ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Long Term Outcomes With Alemtuzumab Induction Therapy for Deceased and Living Renal Transplant Recipients. A Single Center Experience

    P. Vaitla, U. Patel, A. Cruz, S. Guisti, A. Moiz, C.-S. Catherine, A. Cohen, G. Loss, H. Bohorquez, I. Carmody, T. Reichman, D. Bruce, S. Anders, J. Garces.

    Ochsner Clinic Foundation, New Orleans, LA.

    Background:Antibody induction therapy has been used for induction in up to 80% kidney transplant recipients according to United Network for Organ Sharing. It has been…
  • 2015 American Transplant Congress

    Effect of Everolimus on Cardiovascular Parameters in De Novo Kidney Transplant Recipients: 12-Month Results from the ELEVATE Study

    H. Holdaas,1 M. van der Giet,1 J. de Fijter,1 A. Speziale,2 C. Escrig,2 G. Junge,2 Z. Wang,3 J. Cruzado.1

    1For the ELEVATE Study, Oslo, Norway; 2Novartis, Basel, Switzerland; 3Novartis Corporation, East Hanover, NJ.

    Background: Long-term exposure to calcineurin inhibitors (CNIs) contributes to an unfavorable cardiovascular (CV) risk profile, including inferior renal allograft function and premature graft loss with…
  • 2015 American Transplant Congress

    Interferon-Free Sofosvir/Ribavirin Treatment Achieves Excellent Sustained Viral Response in Post Liver Transplant HCV Recipients

    M. Hamshow, K. Bortecen, R. Layman, A. Winnick, B. Gelb, G. Morgan, L. Teperman.

    Transplant Surgery, NYU Langone Medical Center,The Mary Lea Johnson Richards Organ Transplant Center, New York, NY.

    Purpose: HCV is the leading cause of end-stage liver disease, universally recurring in the post-transplant setting. Studies have shown disappointing results after first generation protease…
  • 2015 American Transplant Congress

    Basiliximab Induction With Delayed Tacrolimus Initiation up to 14 Days Post Liver Transplantation Maintains Excellent Clinical Outcomes While Preserving Renal Function

    J. Werth, W. Ally, D. Maluf, S. Pelletier.

    University of Virginia Health System, Charlottesville, VA.

    Background: Calcineurin inhibitors are frequently delayed to allow for recovery of renal function after transplantation; however, there is a paucity of literature supporting a delay…
  • 2015 American Transplant Congress

    Hospital Characteristics Mediate Variation in Cirrhosis Mortality in Transplant and Non-Transplant Facilities

    A. Mathur,1 A. Chakrabarti,2 K. Sheetz,2 J. Mellinger,3 M. Volk,3 N. Katariya,1 A. Singer,1 W. Hewitt,1 K. Reddy,1 A. Moss.1

    1Surgery, Mayo Clinic Arizona, Phoenix, AZ; 2Surgery, University of Michigan, Ann Arbor, MI; 3Medicine, University of Michigan, Ann Arbor, MI.

    Hospitals vary significantly in cirrhosis mortality. We aimed to determine whether hospital structural characteristics mediate this effect.Methods: We used 2009 data from the HCUP Nationwide…
  • 2015 American Transplant Congress

    Factors Associated With Rehospitalization and High Cost Among Health Plan Members Receiving Kidney Transplants

    E. Lee,1 Y. Zhou,2 B. Suehs,2 B. Franks,1 B. Kassman,1 J. Spalding,1 G. Thal.1

    1Astellas Scientific and Medical Affairs, Northbrook, IL; 2Comprehensive Health Insights, Humana, Louisville, KY.

    PurposeAims were to develop a claims-based algorithm to identify kidney transplant cases and to examine clinical and economic outcomes among health plan members undergoing kidney…
  • 2015 American Transplant Congress

    Effects of Heart and Lung Co-Transplantation Across a Full MHC Barrier in Miniature Swine

    M. Madariaga, P. Spencer, S. Michel, G. La Muraglia II, M. O'Neil, E. Mannon, C. Leblang, I. Rosales, R. Colvin, D. Sachs, J. Allan, J. Madsen.

    Transplantation Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

    Background: We have previously shown that tolerance of heart allografts across a full MHC barrier can be induced in miniature swine after a 12-day course…
  • 2015 American Transplant Congress

    Differential Expression and Function of ASC and Nlrp3 Inflammasome Adaptors in Hematopoietic Stem Cells (HSCs)

    A. Scheinok, R. Elahimehr, A. Shigeoka, S. Kasimsetty, D. McKay.

    Medicine, University of California San Diego, San Diego, CA.

    HSCs are activated by pattern recognition receptors (PRRs), which might provide novel targets for improved engraftment. How PRRs affect HSC engraftment after BM transplantation is…
  • 2015 American Transplant Congress

    Current Status of US Intestinal and Multivisceral Transplantation: An Analysis of the UNOS Intestine Transplant Registry

    J. Cai,1 A. Qing,2 G. Wu,3 M. Everly,1 P. Terasaki.1

    1Terasaki Foundation Lab, Los Angeles, CA; 2Lincoln High School, Stockton, CA; 3The 4th Military Medical University, Xi-An, China.

    The purpose of this study is to analyze the current status of US intestinal transplantation (IT). As of 9/19/2014, 2441 IT have been performed in…
  • 2015 American Transplant Congress

    Outcome of Renal Sparing Protocol in a Cross-Sectional Analysis After Heart Transplant

    J. Kobashigawa, M. Kittleson, P. Patel, F. Liou, S. Siddiqui, D. Chang, B. Azarbal, D. Ramzy, L. Czer, J. Patel.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Calcineurin inhibitors (CNIs) are the mainstay of immunotherapy after heart transplantation. Unfortunately CNIs are associated with renal dysfunction due to nephrotoxic side effects. The…
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