sao Paulo, Sao Paulo, Brazil.
Purpose: Urinary fistula and ureteral stenosis occur respectively in 2-5% and 2-7.5% after kidney transplantation. Within the different causes of stenosis and fistula after kidney…2015 American Transplant Congress
Systemic and Local NK and Regulatory Cell Phenotypes and mTori-Induced Tumor-Specific Effector T-Cell Responses Are Key Players Favoring the Development of Squamous Cell Skin Carcinoma Among Kidney Transplant Patients
Renal transplant patients are at higher risk of developing squamous cell carcinoma (SCC). Immunosuppressive agents promote an imbalance between effector and regulatory tumor-specific immune responses,…2015 American Transplant Congress
Does Switching Predict Conversion: IgM De Novo Donor Specific HLA Antibodies Class Switch to IgG in Subclinical Antibody Mediated Rejection in Heart Transplant Recipients
1Cleveland Clinic, Cleveland; 2School of Medicine, Leipzig University, Leipzig, Germany.
Background: Concomitant C4d and C3d detection in heart biopsies correlates with circulating DSA and graft dysfunction. Detection of C4d only in surveillance biopsies is not…2015 American Transplant Congress
Evaluation of Natural Killer Cell Activation by NK Cell-Specific Interferon-Gamma-Releasing Assay
Introduction: Although NK cell activity (NKA) has a variety of measuring markers including chromiun release assay and flowcytometry-based cytolysis, limitations such as radioactivity and lack…2015 American Transplant Congress
Fibrosis, Not Quantitative NGAL-Staining, in Day-10 Protocol Biopsies Predicts Prolonged Duration of Functional Delayed Graft Function in a Cohort of DCD Kidney Transplant Recipients
1Nephrology, LUMC, Leiden, Netherlands; 2Pathology, LUMC, Leiden, Netherlands.
Introduction: Extended criteria deceased kidneys are associated with prolonged delayed graft function and worse patient survival. Therefore it is important to identify factors in marginal…2015 American Transplant Congress
2B4 Expression on Human CD4+ Memory T Cells Is Associated With Functional Impairment
Emory Transplant Center, Emory University, Atlata, GA.
The SLAM family receptor 2B4 is expressed primarily on NK cells and memory CD8+ T cells. In prior studies, we found that 2B4 was upregulated…2015 American Transplant Congress
Lymphatic Endothelium Uniquely Enhances T Cell Migration to S1P
University of Maryland, Baltimore, MD.
Introduction: Sphingosine-1-phosphate (S1P) is a signaling sphingolipid that regulates cell egress from lymphoid and non-lymphoid tissues. While S1P has been described as a chemoattractant, its…
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