Am J Transplant, Volume 5, Suppl 3 Archives - Page 30 of 170 - ATC Abstracts

2015 American Transplant Congress
Combined Anti-IL6R and CTLA4Ig Therapy Attenuates Recall Alloantibody Responses in a Mouse Model of HLA Sensitization
N.-N. Chai, G. Wu, I. Kim, A. Klein, S. Jordan.
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
[bald]Background[/bald] We previously reported that IL-6 inhibition by anti-IL6R antibody (mMR16-1) or CD28 pathway inhibition using CTLA4Ig (abatacept) reduced recall alloantibody responses in a mouse…
2015 American Transplant Congress
Frailty in Patients Being Evaluated for Kidney Transplantation
M. McAdams DeMarco, I. Olorundare, N. Desai, N. Dagher, B. Lonze, R. Montgomery, D. Segev.
Johns Hopkins, Baltimore.
BACKGROUND: In patients undergoing hemodialysis, frailty prevalence is high and predicts mortality and hospitalization. Little is known about frailty in patients with ESRD who are…
2015 American Transplant Congress
Long-Term Outcomes of Transplantation Using Kidneys from Expanded Criteria Donors
O. Aubert,¹ Kamar,² Vernerey,¹ Viglietti,¹ Duong van Huyen,¹ Rabant,¹ Rostaing,² Congy,² Guilbeau-Frugier,² Martinez,¹ Delahousse,¹ Glotz,¹ Jouven,¹ Legendre,¹ Lefaucheur,¹ Loupy.¹
¹Paris Translational Research Center for organ Transplantation, Paris, France; ²Department of Nephrology and Organ Transplantation, CHU Rangueil, Toulouse, France.
BackgroundSince the initial definition of ECD established in 2002, their use worldwide has evolved unequally, resulting in a high discard rate. A better understanding of…
2015 American Transplant Congress
Opportunities in Tacrolimus Therapeutic Drug Monitoring
N. Jandovitz, J. Lee, S. Hammad, J. McKeen, S. Martin, D. Tsapepas.
Department of Pharmacy, NewYork-Presbyterian Hospital, NY.
Tacrolimus requires diligent therapeutic drug monitoring (TDM) to maintain appropriate serum concentrations after transplant. To optimize efficacy & minimize toxicity frequent levels are drawn, commonly…
2015 American Transplant Congress
Risk Factors for Infections After Transplant in a Prospective Cohort Study Including Incompatible Kidney Transplant Recipients
R. Avery,¹ H.-L. Tsai,² C.-Y. Huang,² S. Shoham,¹ D. Ostrander,¹ N. Lu,¹ R. Montgomery,³ K. Marr.¹
¹Infectious Disease, Johns Hopkins, Baltimore, MD; ²Biostatistics and Bioinformatics, Johns Hopkins, Baltimore, MD; ³Transplant Surgery, Johns Hopkins, Baltimore, MD.
Background: Infectious morbidity is a cumulative function of recurrent events. Historically, data collection has depended on time-to-event analyses, variable definitions, and retrospective data. To better…
2015 American Transplant Congress
Desensitization Before Living Donor Kidney Transplantation in Highly Sensitized Patients
E. De Sousa,¹ I. Revuelta,¹ M. Blasco,¹ F. Diekmann,¹ J. Cid,² M. Lozano,² A. Sánchez-Escuredo,¹ J. Martorell,³ E. Palou,³ J. Campistol,¹ F. Oppenheimer.¹
¹Nephrology, Hospital Clinic Barcelona, Barcelona, Spain; ²Hemotherapy and Hemostasis, Hospital Clinic Barcelona, Barcelona, Spain; ³Immunology, Hospital Clinic Barcelona, Barcelona, Spain.
Renal transplantation in highly sensitized patients represents a major clinical challenge leading to long periods in the waiting list. When a living donor is available,…
2015 American Transplant Congress
In House Oxygen Persufflation of Cold Stored Livers Versus Simple Cold Storage in Extended Criteria Liver Grafts: Results of a Randomized Controlled Clinical Trial
A. Gallinat,¹ A. Paul,¹ D. Hoyer,¹ C. Klein,¹ S. Swoboda,¹ C. Ose,² Z. Mathe,¹ J. Treckmann,¹ T. Minor.³
¹Dept. of General-, Viszeral- und Transplantation Surgery, University Hospital Essen, Essen, Germany; ²Institute of Computer Science in Medicine, Biostatistics and Epidemiology, University Hospital Essen, Essen, Germany; ³Surgical Research Div., Universiy Clinic Surgery, Bonn, Germany.
Two hours of end-ischemic oxygen persufflation of cold stored porcine livers regenerates cellular energy dependent pathways and improves survival after transplantation. The present trial evaluated…
2015 American Transplant Congress
U.S. National Experience of Liver Transplantation Using Allografts from Octogenarian Donors
C. Bhati, I. Tzvetanov, R. Garcia-Roca, J. Oberholzer, E. Benedetti, H. Jeon.
Surgery, Division of Transplantation, University of Illinois at Chicago, Chicago, IL.
IntroductionA continuous worsening of donor organ shortage has led to expand organ acceptance criteria. It is still theoretically possible to utilize hepatic allografts from donors…
2015 American Transplant Congress
A Novel Tool to Evaluate Coercion, Pressure, and Motivation in Potential Live Kidney Donors
A. Shaffer,¹ E. King,¹ J. Kahn,² L. Erby,³ D. Segev.¹
¹Surgery, Johns Hopkins University, Baltimore, MD; ²Bergman Institute for Bioethics, Johns Hopkins University, Baltimore, MD; ³School of Public Health, Johns Hopkins University, Baltimore, MD.
Live donor kidney transplantation yields improved graft survival and recipient longevity, as compared to deceased donors. However, one concern with living donation is the potential…
2015 American Transplant Congress
Addressing Low Live Kidney Donation Rates in African Americans through the Live Donor Champion Program
E. King,¹ J. Garonzik-Wang,³ M. Bowring,¹ K. Kumar,¹ D. Segev.^1,2
¹Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD; ²Epidemiology, Johns Hopkins University, School of Public Health, Baltimore, MD; ³Transplantation, Washington University, School of Medicine, St. Louis, MO.
Background: African-Americans (AAs) are least likely to receive a live donor kidney transplant, and AAs account for < 20% of all live donors. Differences in…