ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Immunological Characterization of Full Facial Transplant Recipients

    T. Borges,1 J. Azzi,1 S. Tullius,1 A. Chandraker,1 B. Pomahac,2 N. Najafian,1 L. Riella.1

    1Transplant Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston; 2Plastic Surgery, Boston.

    Background: Despite the skin being considered the most immunogenic of all human tissues, full facial transplantation (FFT) has become a life transforming procedure with encouraging…
  • 2015 American Transplant Congress

    Pre-Transplant Angiotensin Receptor II Type 1 Antibodies (AT1R) and Serum Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) as Predictors of Post Transpalnt FSGS Recurrence

    A. Khalil, T. Tim, A. Sharfuddin, S. Doshi, M. Yaqub, D. Mishler, W. Goggins, M. Mujtaba.

    Indiana University school of Medicine-IU Health Transplant, Indianapolis, IN.

    Approximately 30% of renal transplant patients develop recurrence of FSGS in the first kidney allograft. AT1R is expressed on podocytes; its expression is elevated in…
  • 2015 American Transplant Congress

    Improved Long-Term Graft Survival in Renal Transplant Recipients With Donor Specific Antibodies (DSA) After Mycophenolic Acid Escalation

    L. Rebellato,1 K. Parker,2 F. Rana,3 S. Kendrick,4 C. Morgan,5 C. Haisch,5 M. Everly,6 R. Harland,5 P. Bolin.3

    1Pathology and Laboratory Medicine, East Carolina University, Brody School of Medicine, Greenville, NC; 2Vidant Medical Center, Greenville, NC; 3Internal Medicine, East Carolina University, Brody School of Medicine, Greenville, NC; 4Eastern Nephrology Associates, Greenville, NC; 5Surgical Immunology and Transplantation, East Carolina University, Brody School of Medicine, Greenville, NC; 6Terasaki Foundation, Los Angeles, CA.

    Background: DSA formation in post-renal transplant patients is associated with chronic rejection and graft failure. Previous studies in our population indicate DSA formation is a…
  • 2015 American Transplant Congress

    Detecting Bowel Cancer in Pre-Dialysis, Dialysis Patients and Kidney Transplant Recipients – The DETECT Study

    G. Wong, J. Chapman, J. Craig.

    University of Sydney, Sydney, NSW, Australia.

    Background: Colorectal cancer (CRC) is the third most common solid organ cancer in people living with kidney disease, and has a very poor prognosis, with…
  • 2015 American Transplant Congress

    Clinical and Virologic Outcomes in High-Risk Adult EBV D+/R- Organ Transplant Recipients

    D. Kumar, N. Patil, S. Husain, C. Chaparro, A. Humar.

    UHN, Toronto, Canada.

    Background:EBV D+/R- organ transplant recipients are a high risk group for developing PTLD. This subgroup of patients has been primarily evaluated in pediatric populations with…
  • 2015 American Transplant Congress

    Rat dnIKK2-Treg Derived Exosomes Suppress T Cell Proliferation, Generate T Regulatory Cells and Prolong Kidney Allograft Survival

    S. Aiello, F. Rocchetta, N. Azzollini, S. Tomasoni, G. Remuzzi, M. Noris, A. Benigni.

    Istituto di Ricerche Farmacologiche Mario Negri, Ranica, Italy.

    Rat DCs, made immature by adenoviral gene transfer of dnIKK2, generated in MLR a unique population of CD4+ T regulatory cells (dnIKK2-Treg) which potently inhibited…
  • 2015 American Transplant Congress

    Influence of Race on P-Glycoprotein Function in Peripheral Blood Mononuclear Cells

    K. Tornatore,1 H. Minderman,2 K. O'Loughlin,2 K. Attwood,3 D. Brazeau,4 R. Venuto.5

    1NYS Center of Excellence in Bioinformatics & Life Science, School of Pharmacy, Buffalo; 2Flow Cytometry Laboratories, Roswell Park Cancer Institute, Buffalo; 3Biostatistics, School of Public Health, Buffalo; 4University of New England; School of Pharmacy, Portland, ME; 5Medicine, School of Medicine; University at Buffalo, Buffalo, NY.

    Purpose: African Americans (AA) renal transplant recipients (RTR) have poorer long term allograft survival compared to Caucasians(C) which may be attributed to racial differences in…
  • 2015 American Transplant Congress

    The Occurrence of v- Lesions Is Not Associated With Decreased Graft Survival

    P. Halloran, I. Salazar, M. Lopez, J. Chang.

    ATAGC, Edmonton, Canada.

    Intimal arteritis (v-lesions) in kidney transplant biopsies has been believed to have major prognostic and diagnostic significance. We assessed the relationship of v-lesions to prognosis…
  • 2015 American Transplant Congress

    A Prospective Comparison of the Completeness of Donor Kidney Biopsies

    S. Ahmad,1 E. Siskind,1 C. Drachenberg,2 J. Bromberg,1 S. Niederhaus.1

    1Transplantation, University of Maryland, Baltimore; 2Pathology, University of Maryland, Baltimore.

    Background: The use of expanded criteria kidneys has plateaued, possibly due to inadequate pathologic evaluation or lack of a universal grading system. We examined pre-transplant…
  • 2015 American Transplant Congress

    Geographic Variation in Listing Practices Represents Competetive Behaviors and Access to Care Rather Than Differences in Demand for Liver Transplantation

    J. Voss,1 R. Gilroy,1 D. Goldberg,2 T. Schmitt,1 S. Kumer.1

    1University of Kansas Medical Center, Kansas City, KS; 2University of Pennsylvania, Philadelphia, PA.

    Purpose: This study evaluates whether program and patient demographics influence liver transplant listing practices.Methods:2013 liver waiting list and transplant (Tx) variables, US Census socioeconomic variables,…
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