ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    A Discrete Choice Experiment to Explore Patients' Preferences for Kidney Transplant Monitoring by Video-Conferencing

    S. Brunet-Houdard,1 M. Giral,2 S. Gaboriau,2 A. Meurette,2 P. Daguin,2 P. Tessier.3

    1UEME, SIMEES, Tours University Hospital, Tours, France; 2Nantes University Hospital, Nantes, France; 3EA 4275, Nantes University, Nantes, France.

    INTRODUCTIONAn experiment to assess the clinical outcomes and the economic efficiency of a videoconferencing system for the renal transplant patient's monitoring is currently under way…
  • 2015 American Transplant Congress

    Does Transversus Abdominis Plane Block Reduce Opioid Analgesic Requirements in the Post-Operative Period in Renal Transplant Recipients?

    F. Afridi,1 R. Coates,1 S. Wright,2 J. French,1 D. Talbot,1 S. Rita.2

    1Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, United Kingdom; 2Department of Anesthesia, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, United Kingdom.

    Introduction: Renal transplant recipients are a challenge where pain management is concerned. The theory that transversus abdominis plane (TAP) block provides additional analgesic benefit reducing…
  • 2015 American Transplant Congress

    Identification of miRNAs Associated With Induced Tolerance to Allografts

    M. Vitalone, L. Wei, C. Esquivel, S. Busque, O. Martinez, S. Krams.

    Surgery-Transplantation, Stanford University School of Medicine, Stanford, CA.

    Introduction: Although the liver is less immunogenic than other solid organs, most liver transplant recipients receive lifelong immunosuppression. Total lymphoid irradiation (TLI) is part of…
  • 2015 American Transplant Congress

    Phenotypic Personalized Medicine: Mechanism-Independent Convergence Into Target Serum Tacrolimus Levels for Optimized Liver Transplant Immunosuppression

    A. Zarrinpar,1 A. Silva,2 D.-K. Lee,3 N. Datta,1 C.-M. Ho,2 D. Ho.3

    1Surgery-Division of Liver and Pancreas Transplantation, UCLA, Los Angeles, CA; 2Mechanical Engineering, UCLA, Los Angeles, CA; 3Bioengineering, and Oral Biology and Medicine, UCLA, Los Angeles, CA.

    PURPOSE:Immunosuppressive drugs such as tacrolimus have narrow therapeutic ranges and their dosing variability necessitates intensive drug monitoring. This study aimed to use Feedback System Control…
  • 2015 American Transplant Congress

    Pre-Transplant Levels of TFH cell-Inducing Pro-Inflammatory Cytokines Correlate With DSA Formation After Kidney Transplantation

    C. Macedo,1 K. Hadi,1 B. Elinoff,1 M. Marrari,1 A. Zeevi,1 B. Ramaswami,1 G. Chalasani,1 A. Shields,2 R. Alloway,3 E. Woodle,2 F. Lakkis,1 D. Metes.1

    1Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh; 2Surgery, University of Cincinnati College of Medicine, Cincinnati; 3Internal Medicine-Nephrology, University of Cincinnati College of Medicine, Cincinnati.

    Donor-specific anti-HLA antibodies (DSA) represent an important biomarker for acute rejection and are a major cause of long-term graft failure after kidney transplantation (KTx). The…
  • 2015 American Transplant Congress

    Characterization of Natural T Effector Memory Cells Specific for Collagen type V, k-α-1-Tubulin and Vimentin

    J. Sullivan,1 D. Wilkes,2 T. Mohanakumar,3 W. Burlingham.1

    1Surgery, University of Wisconsin, Madison, WI; 2Medicine, Indiana University, Indianapolis, IN; 3Surgery, Washington University, St. Louis, MO.

    Background: Injury and repair processes are highly controlled, common occurrences of healthy tissue remodeling. During this process, cellular antigens that are not normally exposed to…
  • 2015 American Transplant Congress

    CD28 Saturation by FR104, a Non-Activating CD28 Antagonist Fab in a Non-Human Primate Cardiac Allograft Model

    W. Sun,1 A. Azimzadeh,1 G. Braileanu,1 T. Zhang,1 D. Amoako,1 L. Burdorf,1 B. Vanhove,2 R. Pierson III.

    1Dept of Surgery, University of Maryland School of Medicine, Baltimore, MD; 2INSERM U643, Nantes, France.

    Background: Targeting CD28 costimulation pathway with a selective antagonist is a promising approach in tolerance induction. The extent to which novel therapeutic antibodies reach their…
  • 2015 American Transplant Congress

    Does PTH Play a Role in Post Kidney Transplant Leukopenia?

    R. Dhawan, L. Shin, K. Lee, B. Duong, L. Aguirre, C. Parke, S. Alexopoulos, M. Smogorzewski, A. Gomez, E. Mariscal, L. Matsuoka, Y. Qazi.

    Division of Transplantation, University Of Southern California. Keck Med Center, Los Angeles, CA.

    Aim : Recent data suggests a role of Parathyroid hormone (PTH) on hematopoietic stem cell progenitor cells(HSPCs)[1,2]. The purpose of the study was determine the…
  • 2015 American Transplant Congress

    The Use of a Nurse Practitioner Led Transitional Diabetes Clinic Following Transplantation

    N. Cardinez, P. Segal, S. Trohonel.

    Endocrinology Department, University Health Network - Toronto General Hospital, Toronto, ON, Canada.

    The incidence of new onset diabetes after transplant [NODAT] ranges from 2% to 53%, also Type1 [T1DM] and Type 2 [T2DM] diabetes are common in…
  • 2015 American Transplant Congress

    Comparative Survival Benefits and Costs of an Eplet and Broad Antigen Based Matching System in Deceased Donor Kidney Transplant Allocation Among Indigenous Australians

    H. Do Nguyen,1 G. Wong,2,3 J. Chapman,2 J. Craig,2,3 L. D'Orsogna,4 W. Lim.1,5

    1School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia; 2Nephrology, The Children's Hospital at Westmead, Sydney, New South Wales, Australia; 3School of Medicine, University of New South Wales, Sydney, New South Wales, Australia; 4Clinical Immunology, Royal Perth Hospital, Perth, Western Australia, Australia; 5Renal Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.

    Aim: To compare the benefits and costs of incorporating an eplet-based matching algorithm to the current allocation of deceased donor kidneys to indigenous Australians.Background: The…
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