ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    A Novel Tool to Evaluate Coercion, Pressure, and Motivation in Potential Live Kidney Donors

    A. Shaffer,1 E. King,1 J. Kahn,2 L. Erby,3 D. Segev.1

    1Surgery, Johns Hopkins University, Baltimore, MD; 2Bergman Institute for Bioethics, Johns Hopkins University, Baltimore, MD; 3School of Public Health, Johns Hopkins University, Baltimore, MD.

    Live donor kidney transplantation yields improved graft survival and recipient longevity, as compared to deceased donors. However, one concern with living donation is the potential…
  • 2015 American Transplant Congress

    Addressing Low Live Kidney Donation Rates in African Americans through the Live Donor Champion Program

    E. King,1 J. Garonzik-Wang,3 M. Bowring,1 K. Kumar,1 D. Segev.1,2

    1Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD; 2Epidemiology, Johns Hopkins University, School of Public Health, Baltimore, MD; 3Transplantation, Washington University, School of Medicine, St. Louis, MO.

    Background: African-Americans (AAs) are least likely to receive a live donor kidney transplant, and AAs account for < 20% of all live donors. Differences in…
  • 2015 American Transplant Congress

    The Impact of Perioperative Bleeding on Long-Term Outcomes of Mechanical Circulatory Support

    K. Lietz,1 M. Mooney,1 I. El Lakkis,2 C. Derber,2 U. Kelly,2 C. Wilson,2 A. Hoedt,1 P. Bourassa,1 B. Smith,1 M. McGrath,1 J. Herre.1

    1Sentara Norfolk General Hospital, Norfolk, VA; 2Eastern Virginia Medical School, Norfolk, VA.

    Purpose: Postoperative bleeding is a common complication of MCS surgery. The incidence of bleeding in published series exceeds by several times the 3-5% rates seen…
  • 2015 American Transplant Congress

    Safety and Efficacy of Conversion from Conventional Twice Daily Tacrolimus to Once Daily Extended Release Tacrolimus in Stable Pancreas Transplant (SPK and PAK) Recipients

    M. Dib, A. Barbas, M. Marquez, J. Laurence, G. Sapisochin, A. Norgate, J. Schiff, I. McGilvray, P. Greig, M. Selzner, M. Cattral.

    Surgery, Multi-Organ Transplant, Toronto General Hospital, Toronto, ON, Canada.

    Background: A once-daily, modified-release oral formulation of tacrolimus has been developed to simplify dosing and improve medication adherence. There is limited data on the implementation…
  • 2015 American Transplant Congress

    Comparison of Creatinine Based Estimated Glomerular Filtration Rate (eGFR) and Iothalamate-Measured GFR (mGFR) Following Simultaneous Pancreas – Kidney Transplantation

    N. Sarabu, J. Augustine, K. Woodside, D. Hricik, A. Padiyar, E. Sanchez.

    University Hospitals Case Medical Center, Cleveland.

    Objective: Creatinine based eGFR equations may overestimate the true GFR in simulataneous pancreas-kidney (SPK) transplant patients, owing to the low lean body mass in these…
  • 2015 American Transplant Congress

    Right-Sided Kidney Transplants Are Associated With Early Graft Failure in the Setting of Delayed Graft Function

    I. Hall, W. Jiang, S. Kulkarni, C. Parkih.

    Yale University, New Haven, CT.

    Anatomical differences between right and left kidneys may affect transplant outcomes. We sought to determine if the right kidney (RK) tends to have worse graft…
  • 2015 American Transplant Congress

    A Primary Cytomegalovirus Infection Post-Transplantation Has a Significant Impact on Circulating T Cells and Renal Allograft Function

    R. Meijers,1 N. Litjes,1 A. Langerak,2 C. Baan,1 M. Betjes.1

    1Internal Medicine section Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands; 2Immunology, Erasmus MC, Rotterdam, Netherlands.

    Study's purpose: Cytomegalovirus (CMV)-infection may profoundly affect the peripheral T-cell compartment and is associated with T-cell ageing and generation of cytotoxic CD4+CD28null T cells. We…
  • 2015 American Transplant Congress

    Elderly ESRD Patients Have a Significantly Narrowed T-Cell Receptor Repertoire Diversity

    L. Huang,1 A. Langerak,2 I. Wolvers - Tettero,2 R. Meijers,1 C. Baan,1 N. Litjens,1 M. Betjes.1

    1Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands; 2Immunology, Erasmus Medical Center, Rotterdam, Netherlands.

    IntroductionA diverse T-cell receptor (TCR) repertoire is central to effective T-cell mediated immune responses to foreign antigens. Patients suffering from end stage renal disease (ESRD)…
  • 2015 American Transplant Congress

    CD8 T Cell Biomarkers Improves the Capacities of the Kidney Transplant Failure Score for the Long-Term Prognostic of Kidney Graft Failures

    N. Degauque,1,2 M. Yap,1 G. Tilly,1,3 P. Guerrif,2 M. Giral,2 S. Brouard,1,2 Y. Foucher.2,3

    1INSERM UMR1064, Nantes, France; 2CHU de Nantes, Nantes, France; 3University of Nantes, Nantes, France.

    Background. Kidney transplantation is acknowledged as the treatment of choice for patients in end-stage renal disease compared to dialysis. We hypothesized that the efficiency of…
  • 2015 American Transplant Congress

    Operational Tolerance in Kidney Transplantation: Results of a Europe-Wide Survey

    A. Massart,1 A. Pallier,2 O. Viklicky,3,4 J. Pascual,3,5 K. Budde,3,6 S. Sorensen,3,7 R. Oberbauer,3,8 M. Klinger,3,9 C. Dudley,3,10 M. Sever,3,11 G. Spasovski,3,13 P. Guérif,2 U. Maggiore,3,12 M. Abramowicz,1 M. Giral,2 D. Abramowicz,14 S. Brouard.2

    1Erasme, Brussels, Belgium; 2Nantes University, Nantes, France; 3ERA-EDTA-DESCARTES Working Group, Parma, Italy; 4IKEM, Prague, Czech Republic; 5Hospital del Mar, Barcelona, Spain; 6CCM, Berlin, Germany; 7Rigshospitalet, Copenhagen, Denmark; 8KH Elisabethinen, Linz, Austria; 9WMU, Wrocław, Poland; 10NBT, Bristol, United Kingdom; 11IMSSC, Istanbul, Turkey; 12Ospedale Maggiore, Parma, Italy; 13UCC, Skopje, Macedonia, The Former Yugoslav Republic of; 14UZA, Antwerpen, Belgium.

    BACKGROUND: Operational Tolerance (opTOL) is deemed to be extremely rare in kidney transplantation. We launched a Europe-wide survey to assess the frequency of opTOL.METHODS: 18…
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