ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Arterial Blood Pressure at Time of Liver Transplant (LT) Evaluation Correlates With Kidney Biopsy Findings in LT Candidates With Renal Dysfunction

    H. Wadei, A. Peguero, A. Alsaad, M. Mai, K. Oshel, T. Gonwa, C. Taner, A. Keaveny.

    Transplant, Mayo Clinic, Jacksonville, FL.

    Renal dysfunction is common in LT candidates; however, predicting post-LT renal recovery is sometimes difficult. Kidney biopsy is helpful in identifying reversible renal injury but…
  • 2015 American Transplant Congress

    Examining Long-Term Survivors in Combined Heart-Lung Transplantation

    S. Kadakia,1 S. Jayarajan,1 S. Taghavi,1 V. Ambur,1 C. Lewis,1 A. Shiose,2 G. Wheatley III,2 L. Kaiser,3 T. Guy,2 Y. Toyoda.2

    1Department of Surgery, Temple University Hospital, Philadelphia, PA; 2Division of Cardiovascular Surgery, Temple University Hospital, Philadelphia, PA; 3Division of Thoracic Surgery, Temple University Hospital, Philadelphia, PA.

    The goal of this study was to determine variables associated with mortality in combined heart-lung transplantation (HLT).The United Network for Organ Sharing (UNOS) database was…
  • 2015 American Transplant Congress

    Defining the Epidemiologic Landscape of HIV-Infected Deceased Donors in the United States

    A. Cash, A. Shaffer, S. Anjum, A. Massie, D. Segev, C. Durand.

    Surgery, Johns Hopkins University, Baltimore, MD.

    The HIV Organ Policy Equity Act mandates research on the use of HIV-infected (HIV+) deceased donors (HIVDD) for transplantation in HIV+ recipients. The only data…
  • 2015 American Transplant Congress

    Transplanting Pediatric Livers Into Adult Recipients Is Associated With Increased Rejection and Decreased Survival

    V. Fleetwood, J. Harris, M. Hertl, E. Chan.

    General Surgery, Division of Transplantation, Rush University Medical Center, Chicago, IL.

    Introduction: Transplantation of pediatric livers to adult recipients, a measure which places the graft at higher risk of hepatic artery thrombosis (HA), is frequently necessitated…
  • 2015 American Transplant Congress

    The Impact of High-Risk Lung Donors on the Survival of Lung Recipients With Interstitial Pulmonary Fibrosis

    P. Sanchez,1 M. Mulligan,1 C. Evans,1 I. Timofte,2 J. Kim,2 K. Rajagopal,1 A. Iacono,2 J. Gammie,1 R. Pierson III,1 B. Griffith,1 S. Pham.1

    1Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD; 2Medicine, University of Maryland School of Medicine, Baltimore, MD.

    Matching donors and recipients is largely based on experience. With the implementation of the LAS, IPF candidates have the highest provability of being transplanted after…
  • 2015 American Transplant Congress

    In Vivo Expansion of Donor-Specific Regulatory T Cells by a New Triazolopyrimidine Derivative and Donor-Specific Transfusion

    S. Emoto,1 R. Goto,1 S. Shibasaki,1 A. Nagatsu,1 H. Ono,1 R. Igarashi,1 M. Fukai,2 T. Shimamura,3 K. Saiga,4 M. Murakami,5 A. Taketomi,1 S. Todo,6 K. Yamashita.2

    1Gastroenterological Surgery 1, Hokkaido University, Sapporo, Japan; 2Transplant Surgery, Hokkaido University, Sapporo, Japan; 3Division of Organ Transplantation, Hokkaido University Hospital, Sapporo, Japan; 4Nippon Kayaku, Tokyo, Japan; 5Institute for Genetic Medecine, Hokkaido University, Sapporo, Japan; 6Research Institute, St. Mary Hospital, Kurume, Japan.

    Background: We have previously demonstrated that a new triazolopyrimidine derivative, NK026680 (NK) prevents activation/maturation of dendritic cells. This study investigated whether NK together with donor-specific…
  • 2015 American Transplant Congress

    CHBP Suppresses Acute Rejection by Inhibition Maturation of Dendritic Cells though Jak-2/STAT3/SOCS1 Signal in Rat Kidney Transplantation

    C. Yang,1 Y. Zhang,1 J. Wang,1 L. Li,1 L. Wang,2 M. Xu,1 Y. Long,3 R. Rong,1 T. Zhu.1

    1Urology, Zhongshan Hospital, Fudan University, Shanghai, China; 2Biomedical Research Center, Zhongshan Hospital, Fudan University, Shanghai, China; 3CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

    Background. Renal acute rejection (AR) affects both allografts and recipients survival. We recently synthesized a novel proteolysis-resistant cyclic helix B peptide (CHBP), which exerts promising…
  • 2015 American Transplant Congress

    Molecular Correlates of Endothelial mTOR Activation in Heart Transplants Recipients

    M. Racape, A. Loupy, J. Reeve, J. Venner, R. Guillemain, L. Hidalgo, C. Lefaucheur, X. Jouven, P. Bruneval, P. Halloran, J. Duong.

    Paris Transplant Group & ATAGC, Paris - Edmonton, France.

    BackgroundThe detection of phosphorylated effectors of the mTOR pathway in endothelial cells has been associated with in allograft rejection in animal models. The aim of…
  • 2015 American Transplant Congress

    Intra-Renal Cytokine Measurement Detected During Kidney Allograft Biopsies Portend Severity of Histological Injury

    N. Leca, S. Anderson, K. Muczynski.

    Division of Nephrology, University of Washington, Seattle, WA.

    Histological changes observed on renal allograft biopsies, although considered the current standard for evaluation of allograft injury, lack specificity and disease activity assessment. We devised…
  • 2015 American Transplant Congress

    Predicting and Preventing 30-Day Readmission Following Kidney Transplantation: A Single Center Study

    R. Khaim,1 V. Nair.1,2

    1Recanati Miller Transplant Institute, The Mount Sinai Hospital, NY, NY; 2Medicine, Icahn School of Medicine at Mount Sinai, NY, NY.

    Purpose: Readmissions are a major morbidity following kidney transplantation (KT). Prior studies report a 30-day readmission rate of 30%. Limited data exist on risk facotors…
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