2015 American Transplant Congress
Longitudinal Multi-Omic Profiling of Genes and Pathways Underlying Cardiac Allograft Rejection
Our ability to treat cardiac allograft rejection in both acute and chronic states is typically limited by poor existing biomarkers to predict the occurrence of…2015 American Transplant Congress
Perturbation of Polyomavirus Nephropathy-Specific Gene Expression in Kidney Allografts
Polyomavirus nephropathy (PVAN) is a common cause of kidney allograft dysfunction and loss. Microscopic observations of PVAN are similar to T-cell mediated rejection (TCMR), with…2015 American Transplant Congress
Defining and Directing T Cell Subsets Involved in Rejection of Vascularized Composite Allografts
Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD.
Purpose: Wider utilization of VCA is hampered by the need for long-term immunosuppression. Barriers to more targeted immunosuppression in VCA include (1) limited knowledge of…2015 American Transplant Congress
Is Ex Vivo Liver Perfusion a Safe Alternative to Cold Static Storage for the Preservation of Standard Criteria Grafts?
Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.
Objective: Subnormothermic ex vivo liver perfusion (SNEVLP) has recently attracted great interest in the field of organ preservation for marginal grafts. However, data is lacking…2015 American Transplant Congress
The 20S Proteasome Is Active in Apoptotic Nanovesicles and Controls Anti-LG3 Antibody Production
Humoral autoreactivity to apoptotic cells and perlecan/LG3, a proteoglycan fragment released by apoptotic cells, predicts poor allograft outcomes in renal transplant patients. How apoptotic cells…2015 American Transplant Congress
Pancreas Transplant Sera Improves the Function and Proliferation of Endothelial Cells
Transplant Services, Allegheny General Hospital, Pittsburgh, PA.
Pancreas transplantation (Tx) allows for the study of diabetes by examining the reversal of the disease. Previously, we observed that after pancreas Tx many patients'…2015 American Transplant Congress
High Kidney Donor Profile Index (KDPI) Correlates With Calculated Pulsatile Perfusion (PP) Resistance Index (RI) and Delayed Graft Function (DGF)
Surgery/Transplant, The Ohio State University Medical Center, Columbus, OH.
Background: Deceased donor (DD) kidney quality is now being determined by calculating the Kidney Donor Profile Index (KDPI). Calculated kidney vascular resistance index (RI) during…2015 American Transplant Congress
One Year Outcomes and Quality of Life Measurements in 127 Extended Criteria Donor Recipients- A Single Centre Comparative Study
Introduction: Expanded criteria donors (ECDs) are those aged over 60 or 50-59 with 2 of: hypertension, death from cerebrovascular cause or terminal serum creatinine over…2015 American Transplant Congress
Toxicity Driven Conversion to Belatacept in Kidney Transplant Recipients
Yale-New Haven Transplantation Center, New Haven, CT.
Purpose: Evaluate the result of conversion to belatacept from calcineurin inhibitor (CNI) or TOR inhibitor based regimens due to toxicities in kidney transplant recipients (KTR).Methods:…2015 American Transplant Congress
Infectious Complications in ABO Incompatible Kidney Transplantation Recipient According to the Rituximab Dose
BackgroundDesensitization with rituximab and intravenous immunoglobulin improves ABO incompatible (ABOi) kidney transplantation (KT) outcomes. However, infections have been noted in association with rituximab administration. In…
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