ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Predictive Value of Cardiovascular Risk Assessment Tools in Kidney Transplantation

    C. Dunn, A. Holtzman, M. Hung, S. Greenstein.

    Surgery, Albert Einstein College of Medicine, Bronx, NY.

    Cardiovascular disease is a major cause of morbidity and mortality following kidney transplantation. Many cardiovascular risk screening tools have been developed, but they have never…
  • 2015 American Transplant Congress

    Hyperuricemia Takes a Toll in Graft Function, Left Ventricular Diameters and Arterial Stiffness in Renal Transplant Recipients

    B. Gurlek Demirci,1 S. Sezer,1 C. Oygur,2 Z. Bal,1 E. Tutal,1 M. Haberal.3

    1Department of Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey; 2Department of Internal Medicine, Baskent University Faculty of Medicine, Ankara, Turkey; 3Department of General Surgery, Baskent University Faculty of Medicine, Ankara, Turkey.

    Purpose: Cardiovascular diseases are the leading cause of morbidity and mortality in renal transplant recipients (RTRs). Serum uric acid (UA) levels correlate with many recognized…
  • 2015 American Transplant Congress

    Efficacy and Safety of Once-Daily Everolimus With Minimized Once-Daily Tacrolimus After Liver Transplantation

    P. De Simone,1 P. Carrai,1 L. Coletti,1 A. Precisi,2 D. Campani,3 F. Filipponi.1

    1Hepatobiliary Surgery and Liver Transplantation, University of Pisa Medical School Hospital, Pisa, Italy; 2Laboratory, University of Pisa Medical School Hospital, Pisa, Italy; 3Pathology, University of Pisa Medical School Hospital, Pisa, Italy.

    Background: The everolimus (EVR) pharmacokinetic profile allows for its once daily (OD) administration. We tested the efficacy and safety of a combination schedule of OD-EVR…
  • 2015 American Transplant Congress

    The Best Regimen With Rituximab for ABO-Incompatible Living Donor Liver Transplantation

    H. Egawa,1 K. Umeshita,2 S. Uemoto.3

    1Surgery, Tokyo Women's Medical University, Tokyo, Japan; 2Osaka University, Suita, Japan; 3Kyoto University, Kyoto, Japan.

    Rituximab made a great progress on outcomes of ABO-incompatible living donor liver transplantation (ABO-I LDLT). Although Japanese multicenter study group published efficacy and safety of…
  • 2015 American Transplant Congress

    Treatment Patterns, Healthcare Resource Utilization, and Costs in Kidney Transplant Recipients Using a Fixed Source Regimen of Tacrolimus Vs. a Variable Source Regimen

    E. Lee,1 S. Bunniran,2 P. Kamble,2 B. Suehs,2 B. Franks,1 J. Schwartz,1 C. Anderson,3 G. Thal,1 J. Spalding.1

    1Astellas Scientific and Medical Affairs, Northbrook, IL; 2Comprehensive Health Insights, Humana, Louisville, KY; 3Humana, Louisville, KY.

    BackgroundTacrolimus (TAC) has evolved to be the foundation of kidney transplant immunosuppressant protocols. However, the implications of switching between multiple formulations of TAC have not…
  • 2015 American Transplant Congress

    Immunomodulation of Human T Cells by a Novel RALG Preparation With Higher Specificity Toward Activating T Cells

    K. Samy, H. Xu, A. Kirk.

    Surgery, Duke University Medical Center, Durham, NC.

    Current induction therapy using thymoglobulin (ATG) results in nonspecific T cell depletion. We have generated a polyclonal rabbit anti-human leukocyte globulin (RALG) by immunizing rabbits…
  • 2015 American Transplant Congress

    Thymic Transplantation to Determine Mechanisms of Thymic Involution: Insulin-Like Growth Factor 1 Receptor and Forkhead Box Protein N1 in the Thymus Play a Role in Maintaining the Juvenile Thymus

    K. Yamada, M. Tasaki, M. Sekijima, A. Kawai, V. Villani, T. Tanabe, I. Hanekamp, A. Shimizu, D. Sachs.

    Transplantation Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boton, MA.

    Thymic involution has long been associated with age-related changes of the immune system, although the cause remains unclear. We have extensively studied the role of…
  • 2015 American Transplant Congress

    Immunodeficiency Assessment in Pediatric Intestinal Failure Patients

    J. Garcia,1 T. Beduschi,1 C. Biaggi,2 E. Perez,2 A. Tekin,1 M. McGetrick,3 L. Cubley,1 P. Ruiz,1 J. Fan,1 S. Nishida,1 G. Selvaggi,1 R. Vianna.1

    1Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL; 2Pediatrics, University of Miami Miller School of Medicine, Miami, FL; 3University of Miami Miller School of Medicine, Miami, FL.

    Intestinal failure (IF) is a clinical condition for which intestinal transplantation may be indicated. Patients without enteral autonomy have an increased risk of malnutrition which…
  • 2015 American Transplant Congress

    Clinical and Immunologic Risk Factors Associated With Donor-Specific Antibody (DSA) Formation Following Renal Transplantation

    C. Johnson,1 S. Park,1 J. Schiller.2

    1Department of Surgery, Medical College of Wisconsin, Milwaukee, WI; 2Blood Center of Wisconsin, Milwaukee, WI.

    Background: De novo DSA formation is emerging as an important risk factor for adverse graft outcomes following renal transplantation. Specific pretransplant risk factors for DSA…
  • 2015 American Transplant Congress

    Evaluation of Medication Regimen Complexity Over Time Following Heart Re-Transplantation

    B. Bryant,1 A. Libby,1 R. Page,1 J. Lindenfeld,2 C. Aquilante.1

    1University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO; 2University of Colorado School of Medicine, Aurora, CO.

    Medication regimen complexity (MRC) includes many characteristics of a drug regimen. Previously, we showed that MRC is high and persists over time after primary heart…
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