2015 American Transplant Congress
Focal Segmental Glomerulosclerosis Recurrence in Renal Transplant Recipients Treated With Belatacept
Introduction: Focal segmental glomerulosclerosis (FSGS) is a cause of end-stage renal failure that frequently recurs following renal transplant, often leading to early allograft loss. A…2015 American Transplant Congress
Virus Induced CD28 Down-Regulation as a Potential Driver of Costimulation Blockade Resistant Rejection
1Surgery, Emory University, Atlanta, GA; 2Surgery, Duke University, Durham, NC.
Belatacept, a B7-specific fusion protein, blocks CD28-B7 costimulation and prevents kidney allograft rejection. However, it is ineffective in a sizable minority of patients. Although T…2015 American Transplant Congress
Norovirus Infection in Renal Transplant Recipients – Clinical Severity and Genotype Identification
Introduction: Norovirus (NoV) is increasingly recognized as causative agent of gastro-enteritis in renal transplant recipients.Methods: We performed a retrospective study (2003-2012) to investigate the clinical…2015 American Transplant Congress
Dramatic Improvements in Racial Disparities in Kidney Transplant Outcomes in the US
1Johns Hopkins, Baltimore; 2Duke University, Durham.
Earlier studies reported inferior graft survival in black transplant recipients. We examined 20-year trends in outcomes to determine whether racial disparities improved over time. METHODS:…2015 American Transplant Congress
Effector T Cell Migration to Pancreatic Islet Allografts Is Dependent On Donor Antigen Recognition and Not Gαi Chemokine Signaling
Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA.
Infiltration of the graft with host effector T cells after transplantation is a key step in the pathogenesis of both acute and chronic rejection. Recent…2015 American Transplant Congress
Pregnancy Outcomes in Female Kidney Transplant Recipients: Does Ethnicity Have an Influence?
The purpose of this study was to analyze pregnancy outcomes in female kidney transplant recipients by ethnicity. Data were collected by the National Transplantation Pregnancy…2015 American Transplant Congress
Impact of Pretransplant Sarcopenia and Sequential Changes in Sarcopenic Parameters After Living Donor Liver Transplantation
The present study investigated the impact of pretransplant sarcopenia on survival and sequential changes in sarcopenic parameters in patients undergoing living donor liver transplantation (LDLT).…2015 American Transplant Congress
Multivisceral Transplantation Without an Ostomy – Experience With 15 Patients
Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.
Introduction: Despite improvement in short term outcomes, rejection remains a main cause of graft and patient loss in intestinal transplant. A temporary ostomy to assess…2015 American Transplant Congress
Blood Gene Expression Profiling in a Randomized Controlled Trial of rATG Vs. IL2RA Induction Reveals the Differences in Immune Impact and Mechanisms
1MUSC, Charleston, SC; 2Scripps Research Institute, La Jolla, CA.
We performed global gene expression profiling using microarrays on samples from a prospective, RCT designed to study the safety & efficacy of induction with antithymocyte…2015 American Transplant Congress
Associations of Pre-Transplant Prescription Narcotic Use With Clinical Complications After Kidney Transplantation
Background: Associations of narcotic use before kidney transplantation with post-transplant clinical outcomes are not well described.Methods: We performed a retrospective analysis of linked national registry…
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