ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Pharmacoepidemiology of Cytomegalovirus Prophylaxis in a Large Multicenter Cohort of Kidney Transplant Recipients

    C. Santos, D. Brennan, V. Fraser, M. Olsen.

    Washington University School of Medicine, Saint Louis, MO.

    Background: Cytomegalovirus (CMV) prophylaxis or preemptive treatment are recommended for seronegative recipients of kidneys from seropositive donors (D+/R-) and seropositive patients (R+), but not D-/R-…
  • 2015 American Transplant Congress

    Identifying Predictors of Organ Donation Among African-American Men

    C. Harris,1 C. Modlin,1 S. Olden,2 A. Nowacki,3 T. Franklin,4 J. Canedy,1 M. Tavaras,1 A. Harris,1 Y. Hamilton,5 C. Zaramo.1

    1Glickman Urologic & Kidney Institute Minority Men's Health Center, Cleveland Clinic, Cleveland, OH; 2School of Medicine, Case Western Reserve University, Cleveland, OH; 3Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH; 4College of Medicine, Xavier University, New Orleans, LA; 5Lifebanc of Ohio, Cleveland, OH.

    Objective: The growth of the national transplant waiting list continues to far outpace the number of available organs, particularly among African Americans (AA). This study…
  • 2015 American Transplant Congress

    A Non-Haematopoietic Erythropoietin Analogue, ARA 290, Inhibits Macrophage Activation and Prevents the Transplanted Islet Graft Damage

    M. Watanabe,1 T. Lundgren,1 Y. Saito,1 A. Cerami,2 M. Brines,2 C.-G. östenson,3 M. Kumagai-Braesch.1

    1Division of Transplantation Surgery, Karolinska Institutet, Stockholm, Sweden; 2Araim Pharmaceuticals, Tarrytown, NY; 3Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

    Purpose. Pancreatic islet transplantation (PITx) is an attractive treatment option for type 1 diabetes patients. While pancreatic islets can successfully engraft after PITx a large…
  • 2015 American Transplant Congress

    A Prospective and Randomized Study of Conversion from Tacrolimus to Cyclosporine A to Improve Glucose Metabolism in Patients With New-Onset Diabetes Mellitus After Renal Transplantation

    K. Wissing,1 D. Abramowicz,2 L. Weekers,3 K. Budde,4 T. Rath,5 O. Witzke,6 D. Kuypers.7

    1Universitair Ziekenhuis Brussel, Brussels, Belgium; 2Universitair Ziekenhuis Antwerpen, Antwerpen, Belgium; 3Centre Hospitalier Universitaire Liège, Liège, Belgium; 4Charité Universitätsmedizin Berlin, Berlin, Germany; 5Westpfalz Klinikum Kaiserslautern, Kaiserslautern, Germany; 6Universitätsklinikum Essen, Essen, Germany; 7Universitair Ziekenhuis Leuven, Leuven, Belgium.

    Background: The present prospective and randomized study was designed to assess whether conversion from tacrolimus (Tac) to cyclosporine A (CsA) can reverse posttransplantation diabetes mellitus…
  • 2015 American Transplant Congress

    Impact of Anatomic Variation and Reconstructive Technique on Complications Following Living Liver Donor Transplantation – A Report from the A2ALL Consortium

    T. Baker,1 M. Zimmerman,2 B. Samstein,3 E. Pomfret,4 J. Pomposelli,4 C. Berg,5 N. Goodrich,6 B. Gillespie,7 J. Emond.3

    1Northwestern University, Chicago; 2University of Colorado, Denver; 3Columbia University, New York; 4Lahey Clinic, Burlington; 5Duke University, Durham; 6Arbor Research, Ann Arbor; 7University of Michigan, Ann Arbor.

    Introduction: Living donor liver transplantation [LDLT] is a technically demanding endeavor that requires command of the complex anatomy of partial liver grafts. The aim of…
  • 2015 American Transplant Congress

    Incidence, Timing, and Consequence of De Novo Donor Specific Antibody in Intestinal Transplantation

    C. Matsumoto, J. Hawksworth, S. Kozlowski, S. Rosen-Bronsen, A. Kromer, M. Grafals, N. Yazgi, S. Kaufman, K. Khan, R. Girlanda, E. Island, C. Desai, T. Fishbein.

    Center for Intestinal Care and Transplant, Medstar Georgetown Transplant Institute, Washington, DC.

    The development of denovo Donor specific antibody (dnDSA) in intestinal transplantation (ITx) remains largely unknown. We conducted a prospective and longitudinal analysis of adult and…
  • 2015 American Transplant Congress

    T Cell Receptor Repertoire Analysis of BKV-Specific T Cells in Peripheral Blood Samples By Next Generation Sequencing Reveals Differential Role and Kinetics of CD4 and CD8 T Cell Clones in Viral Control

    M. Nienen,1 W. Benjamin,1 L. Kuchenbecker,1,2,3 J. Hecht,1 P. Reinke,1,4 A. Neumann,1 N. Babel.1,4

    1Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany; 2Department of Computer Science, Free University, Berlin, Germany; 3Max Planck Institute for Molecular Genetics, Berlin, Germany; 4Charite University-Medicine, Berlin, Germany.

    Background:BKV-specific T cells play the crucial role in controlling virus reactivation and analyses of their frequencies have been previously performed in different studies. However, nothing…
  • 2015 American Transplant Congress

    Patient and Graft Outcomes Following 3rd, 4th and 5th Renal Transplants – A Single Centre Comparative Study

    I. Loukopoulos, G. Rompianesi, P. Chandak, N. Mamode, F. Calder, N. Kessaris.

    Guy's and St Thomas' Hospital - NHS Foundation Trust, London, United Kingdom.

    Introduction: For patients who have lost their first renal graft, a second kidney transplant is widely accepted as the next best therapeutic option (due to…
  • 2015 American Transplant Congress

    Lack of Utilization of Pre-Emptive Transplantation in Those With Living Donor Kidney Transplants

    A. Sakhuja,1 A. Naik,1 R. Eikstadt,2 P. Shrivastava,1 D. Cibrik,1 M. Samaniego.1

    1Division of Nephrology, University of Michigan, Ann Arbor, MI; 2KECC, University of Michigan, Ann Arbor, MI.

    Introduction: Time spent on dialysis before kidney transplantation (KTx) has been associated with worse outcomes. Pre-emptive transplants are not always possible due shortage of deceased…
  • 2015 American Transplant Congress

    Innate Immune Memory to Allogeneic Non-Self

    H. Dai, A. Williams, M. Oberbarnscheidt, F. Lakkis.

    Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.

    A hallmark of adaptive immunity is the generation of long-lived, antigen-specific memory T, B, and NK lymphocytes that mount strong anamnestic (recall) responses to previously…
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