ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Stable and Unstable Chimerism During Immunosuppressive Drug Withdrawal in Tolerant Recipients of HLA Matched Combined Kidney and Hematopoietic Cell Transplants

    T. Pham,1 S. Busque,1 J. Scandling,2 J. Shizuru,2 S. Asha,1 S. Strober.2

    1Surgery, Stanford University, Palo Alto, CA; 2Medicine, Stanford University, Palo Alto, CA.

    Our previous studies showed that 75-80% of HLA matched recipients of combined kidney and hematopoietic cell transplants conditioned with total lymphoid irradiation (TLI) and anti-thymocyte…
  • 2015 American Transplant Congress

    The Spleen Is the Primary Site for Breg Induction and Is Required for Anti-TIM-1 Mediated Tolerance

    K. Mohib, Q. Ding, A. Cherukuri, D. Rothstein.

    Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.

    B cells can exhibit potent IL-10-dependent regulatory (Breg) activity. IL-10-enriched Bregs can transfer tolerance in auto and allo-immune models. We showed that TIM-1 is an…
  • 2015 American Transplant Congress

    The Role of Hemodialysis Social Networks in Transplantation: Five Year Follow Up of an Urban Hemodialysis Cohort

    A. Pai, A. Gillespie.

    Nephrology, Hypertension, and Kidney Transplantation, Temple University, Philadelphia, PA.

    Background: Racial and socioeconomic disparities are well known barriers to kidney transplantation (KT), especially among minority populations. Emerging evidence suggests social networks exist within hemodialysis…
  • 2015 American Transplant Congress

    Impact of Induction Therapy on Outcomes in HIV + Renal Transplant Recipients

    C. Kershaw,1 C. Rogers,2,4 M. Pavlakis,1,2 H. Tang,2 C. Alonso,1,2 K. Khwaja,2,3 A. Evenson,2,3 K. Raven,2,3 M. Wong.1,2

    1Medicine, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA; 2The Transplant Institute, BIDMC, Boston, MA; 3Surgery, BIDMC, Boston, MA; 4Pharmacy, BIDMC, Boston, MA.

    Purpose: Kidney transplantation in HIV+ recipients has been complicated by higher than expected acute rejection rates (AR). Induction immunosuppression may or may not impact this…
  • 2015 American Transplant Congress

    Implications of Living Donor Kidney Histology, Volume and Function on Post-Donation GFR

    Z. Zaky,1 B. Lankowsky,2 S. Shah,1 L. Herlitz,1 A. Chiesa-Vottero,1 K. Wallenfelsz,1 A. Caplin,1 D. Goldfarb,1 S. Flechner,1 J. Schold,1 E. Poggio.1

    1Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH; 2CWRU School of Medicine, Cleveland, OH.

    Living kidney donor transplantation is the best modality for treating ESRD as it confers excellent outcomes to patients and it is safe for donors. Postdonation…
  • 2015 American Transplant Congress

    Multicenter Study to Develop a Novel Prediction Index for Hepatocellular Carcinoma (HCC) Recurrence After Liver Transplant (LT)

    N. Mehta,1 J. Heimbach,2 D. Harnois,3 J. Dodge,1 J. Burns,3 D. Lee,3 W. Sanchez,2 J. Roberts,1 F. Yao.1

    1UCSF, San Francisco, CA; 2Mayo Clinic, Rochester, MN; 3Mayo Clinic, Jacksonville, FL.

    Several factors have been associated with a high risk of recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT), but no reliable risk score has…
  • 2015 American Transplant Congress

    Comparison of Efficacy of Prophylactic Antivirus Therapies on Outcomes of Kidney Transplantation in Hepatitis B Virus Carriers

    G. Chen, C. Wang, J. Qiu, J. Li, L. Chen.

    Organ Transplant Center, The first affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Purpose To compare the efficacy between entecavir and lamivudine as prophylactic antivirus therapy on long-term outcomes of HBV carriers after kidney transplantation.Methods We retrospectively reviewed…
  • 2015 American Transplant Congress

    Increasing the Number of Organ Transplants in the United States by Optimizing Donor Authorization Rates

    D. Goldberg,1 B. French,2 P. Abt,3 R. Gilroy.4

    1Department of Medicine, University of Pennsylvania, Philadelphia, PA; 2Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA; 3Department of Surgery, University of Pennsylvania, Philadelphia, PA; 4Department of Medicine, University of Kansas Medical Center, Kansas City, KS.

    Introduction: The highest priority in the Organ Procurement and Transplantation Network (OPTN) Strategic Plan is to increase the number of transplants among patients with end-stage…
  • 2015 American Transplant Congress

    Pancreas-Derived Mesenchymal Stem Cells from Chronic Pancreatitis Patients Enhance Islet Graft Function

    M. Lawrence,1 F. Kunnathodi,1 N. Borenstein-Auerbach,1 G. Yoshimatsu,1 M. Kanak,2 R. Shahbazov,1 M. Takita,1 M. Levy,3 B. Naziruddin.3

    1Baylor Research Institute, Dallas, TX; 2Baylor University, Waco, TX; 3Baylor Annette C. and Harold C. Simmons Transplant Institute, Dallas, TX.

    PURPOSE: Islet transplantation represents a promising procedure to reverse or prevent diabetes. However, significant mass of islet graft is lost within hours of transplantation due…
  • 2015 American Transplant Congress

    Effect of Everolimus on Left Ventricular Hypertrophy in De Novo Kidney Transplant Recipients: 12-Month Results from the ELEVATE Study

    M. van der Giet,1 H. Holdaas,1 J. de Fijter,1 A. Speziale,2 C. Escrig,2 G. Junge,2 Z. Wang,3 J. Cruzado.1

    1For the ELEVATE Study, Berlin, Germany; 2Novartis, Basel, Switzerland; 3Novartis Corporation, East Hannover, NJ.

    Background: Left ventricular hypertrophy (LVH) is common in kidney transplant recipients (KTxR) and has shown to be a risk factor for death and heart failure…
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