ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Effector T Cell Migration to Pancreatic Islet Allografts Is Dependent On Donor Antigen Recognition and Not Gαi Chemokine Signaling

    Q. Zhang, H. Dai, Q. Zeng, A. Williams, M. Oberbarnscheidt, F. Lakkis.

    Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA.

    Infiltration of the graft with host effector T cells after transplantation is a key step in the pathogenesis of both acute and chronic rejection. Recent…
  • 2015 American Transplant Congress

    Pregnancy Outcomes in Female Kidney Transplant Recipients: Does Ethnicity Have an Influence?

    S. Constantinescu,1,2 L. Coscia,2 D. Armenti,2 P. Axelrod,1 M. Ghanta,1 S. Rao,1 M. Moritz.2,3

    1Temple University School of Medicine, Philadelphia; 2National Transplantation Pregnancy Registry, Gift of Life Institute, Philadelphia; 3Lehigh Valley Health Network, Allentown.

    The purpose of this study was to analyze pregnancy outcomes in female kidney transplant recipients by ethnicity. Data were collected by the National Transplantation Pregnancy…
  • 2015 American Transplant Congress

    Impact of Pretransplant Sarcopenia and Sequential Changes in Sarcopenic Parameters After Living Donor Liver Transplantation

    T. Kaido,1 Y. Tamai,2 K. Ogawa,1 Y. Fujimoto,1 A. Mori,1 H. Okajima,1 N. Inagaki,2 S. Uemoto.1

    1Hepato-Biliary-Pancreatic and Transplant Surgery, Kyoto University, Kyoto, Japan; 2Metabolism and Clinical Nutrition, Kyoto University Hospital, Kyoto, Japan.

    The present study investigated the impact of pretransplant sarcopenia on survival and sequential changes in sarcopenic parameters in patients undergoing living donor liver transplantation (LDLT).…
  • 2015 American Transplant Congress

    Multivisceral Transplantation Without an Ostomy – Experience With 15 Patients

    T. Beduschi, J. Garcia, S. Nishida, A. Tekin, J. Fan, G. Selvaggi, P. Ruiz, R. Vianna.

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.

    Introduction: Despite improvement in short term outcomes, rejection remains a main cause of graft and patient loss in intestinal transplant. A temporary ostomy to assess…
  • 2015 American Transplant Congress

    Small RNA Sequencing-Enabled Discovery of Circulating Extracellular MicroRNAs as Noninvasive Biomarkers of Liver Allograft Status

    H. Yang,1 T. Muthukumar,1 K. Akat,2 D. Briskin,2 T. Tuschl,2 M. Suthanthiran.1

    1Weill Cornell Medical Center, New York; 2Rockefeller University, New York.

    MicroRNAs are ideal candidates as blood-based biomarkers. Comprehensive profiling of microRNAs is challenging. We overcame the existing challenges by developing robust protocols for isolation of…
  • 2015 American Transplant Congress

    Patients With Severe and Morbid Obesity Benefit from Deceased Donor Kidney Transplant

    A. Nishio Lucar,1 J. Ma,2 G. Vranic,1 D. Keith.1

    1Medicine, University of Virginia, Charlottesville, VA; 2Biostatistics, University of Virginia, Charlottesville, VA.

    More than one in three Americans are obese yet obesity is considered a relative and sometimes absolute contraindication to kidney transplant. Previous studies suggest that…
  • 2015 American Transplant Congress

    Reasons for Match Offer Refusals and Efforts to Reduce Them in the OPTN/UNOS Kidney Paired Donation Pilot Program (KPDPP)

    R. Leishman,1 D. Stewart,1 A. Kucheryavaya,1 L. Robbins Callahan,1 T. Sandholm,2 M. Aeder.3

    1UNOS, Richmond, VA; 2Carnegie Mellon Univ, Pittsburgh, PA; 3Univ Hosp Case Med Ctr, Cleveland, OH.

    Background: The OPTN/UNOS KPDPP has been finding 2-way, 3-way, and chain exchanges since Oct 2010. Though the number of pairs entered, matches found, and transplants…
  • 2015 American Transplant Congress

    Changes in Acceptances Patterns Under Share 35

    K. Washburn, E. Edwards, A. Harper.

    University of Texas HSC, San Antonio, TX; UNOS, Richmond, VA.

    The Share 35 policy was implemented June 2013 with intent of directing to livers to the sickest patients with the highest mortality and presumably shortest…
  • 2015 American Transplant Congress

    Closing the Knowledge Gap: The Successful Launch of an Interactive Website Dedicated to Information on Living Kidney Donor Transplantation

    D. Slaats,1 W. Zuidema,1 J. van de Wetering,1 D. Hesselink,1 T. Terkivatan,2 M. Betjes.1

    1Internal Medicine, Division of Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands; 2Surgery, Division of Transplant Surgery, Erasmus MC, Rotterdam, Netherlands.

    Introduction. The internet is increasingly used to find reliable information about living kidney donation (LKD) and transplantation (LKT). Therefore, an easily accessible, interactive website was…
  • 2015 American Transplant Congress

    MicroRNA (miR) 144 Dysregulates TGFβ Signaling Cascade and Contributes to Development of BOS Following Human Lung Transplantation

    Z. Xu,1 S. Ramachandran,1 D. Nayak,1 M. Gunasekaran,1 E. Trulock,1 R. Hachem,1 D. Kreisel,1 T. Mohanakumar.1

    1Surgery, Washington Univ Sch Med, St. Louis, MO; 2Medicine, Washington Univ Sch Med, St. Louis, MO.

    Background: Bronchiolitis Obliterans Syndrome (BOS) is characterized by a fibroproliferative cascade that is not amenable to current treatment regimens and remains the major impediment for…
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