2015 American Transplant Congress
New Insights in Clinical and Genetic Determinants of Longitudinal Dose-Corrected CNI Exposure in Children After Renal Transplantation
Purpose: Calcineurin-inhibitors (CNI) have a narrow therapeutic index and dosing is difficult due to inter- and intra-individual variation in pharmacokinetics (PK). Polymorphisms in genes involved…2015 American Transplant Congress
Living Donor Transplant Rates in Children Are Declining
University of Virginia, Charlottesville, VA.
Living donor (LD) transplant rates have been declining since 2004 in adult candidates. We sought to determine if this trend is also occurring in pediatric…2015 American Transplant Congress
The Explore Transplant Program in GA: Is Historical Access to Transplantation Associated With Kidney Transplant Knowledge and Preparedness to Educate ERSD Patients?
1Emory University, Atlanta; 2University of California, Los Angeles.
IntroductionDialysis facilities play a key role in educating end stage renal disease patients on kidney transplantation (KTx). We aimed to investigate the association between historical…2015 American Transplant Congress
Can Gene-Expression Profiling Score Help Explain the Adverse Clinical Outcomes Seen in Gender-Mismatched Heart Transplants?
Background: Gene-expression profiling (GEP) testing, in conjunction with clinical assessment, is an established laboratory test intended to aid in the identification of acute cellular rejection…2015 American Transplant Congress
Boosting the Adaptive Immune Response Prevents the High Incidence of Herpes Zoster After Lung or Heart Transplantation
Purpose Primary varicella zoster virus (VZV) infection causes varicella and lifelong latent infection in ganglia from which it may reactivate leading to herpes zoster (HZ).…2015 American Transplant Congress
Can Post-Transplant C-Peptide Be Used as an Indicator of Pancreas Graft Failure?
Background: The OPTN Pancreas Transplantation Committee is attempting to define pancreas graft failure and performed a study to determine if C-peptide corresponds to pancreas graft…2015 American Transplant Congress
Donor Derived Transmission Events in 2014: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)
Background: The OPTN DTAC, a multidisciplinary committee, evaluates potential donor derived transmission events (PDDTE), including infections (I) & malignancies (M), to assess for donor transmitted…2015 American Transplant Congress
Decline in Estimated Glomerular Filtration Rate and Subsequent Risk of Graft Failure and Mortality Among Kidney Transplant Recipients
Purpose: Graft loss and death are generally late events after kidney transplantation, and trials designed to assess the impact of interventions on these outcomes are…2015 American Transplant Congress
Effective Long-Term Prophylaxis against De Novo Hepatitis B With Hepatitis B Vaccination in Pediatric Recipients of HbcAb-Positive Liver Grafts
Department of Surgery, Samsung Medical Center, Seoul, Korea.
Background) Controversy still exists concerning the use of livers from hepatitis B surface antigen-negative (HBsAg-)/hepatitis B core antibody-positive (HBcAb+) donors for liver transplantation (LT). We…2015 American Transplant Congress
Left Ventricular Assist Device–Associated Allosensitization — Clinical Implications
U.T.A.H. Cardiac Transplant Program, Salt Lake City, UT.
Purpose: Allosensitization has been recognized as a prognostic marker of worse outcome after transplant. It is unclear, however, whether sensitization events that take place shortly…
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