ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    DSA Monitoring in Kidney Transplant Recipients

    F. Pean,1 M. Cooper,1 J. Verbesey,1 A. Gilbert,1 B. Javaid,1 R. Mohammed,1 O. Timofeeva,2 J. Moore,1 K. Cruz,1 R. Ghasemian,1 T. Fishbein,1 M. Grafals.1

    1Medstar Georgetown Transplant Institute, Georgetown University, Washington, DC; 2Clinical Laboratory and Histocompatibility, Georgetown University, Washington, DC.

    Introduction: The development of DSA monitoring is a new technique to detect antibodies in kidney transplant recipients. Data has shown that development of DSA post…
  • 2015 American Transplant Congress

    Increased Length of Stay After Heart Transplant: What Are the Risk Factors?

    A. Velleca, M. Kittleson, N. Perry, J. Patel, F. Liou, S. Siddiqui, J. Rush, D. Ramzy, L. Czer, D. Chang, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: Initial hospital length of stay following heart transplant is variable. The longer the hospital stay, the increased cost related to the surgery. This will…
  • 2015 American Transplant Congress

    Outcome of Invasive Aspergillosis in Liver Transplant Recipients Under Current Antifungal Therapy

    U. Herden, E. Grabhorn, B. Nashan, L. Fischer.

    University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

    Introduction: Invasive aspergillosis is a rare but severe complication following liver transplantation (LTX) with reported mortality rates up to 100%. Our purpose was to investigate…
  • 2015 American Transplant Congress

    Orthotopic Transplantation of a Tissue Engineered Skin Graft in Athymic Mice

    N. Nayakawde, P. Patil, K. Methe, M. Olausson.

    Surgery, Gothenburg University, Gothenburg, Vastra Gotaland, Sweden.

    Background: Tissue engineered (TE) skin offers promising alternative treatment in wound healing of acute and chronic skin injuries. Limited autografts from donor skin and risks…
  • 2015 American Transplant Congress

    Establishment of Diabetes Modeling in Common Marmoset

    W. Yuan,1 S. Fukuda,1 T. Inoue,2 D. Chujo,1 H. Okochi,1 E. Sasaki,2 M. Shimoda.1

    1National Center for Global Health and Medicine, Tokyo, Japan; 2Central Institute for Experimental Animals, Kawasaki, Japan.

    Background:Diabetic nonhuman primates (NHPs) are considered as the good models for both diabetes mellitus research and islet transplantation research safely into clinical applications. However, there…
  • 2015 American Transplant Congress

    Ischemia-Induced Endoplasmic Reticulum Stress Regulates Autophagy to Determine the Severity of Liver Ischemia Reperfusion Injury

    H. Zhou,1,2 J. Zhu,1 S. Yue,1 R. Busuttil,1 J. Kupiec-Weglinski,1 Y. Zhai.1

    1The Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA; 2Liver Transplant Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

    Both endoplasmic reticulum (ER) stress and autophagy have been implicated in the pathogenesis of ischemia and reperfusion injury (IRI). As essential cellular stress responses against…
  • 2015 American Transplant Congress

    Enhancing Kidney Function Following DCD Donation With Thrombolytic Therapy: A Preliminary Report of a Multicenter Prospective Quasi-Blinded Randomized Trial

    K. Woodside,1 D. Goldfarb,2 J. Rabets,2 E. Sanchez,1 D. Lebovitz,3 J. Schulak,1 J. Fung,2 B. Eghtesad.2

    1Transplant Institute, University Hospitals Case Medical Center, Cleveland, OH; 2Transplant Center, Cleveland Clinic, Cleveland, OH; 3LIfebanc, Cleveland, OH.

    Kidneys from donors following cardiac death (DCD) are at risk for inferior outcomes, possibly due to microthrombi and additional warm ischemia. We describe an organ…
  • 2015 American Transplant Congress

    100 Protocol Renal Allograft Biopsies at 10 Years: First Look at the Tacrolimus Era

    M. Stegall,1 W. Park,1 F. Cosio,2 L. Cornell.3

    1Transplant Surgery, Mayo Clinic, Rochester, MN; 2Medicine, Mayo Clinic, Rochester, MN; 3Laboratory Medicine, Mayo Clinic, Rochester, MN.

    This study examined late renal allograft injury in the Tacrolimus era in 10-yr protocol biopsies (Bx).Methods One hundred 10-yr protocol allograft bx were assessed using…
  • 2015 American Transplant Congress

    Morphometry of the Epithelial-Mesenchymal Transition (EMT) in Subsequent Biopsies from Transplanted Kidney

    R. Świder, A. Perkowska-Ptasińska, A. Stachurska, J. Fabijańska-Mitek, R. Zagożdżon, S. Gruca, J. Gołąb, M. Durlik.

    Department of Transplantation Medicine, Medical University, Warsaw, Poland; Department of Transplantation Medicine, Medical University, Warsaw, Poland; Department of Immudohaematology, Centre of Postgraduate Medical Education, Warsaw, Poland; Department of Immudohaematology, Centre of Postgraduate Medical Education, Warsaw, Poland; Department of Immunology, Medical University, Warsaw, Poland; Department of Immunology, Medical University, Warsaw, Poland; Department of Immunology, Medical University, Warsaw, Poland; Department of Transplantation Medicine, Medical University, Warsaw, Poland.

    EMT plays the principal role in the pathogenesis of IF/TA as a consequence in the failure of a transplanted kidney. Many facts suggest that the…
  • 2015 American Transplant Congress

    Down-Regulation of Autophagy Correlates With Increased Apoptosis in the Kidney, But Not in the Liver, of Brain Dead Rats

    A. van Erp,1 R. Rebolledo,3 P. Ottens,1 J. Pirenne,2 H. Leuvenink,1 J.-P. Decuypere.2

    1Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Department of Microbiology and Immunology, Catholic University Leuven, Leuven, Belgium; 3Department of Surgery, University of Chile, Santiago, Chile.

    Organs from brain dead donors have inferior quality and show higher rejection rates after transplantation compared to living donors. Brain death (BD) in the donor…
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