ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Functional Decline in Liver Transplant Candidates: Results from the Functional Assessment in Liver Transplantation (FrAILT) Study

    J. Lai, K. Covinsky, J. Dodge, S. Sen, S. Feng.

    UCSF, San Francisco, CA.

    Background: Cirrhosis is characterized by sarcopenia and malnutrition, leading to progressive functional decline. No studies have objectively measured physical functional decline in cirrhotics awaiting liver…
  • 2015 American Transplant Congress

    Effectiveness of Protocol-Driven Induction Therapy in Adult Kidney Transplant Recipients

    J. Casale, J. Fleming, D. Taber, C. Staino, K. Boyle, K. Covert, N. Pilch, H. Meadows, C. Mardis, K. Chavin, C. Bratton, J. McGillicuddy, T. Srinivas, P. Baliga.

    MUSC, Charleston, SC.

    Background: Induction therapy significantly improves graft outcomes in kidney transplantation, but the optimal agent based on patient characteristics and immunologic risk is unknown. While many…
  • 2015 American Transplant Congress

    Evaluation of Donor-Specific Antibodies Through 7 Years With Belatacept in BENEFIT and BENEFIT-EXT

    R. Bray,1 H. Gebel,1 R. Townsend,2 U. Meier-Kriesche,2 C. Larsen.1

    1Emory University, Atlanta; 2Bristol-Myers Squibb, Lawrenceville.

    Purpose: The development of donor-specific antibody (DSA) is linked to an increased risk of antibody-mediated rejection and graft failure. The 3 year intent-to-treat results from…
  • 2015 American Transplant Congress

    Enhanced Requirement for TNF Signaling on Low Affinity Memory CD8+ T Cells During Heterologous Immunity

    S. Krummey,1 C.-W. Chen,1 D. Liu,1 M. Wagener,1 B. Evavold,2 C. Larsen,1 M. Ford.1

    1Emory Transplant Center, Emory University, Atlanta, GA; 2Microbiology and Immunology, Emory University, Atlanta, GA.

    Heterologous immunity, defined as a process during which microbe-specific T cells cross-react with allogeneic antigen and mediate graft rejection, is recognized as a significant barrier…
  • 2015 American Transplant Congress

    Survival Benefit of Kidney Transplant Among HIV+ Waitlist Candidates

    J. Locke,1 S. Gustafson,2 C. Durand,3 J. Snyder,2 B. Shelton,1 R. Reed,1 P. MacLennan,1 S. Mehta,1 A. Nellore,1 D. Segev.2,3

    1University of Alabama, Birmingham, AL; 2Scientific Registry of Transplant Recipients (SRTR), Minneapolis Medical Research Foundation, Minneapolis, MN; 3Johns Hopkins University, Baltimore, MD.

    Chronic diseases, such as end-stage renal disease (ESRD), are now the leading causes of death among HIV+ patients. Multiple studies have demonstrated the efficacy of…
  • 2015 American Transplant Congress

    Neighborhood Poverty Modifies Gender Disparities in Kidney Transplant Outcomes

    T. Purnell, X. Luo, A. Massie, D. Crews, L. Cooper, D. Segev.

    Johns Hopkins, Baltimore.

    Earlier studies report mixed findings comparing transplant outcomes in women versus men, and little is known about the association of socioeconomic status (SES) with gender…
  • 2015 American Transplant Congress

    Outcomes of Kidney Transplantation of ABO- and Crossmatch-Incompatible Recipient-Donor Pairs Entered in Kidney Paired Donation Program

    D. Dadhania, M. Charlton, M. Aull, R. Friedlander, T. Muthukumar, J. Lee, M. Goris, D. Serur, S. Kapur, V. Sharma.

    Transplantation Medicine, Weill Cornell Medical Center, New York, NY.

    Kidney Paired Donation (KPD) enables ABO-incompatible (ABOI) and crossmatch-incompatible (XMI) patients to undergo transplantation using a 'more compatible' donor. Identification of factors that predict early…
  • 2015 American Transplant Congress

    Pregnancy Outcomes in Kidney Recipients With Longer Transplant to Conception Intervals

    S. Constantinescu,1,2 L. Coscia,2 D. Armenti,2 P. Axelrod,1 M. Ghanta,1 S. Rao,1 M. Moritz.2,3

    1Temple University School of Medicine, Philadelphia; 2National Transplantation Pregnancy Registry, Gift of Life Institute, Philadelphia; 3Lehigh Valley Heath Network, Allentown.

    The purpose of this study was to analyze pregnancy outcomes in female kidney transplant recipients with transplant to conception intervals (TCI) after the recommended 2…
  • 2015 American Transplant Congress

    Living Donor Liver Transplantation for Biliary Atresia has Equivalent Survival and Shorter Waiting Time Compared to Deceased Donor Liver Transplantation

    S. Alexopoulos,1 V. Nekrasov,1 L. Matsuoka,1 K. Chouliaras,2 Y. Genyk.1

    1Department of Surgery, Keck Medical Center of USC, Los Angeles, CA; 2Department of Surgery, Wake Forest University, Winston-Salem, NC.

    Purpose: To determine the benefit of living donor liver transplantation (LDLT) compared to deceased donor liver transplantation (DDLT) in the treatment of end stage liver…
  • 2015 American Transplant Congress

    Cumulative Incidence, Risk Factors for and Impact on Survival of Severe Chronic Kidney Disease After Intestinal Transplantation: Analysis of the SRTR Database

    G. Huard,1 K. Iyer,1 J. Moon,1 L. Schwartz,1 J. Doucette,2 V. Nair,1 T. Schiano.1

    1Recanati-Miller Transplant Institute, Mount Sinai Hospital, New York, NY; 2Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.

    Background: Patient and graft survival rates after intestinal transplantation (ITx) have improved. More ITx recipients achieve long-term survival and are at risk for severe chronic…
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