ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Outcomes of Hispanic Kidney Transplant Recipients Under a Cyclosporine Versus Tacrolimus Based Immunosuppression Regimen

    P. West-Thielke,1 M. Campara,2 A. Ladik,1 E. Terranova,2 E. Benedetti,1 J. Thielke.2

    1Surgery, University of Illinois, Chicago; 2Pharmacy Practice, University of Illinois, Chicago.

    Purpose: In 2005, an internal retrospective study at our institution showed a higher incidence of post transplant diabetes mellitus (PTDM) in our Hispanic kidney transplant…
  • 2015 American Transplant Congress

    Mycophenolate Dose Reductions Contribute to Suboptimal Graft Outcomes in Kidney Transplant Recipients

    K. Boyle, J. Fleming, D. Taber, K. Covert, J. Casale, C. Staino, N. Pilch, C. Mardis, H. Meadows, T. Srinivas, J. McGillicuddy, K. Chavin, C. Bratton, P. Baliga.

    Medical University of South Carolina, Charleston, SC.

    The purpose of this study was to analyze outcomes in patients with mycophenolate mofetil (MMF) dose reductions below doses proven to prevent rejection in a…
  • 2015 American Transplant Congress

    Alemtuzumab Induction Is Protective Against Acute Rejection in Kidney Recipients With Subtherapeutic Tacrolimus Concentrations

    K. Szempruch, R.-A. Lee, R. Dupuis, J. Deyo, T. Kozlowski.

    Transplant Surgery, University of North Carolina Hospitals, Chapel Hill, NC.

    Purpose: To determine the effect of attaining early therapeutic tacrolimus (TAC) trough concentrations on biopsy-proven acute rejection (BPAR) within 12 months post-transplantation in adult kidney…
  • 2015 American Transplant Congress

    Verification of OPTN Hepatocellular Carcinoma Recurrence Data

    J. George,1 K. Eddinger,1 D. Goldberg,2 M. Levine,3 P. Abt.3

    1Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA; 2Division of Gastroenterology, Hospital of the University of Pennsylvania, Philadelphia, PA; 3Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA.

    PURPOSE: OPTN data on HCC recurrence is increasingly utilized for a variety of studies; however, the accuracy of this data has not been examined. We…
  • 2015 American Transplant Congress

    Are We Missing Cardiovascular Disease in Children Awaiting Liver Transplant?

    C. Villa,1 E. Hahn,1 J. Bucuvalas,2 K. Campbell,2 R. Hirsch,1 M. Lake,2 A. Lorts.1

    1Heart Institute, Cincinnati Childrens Hospital, Cincinnati, OH; 2Pediatric Liver Care Center, Cincinnati Childrens Hospital, Cincinnati, OH.

    Background: Cirrhotic cardiomyopathy, characterized by low systemic vascular resistance, is increasingly recognized as a complication of end stage liver disease. Yet optimal strategies to screen…
  • 2015 American Transplant Congress

    Immunomonitoring By Virus-Specific T Cells After Pediatric Kidney Transplantation (IVIST01-Trial): Study Design and Status

    T. Ahlenstiel-Grunow,1,4 M. Sester,3 U. Sester,2 L. Pape.1,4

    1Pediatric Nephrology, Hannover Medical School, Hannover, Germany; 2Nephrology, Saarland University, Homburg (Saar), Germany; 3Virology, Saarland University, Homburg (Saar), Germany; 4Integrated Research and Treatment Center Transplantation, Hannover Medical School, Hannover, Germany.

    After kidney transplantation (Tx) immunosuppressive therapy causes an impaired cellular immune defense with an increased risk of viral complications. Virus-specific T cells (Tvis) correlate with…
  • 2015 American Transplant Congress

    Renal Cell Carcinoma in the Native Kidney in Dialysis and Kidney Transplantation Recipients. Different Entities?

    K. Yamaçake, W. Nahas, H. Kanashiro, R. Kato, A. Bull, I. Antonopoulos, R. Falci, A. Piovesan.

    Division of Urology, Renal Transplantation Unit, University of São Paulo, São Paulo, SP, Brazil.

    Purpose: Renal Cell Carcinoma (RCC) has a high incidence in patients with acquired cystic kidney disease (ACKD) due to hemodialysis. It has been reported that…
  • 2015 American Transplant Congress

    Clinical Use of Gene-Expression Profiling to Monitor for Rejection After Cardiac Transplantation – Which Patients and When?

    J. Teuteberg,1 M. Shullo,1 T. Wolf,2 P. Prasad,2 G. Ewald.3

    1University of Pittsburgh Medical Center, Pittsburgh, PA; 2CareDx, Inc., Brisbane, CA; 3Washington University, St. Louis, MO.

    Background: Gene-expression profiling (GEP), in place of endomyocardial biopsy, is increasing. GEP testing is intended for low-risk asymptomatic patients (pts); thus, the profile of pts…
  • 2015 American Transplant Congress

    Implementation of Evidence-Based Guidelines for Cytomegalovirus Prevention in Pediatric Solid Organ Transplantation

    L. Danziger-Isakov, T. Hemmelgarn, R. Kohli, D. Lazear, M. Lake, J. Goebel, C. Castleberry, J. Courter, S. Kacoshis, M. Schecter, D. Witte, E. Clark, J. Bucuvalas.

    Cincinnati Children's, Cincinnati.

    Optimal strategies to prevent cytomegalovirus (CMV) disease after pediatric solid organ transplantation (SOT) in a cost effective manner are uncertain. We evaluated the frequency of…
  • 2015 American Transplant Congress

    Noninvasive Diagnostic and Predictive Value in Renal Transplant Recipients by Measurement of Urine BCA-1

    D. Chen, J. Chen, W. Peng.

    Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Key Laboratory of Nephropathy, Zhejiang Province; Kidney Disease Immunology Laboratory, The Third Grade Laboratory, State Administration of Traditional Chinese.

    ObjectiveTo investigate the relationship between early-stage renal acute rejection and the level of BCA-1 in urine, explore the diagnostic value and noninvasive monitoring in early…
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