ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Pregnancy Outcomes in Kidney Recipients With Longer Transplant to Conception Intervals

    S. Constantinescu,1,2 L. Coscia,2 D. Armenti,2 P. Axelrod,1 M. Ghanta,1 S. Rao,1 M. Moritz.2,3

    1Temple University School of Medicine, Philadelphia; 2National Transplantation Pregnancy Registry, Gift of Life Institute, Philadelphia; 3Lehigh Valley Heath Network, Allentown.

    The purpose of this study was to analyze pregnancy outcomes in female kidney transplant recipients with transplant to conception intervals (TCI) after the recommended 2…
  • 2015 American Transplant Congress

    Living Donor Liver Transplantation for Biliary Atresia has Equivalent Survival and Shorter Waiting Time Compared to Deceased Donor Liver Transplantation

    S. Alexopoulos,1 V. Nekrasov,1 L. Matsuoka,1 K. Chouliaras,2 Y. Genyk.1

    1Department of Surgery, Keck Medical Center of USC, Los Angeles, CA; 2Department of Surgery, Wake Forest University, Winston-Salem, NC.

    Purpose: To determine the benefit of living donor liver transplantation (LDLT) compared to deceased donor liver transplantation (DDLT) in the treatment of end stage liver…
  • 2015 American Transplant Congress

    Cumulative Incidence, Risk Factors for and Impact on Survival of Severe Chronic Kidney Disease After Intestinal Transplantation: Analysis of the SRTR Database

    G. Huard,1 K. Iyer,1 J. Moon,1 L. Schwartz,1 J. Doucette,2 V. Nair,1 T. Schiano.1

    1Recanati-Miller Transplant Institute, Mount Sinai Hospital, New York, NY; 2Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.

    Background: Patient and graft survival rates after intestinal transplantation (ITx) have improved. More ITx recipients achieve long-term survival and are at risk for severe chronic…
  • 2015 American Transplant Congress

    Small RNA Sequencing-Enabled Discovery of Circulating Extracellular MicroRNAs as Noninvasive Biomarkers of Liver Allograft Status

    H. Yang,1 T. Muthukumar,1 K. Akat,2 D. Briskin,2 T. Tuschl,2 M. Suthanthiran.1

    1Weill Cornell Medical Center, New York; 2Rockefeller University, New York.

    MicroRNAs are ideal candidates as blood-based biomarkers. Comprehensive profiling of microRNAs is challenging. We overcame the existing challenges by developing robust protocols for isolation of…
  • 2015 American Transplant Congress

    Patients With Severe and Morbid Obesity Benefit from Deceased Donor Kidney Transplant

    A. Nishio Lucar,1 J. Ma,2 G. Vranic,1 D. Keith.1

    1Medicine, University of Virginia, Charlottesville, VA; 2Biostatistics, University of Virginia, Charlottesville, VA.

    More than one in three Americans are obese yet obesity is considered a relative and sometimes absolute contraindication to kidney transplant. Previous studies suggest that…
  • 2015 American Transplant Congress

    Reasons for Match Offer Refusals and Efforts to Reduce Them in the OPTN/UNOS Kidney Paired Donation Pilot Program (KPDPP)

    R. Leishman,1 D. Stewart,1 A. Kucheryavaya,1 L. Robbins Callahan,1 T. Sandholm,2 M. Aeder.3

    1UNOS, Richmond, VA; 2Carnegie Mellon Univ, Pittsburgh, PA; 3Univ Hosp Case Med Ctr, Cleveland, OH.

    Background: The OPTN/UNOS KPDPP has been finding 2-way, 3-way, and chain exchanges since Oct 2010. Though the number of pairs entered, matches found, and transplants…
  • 2015 American Transplant Congress

    Changes in Acceptances Patterns Under Share 35

    K. Washburn, E. Edwards, A. Harper.

    University of Texas HSC, San Antonio, TX; UNOS, Richmond, VA.

    The Share 35 policy was implemented June 2013 with intent of directing to livers to the sickest patients with the highest mortality and presumably shortest…
  • 2015 American Transplant Congress

    Closing the Knowledge Gap: The Successful Launch of an Interactive Website Dedicated to Information on Living Kidney Donor Transplantation

    D. Slaats,1 W. Zuidema,1 J. van de Wetering,1 D. Hesselink,1 T. Terkivatan,2 M. Betjes.1

    1Internal Medicine, Division of Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands; 2Surgery, Division of Transplant Surgery, Erasmus MC, Rotterdam, Netherlands.

    Introduction. The internet is increasingly used to find reliable information about living kidney donation (LKD) and transplantation (LKT). Therefore, an easily accessible, interactive website was…
  • 2015 American Transplant Congress

    MicroRNA (miR) 144 Dysregulates TGFβ Signaling Cascade and Contributes to Development of BOS Following Human Lung Transplantation

    Z. Xu,1 S. Ramachandran,1 D. Nayak,1 M. Gunasekaran,1 E. Trulock,1 R. Hachem,1 D. Kreisel,1 T. Mohanakumar.1

    1Surgery, Washington Univ Sch Med, St. Louis, MO; 2Medicine, Washington Univ Sch Med, St. Louis, MO.

    Background: Bronchiolitis Obliterans Syndrome (BOS) is characterized by a fibroproliferative cascade that is not amenable to current treatment regimens and remains the major impediment for…
  • 2015 American Transplant Congress

    Immunological Aspects of Iron Overload in Heart and Kidney Transplantation

    T. Resch,1 S. Ebner,1 P. Ritschl,1 M. Ashraf,1 C. Fabritius,1 A. Brunner,2 V. Nguyen,1 J. Günther,1 J. Pratschke,3 K. Kotsch.1

    1Department of Surgery, Medical University Innsbruck, Innsbruck, Austria; 2Department of Pathology, Medical University Innsbruck, Innsbruck, Austria; 3Department of Surgery, Charité, Berlin, Germany.

    Background: Clinical data suggest that iron (Fe) overload deleteriously affects graft survival after heart (HTX) and kidney transplantation (KTX) but possible immunologic mechanisms underlying this…
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