2015 American Transplant Congress
Clinical Outcomes of Living Kidney Donors With Medullary Sponge Kidney
Nephrology and Hypertension, Mayo Clinic, Rochester, MN.
Background: Patients with medullary sponge kidney (MSK) commonly encounter recurrent nephrolithiasis. The objective of this study was to assess the clinical and safety outcomes of…2015 American Transplant Congress
Histologic Patterns of C4d Associated With Acute Antibody Mediated Rejection of the Lung Allograft
Pathology, UT Southwestern Medical Center, Dallas, TX.
The diagnosis of antibody mediated rejection (AMR) of the lung allograft still represents a diagnostic challenge for pathologist and transplant physicians alike. The morphologic and…2015 American Transplant Congress
Bortezomib-Based Multi-Modality Protocol for Donor-Specific Antibody Treatment in Lung Transplant Recipients
Duke University Hospital, Durham, NC.
Background Donor specific antibodies (DSAs) after lung transplant have been implicated in the development of chronic lung allograft dysfunction and mortality. The ideal treatment strategy…2015 American Transplant Congress
Does the Site Or Etiology of Renal Artery Stenosis Influence the Sucess Rate of Percutaneous Transluminal Angioplasty?
Divison of Urology, Renal Transplantation Unit, University of São Paulo, São Paulo, SP, Brazil.
Purpose: The incidence of transplant renal artery stenosis (TRAS) ranges from 1 to 23% and is the most frequent vascular complication following renal transplantation. It…2015 American Transplant Congress
Longitudinal Multi-Omic Profiling of Genes and Pathways Underlying Cardiac Allograft Rejection
Our ability to treat cardiac allograft rejection in both acute and chronic states is typically limited by poor existing biomarkers to predict the occurrence of…2015 American Transplant Congress
Perturbation of Polyomavirus Nephropathy-Specific Gene Expression in Kidney Allografts
Polyomavirus nephropathy (PVAN) is a common cause of kidney allograft dysfunction and loss. Microscopic observations of PVAN are similar to T-cell mediated rejection (TCMR), with…2015 American Transplant Congress
Defining and Directing T Cell Subsets Involved in Rejection of Vascularized Composite Allografts
Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD.
Purpose: Wider utilization of VCA is hampered by the need for long-term immunosuppression. Barriers to more targeted immunosuppression in VCA include (1) limited knowledge of…2015 American Transplant Congress
Is Ex Vivo Liver Perfusion a Safe Alternative to Cold Static Storage for the Preservation of Standard Criteria Grafts?
Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.
Objective: Subnormothermic ex vivo liver perfusion (SNEVLP) has recently attracted great interest in the field of organ preservation for marginal grafts. However, data is lacking…2015 American Transplant Congress
The 20S Proteasome Is Active in Apoptotic Nanovesicles and Controls Anti-LG3 Antibody Production
Humoral autoreactivity to apoptotic cells and perlecan/LG3, a proteoglycan fragment released by apoptotic cells, predicts poor allograft outcomes in renal transplant patients. How apoptotic cells…2015 American Transplant Congress
Pancreas Transplant Sera Improves the Function and Proliferation of Endothelial Cells
Transplant Services, Allegheny General Hospital, Pittsburgh, PA.
Pancreas transplantation (Tx) allows for the study of diabetes by examining the reversal of the disease. Previously, we observed that after pancreas Tx many patients'…
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