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American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Systematic Medical Record Review to Identify Safety Risks in Living Liver Donors

    B. Platt,5 D. Woods,5 R. Fisher,2 J. Guarrera,3 E. Pomfret,4 M. Simpson,4 A. Daud,1 T. Curtis,5 E. Reyes,5 E. Wymore,5 A. Skaro,1 D. Ladner.1

    1Northwestern University, Chicago, IL; 2Virginia Commonwealth University, Richmond, VA; 3Columbia University, New York, NY; 4Lahey Clinic, Boston, MA; 5CHS, Northwestern University, Chicago, IL.

    BACKGROUNDPrevention of adverse events (AEs) is important in Living Donor Liver Transplantation (LDLT), as these are healthy volunteers who undergo a major procedure with no…
  • 2015 American Transplant Congress

    Non-Inferiority of Graft Survival of Living Unrelated Kidney Transplant compared to Living Related Kidney Transplant as Analyzed by First Degree Relative

    A. Patel, M. Goggins, D. Kim, P. Rohini, L. Malinzak.

    Henry Ford Transplant Institute, Detroit, MI.

    The perceived advantage of donating a kidney directly to a family member is difficult to uncouple in the setting of voluntary exchange or other kidney…
  • 2015 American Transplant Congress

    Psychological Benefit After Living Kidney Donation: Is It a Myth?

    H. Maple, N. Mamode.

    Renal Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

    Introduction: The moral and ethical justification for living donation is provided by an assumed psychological benefit to the donor after donation. However, there are no…
  • 2015 American Transplant Congress

    Epidemiologic Change in Pulmonary Hypertension Patients Referred for Lung Transplantation Post Lung Allocation Score Implementation

    R. Loyaga-Rendon,1 B. Shelton,1 R. Reed,1 J. Tallaj,1 E. Diaz-Guzman,1 G. Heresi,2 J. Locke.1

    1Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL; 2Pulmonary Medicine, Cleveland Clinic Foundation, Cleveland, OH.

    Introduction: The lung allocation score (LAS) was designed and implemented in May 2005 to account for various measures of a candidate's health in an attempt…
  • 2015 American Transplant Congress

    Impact of Donor Age on Longterm Outcomes in Asian Kidney Transplant Recipients: A Multicenter Cohort Study

    K. Yoo,1 J. An,2 J.-H. Cho,3 C.-D. Kim,3 S.-K. Park,4 D.-W. Chae,5 Y. Oh,2 C. Lim,2 Y. Kim,1 Y. Kim,6 J. Lee.2

    1Internal Medicine, Seoul National University Hospital, Seoul, Korea; 2Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; 3Internal Medicine, Kyungpook National University Hospital, Daegu, Korea; 4Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; 5Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea; 6Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.

    Background The living donor kidney transplantation (LDKT) is well known for best treatment of end-stage renal disease. Recently, kidney transplantation from elderly living donor has…
  • 2015 American Transplant Congress

    Improving the Predictive Value of the Virtual Crossmatch: Is the C1Q Assay Needed?

    A. Colovai,1 C. Savchik,1 P. Masiakos,1 S. Calp-Inal,2 L. Kayler,3 E. Akalin.2

    1Transplant Immunology Laboratory, Montefiore Medical Center, Bronx, NY; 2Nephrology, Montefiore Medical Center, Bronx, NY; 3Surgery, Montefiore Medical Center, Bronx, NY.

    The criteria for reporting unacceptable HLA antigens of renal transplant candidates differ greatly between transplant centers. In the attempt to refine these criteria, the experience…
  • 2015 American Transplant Congress

    Single Nucleotide Polymorphisms (SNPs) Associated With Acute Rejection in European American Kidney Transplant Recipients: A Genome Wide Association Study (GWAS)

    A. Israni,1 C. Dorr,1 M. Miller,2 D. Schladt,1 K. Sanghavi,3 A. Muthusamy,1 R. Remmel,3 W. Guan,4 B. Wu,4 W. Oetting,3 P. Jacobson,3 A. Matas,5 For DeKAF Genomics & GEN03 Investigators.1

    1Medicine, MMRF, Hennepin County Medical Center, Minneapolis, MN; 2Psychology, University of MN, Minneapolis, MN; 3Pharmacy, University of MN, Minneapolis, MN; 4Biostatistics, University of MN, Minneapolis, MN; 5Surgery, University of MN, Minneapolis, MN.

    Purpose: Acute rejection (AR) is associated with increased risk of allograft loss. Therefore, we conducted a GWAS to determine SNPs associated with AR in a…
  • 2015 American Transplant Congress

    Use of RNA Sequencing for Discovery of Markers of Accommodation in Surveillance Biopsies from Recipients of an ABO-Incompatible Renal Transplant

    A. McLean,2 K. Dominy,1 A. Sosinsky,1 M. Mueller,1 J. Galliford,2 T. Cook,1,2 C. Roufosse.1,2

    1Imperial College, London, United Kingdom; 2Imperial College Healthcare NHS Trust, London, United Kingdom.

    Recipients of an ABO incompatible transplant have circulating anti-AB antibodies, A and/or B antigens expressed on endothelium and usually C4d deposition on the endothelium, yet…
  • 2015 American Transplant Congress

    Human Mesenchymal Stromal Cells Improve Survival and Function of Pancreatic Islets by Cell-to-Cell Contact

    E. Montanari,1 R. Mahou,1,2 S. Passemard,2 F. Noverraz,2 P. Morel,1 R. Meier,1 D. Bosco,1 J. Seebach,3 C. Wandrey,2 S. Gerber,2 C. Gonelle-Gispert,1 L. Buhler.1

    1Department of Surgery, Cell Isolation and Transplantation Center, Geneva University Hospitals and Medical Faculty, Geneva, Switzerland; 2Institut d'Ingénierie Biologique et Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; 3Division of Immunology and Allergy, Geneva University Hospitals and Medical Faculty, Geneva, Switzerland.

    Background and Aim:The aim of this study was to evaluate the survival and function of human pancreatic islets co-encapsulated with human Mesenchymal Stromal Cells (MSC)…
  • 2015 American Transplant Congress

    Interactions Between Platelets and Liver Sinusoidal Endothelial Cells Initiate Liver Regeneration

    J. Meyer,1,2 E. Lejmi,2 P. Fontana,2,3 P. Morel,1,2 C. Gonelle-Gispert,2 L. Bühler.1,2

    1Division of Digestive and Transplantation Surgery, University Hospitals of Geneva, Geneva, Switzerland; 2Geneva Medical School, Geneva, Switzerland; 3Division of Angiology and Haemostasis, University Hospitals of Geneva, Geneva, Switzerland.

    ObjectivesPlatelets and liver sinusoidal endothelial cells (LSEC) were shown to be important contributors to liver regeneration. Several recent studies suggested that their interactions might be…
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