2015 American Transplant Congress
Normothermic Machine Perfusion (NMP) on Discarded Human Livers: The First Model in the US
Cleveland Clinic, Cleveland, OH.
The benefit of NMP preservation has been reported in a number of animal studies. Herein we describe safety, feasibility and effectiveness of NMP on discarded…2015 American Transplant Congress
Stimulating Protease Inhibitor 9 Expression By Human Regulatory T Cells Improve Homeostasis
Renal/ Transplantation Research Center, Brigham and Women's Hospital, Boston, MA.
In this study, we show for the first time the key role of a protease inhibitor PI9 in human regulatory T cells (Tregs) homeostasis. Recent…2015 American Transplant Congress
Cytotoxic CD8 T Cell Recognition of Acquired, Intact MHC Alloantigen On Host Dendritic Cells Promotes Acute Allograft Rejection
University of Cambridge, Cambridge, United Kingdom.
IntroductionAlthough there is increasing evidence that recipient DCs can acquire intact MHC class I by trogocytosis from parenchymal cells, the functional relevance of the 'semi-direct'…2015 American Transplant Congress
Natural History of Anti- Human Leukocyte Antigen Antibodies After Hear Transplant
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: The natural history of the production of circulating antibodies has not yet been clearly established. Recent technology has allowed for the improved detection of…2015 American Transplant Congress
Urinary CXCL10 Independently Improves the Noninvasive Diagnosis of Antibody-Mediated Kidney Allograft Rejection
The urinary levels of CXCL9 and CXCL10 can noninvasively diagnose T cell-mediated rejection (TCMR) of renal allografts. Their performance as diagnostic/prognostic markers of antibody-mediated rejection…2015 American Transplant Congress
The Impact of a Desensitization Protocol Using Plasmapheresis and Intravenous Immunoglobulin On Graft Outcome in Kidney Recipients With Donor Specific Anti-HLA Antibodies
Hospital Geral de Fortaleza, Fortaleza, Brazil.
Introduction: Kidney transplantation in patients with donor-specific anti-HLA antibodies (DSA) has been associated with a worse prognosis. The high cost, infectious complications and conflicting results…2015 American Transplant Congress
Robotic Kidney Transplantation in Obese Recipients Can Lead to Superior Outcomes in Terms of Wound Infection and Graft Survival
Surgery, Division of Transplantation, University of Illinois at Chicago, Chicago, IL.
IntroductionTraditionally kidney transplantation (KT) in obese recipients has been associated with high rates of surgical site infections (SSI). We hypothesize that robotic kidney transplantation (RKT)…2015 American Transplant Congress
Optimal Induction Therapy (IT) in Pancreas After Kidney Transplantation (PAK) According to Type of Kidney (kd) Donor and Patient Risk – A Registry Analysis
1University of Arizona, Tucson, AZ; 2University of Arizona, Tucson, AZ.
Purpose: Best IT in PAK recipients (rec) according to type of kd donor (LD vs. DD) and rec risk has not been determined.Methods: Using the…2015 American Transplant Congress
Tolerance to Graft A-Antigens Following ABO-Incompatible Heart Transplantation (HTx) in a Blood Group A-Transgenic Mouse Model
Purpose: ABOi HTx can be performed safely in infants when ABO antibody (Ab) levels are low or absent. Following ABOi HTx, immune tolerance develops to…2015 American Transplant Congress
The Effect of Rituximab Therapy on Regulatory B Cell and Prevention of Chronic Antibody Mediated Rejection in Kidney Transplantation Recipients
Urology, Tokyo Women's Medical University, Tokyo, Japan.
We previously reported that a single administration of low dose rituximab (RIT) before kidney transplant reduced the incidence rate of chronic antibody mediated rejection (CAMR)…
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