Am J Transplant, Volume 5, Suppl 3 Archives - Page 26 of 170 - ATC Abstracts

2015 American Transplant Congress
Transplant Glomerulitis in Allograft Kidneys Is Correlated With Antibody-Mediated Rejection
W. Xu, T. Deng.
Department of Pathology, MedStar Georgetown University Hospital and Washington Hospital Center, Washington.
Background: Antibody-mediated rejection manifests with glomerular and peritubular capillary inflammation, transplant glomerulopathy. Transplant glomerulitis is an increasingly recognized lesion in renal transplant biopsies, characterized by…
2015 American Transplant Congress
Intimal Arteritis Associated With Subsequent Graft Dysfunction in ABO-Incompatible Kidney Transplantation
D. Toki,¹ H. Iahida,¹ M. Okumi,¹ T. Shimizu,¹ M. Inui,¹ K. Omoto,¹ H. Shirakawa,¹ K. Unagami,¹ K. Honda,² J. Koike,³ K. Tanabe.¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Pathology, Tokyo Women's Medical University, Tokyo, Japan; ³Pathology, Tama Hospital, Kanagawa, Japan.
Purpose: The diagnosis of acute antibody-mediated rejection (ABMR) is according to following all three evidences: 1) histologic evidence , 2) evidence of interaction with vascular…
2015 American Transplant Congress
Effect of Antibody Mediated Rejection on Long-Term Renal Allograft Function
M. John, A. Smith, I. Dortonne, A. Paramesh, M. Killackey, B. Lee, R. Zhang, J. Buell.
Transplant Institute, Tulane University, New Orleans, LA.
Historically we had poor understanding of chronic rejection attributing it to hypertension and non-compliance. However in the last decade we have begun to understand the…
2015 American Transplant Congress
Three Year Outcomes of Renal Allograft Transplants in African American Recipients Receiving Alemtuzumab for Induction Immunosuppression
P. Vaitla, H. Bohorquez, A. Cohen, A. Cruz, U. Patel, S. Anders, C.-S. Catherine, A. Moiz, S. Guisti, I. Carmody, G. Loss, D. Bruce, T. Reichman, J. Garces.
Ochsner Clinic Foundation, New Orleans, LA.
Background:Induction with Alemtuzumab is well documented to reduce the incidence and severity of acute rejection episodes, which may improve graft survival. Limited data are available…
2015 American Transplant Congress
Survival of Patients With Peripheral Vascular Disease on Kidney Waitlist and After Transplantation: An Analysis of the United State Renal Data System
A. Brar,¹ D. Stefanov,³ R. Jindal,² N. Sumrani,⁴ D. John,⁴ F. Tedla,¹ M. Salifu.¹
¹Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY; ²Department of Surgery, Walter Reed National Military Medical Center, Uniformed Services University of Health Sciences, Bethesda, MD; ³Division of Research, SUNY Downstate School of Medicine, Brooklyn, NY; ⁴Department of Surgery, SUNY Downstate Medical Center, Brooklyn, NY.
Introduction: There is lack of information whether waitlisted dialysis patients with peripheral vascular disease (PVD) benefit from kidney transplantation.Methods: We used a cohort of USRDS…
2015 American Transplant Congress
Weight Loss, But Not Weight Gain Is a Risk Factor for Graft Loss After Kidney Transplantation
E. Hendren, J. Dong, C. Kennedy, T. Myint, C. Rose, O. Johnston, J. Gill, J. Gill.
Division of Nephrology, University of British Columbia, Vancouver, Canada.
Weight gain is common after kidney transplantation. In this analysis of n=92,688 adult 1st kidney transplant recipients with graft survival of ≥ 1 year between…
2015 American Transplant Congress
Sofosbuvir Therapy in Early and Late Post Liver Transplant Setting: A Single Center Experience
X. Zervos,¹ D. Beltran,² B. Ismail,¹ M. Watson,¹ D. Sears,¹ A. Tzakis.¹
¹Liver Transplant, Cleveland Clinic Florida, Weston, FL; ²Pharmacy, Cleveland Clinic Florida, Weston, FL.
Background: Hepatitis C (HCV) treatment has entered a new phase of excitement with new oral therapies. Here we describe our experience of sofosbuvir (SOF) based…
2015 American Transplant Congress
De Novo Once-Daily Tacrolimus in Liver Transplantation: Long-Term Outcomes of a Single Center Cohort of 150 Patients
M. Gastaca, A. Valdivieso, J. Bustamante, P. Ruiz, J. Fernandez, A. Ventoso, M. Testillano, I. Palomares, P. Salvador, M. Prieto, A. Matarranz, M. Suarez, J. Ortiz de Urbina.
Liver Transplantation Unit, Cruces University Hospital. University of the Basque Country, Bilbao, Vizcaya, Spain.
Purpose: To describe the long-term safety and efficacy profile of de novo once-daily tacrolimus (Tac QD) in orthotopic liver transplantation (OLT)Patients and methods: A retrospective…
2015 American Transplant Congress
Outcomes of Solid Organ Transplantation in a National Private Health Plan: Comparison to SRTR Reports
F. Irwin,¹ C. Wu,¹ W. Bannister,² M. Schnitzler,¹ A. Bonagura.¹
¹Optum, Minneapolis; ²Saint Louis University, St. Louis.
The majority of transplant recipients have private health plans. However, there have been few reports using private health plan data describing the outcomes of this…
2015 American Transplant Congress
Dual PI3K-mTOR Inhibition on Human T Cell Activation, Proliferation, and Differentiation: The First Step in the Development of New Immunosuppressants
V. Vilchez,¹ A. Castellanos,¹ D. Butterfield,³ M. Mitov,³ C. Hoopes,¹ F. Marti,² R. Gedaly.¹
¹Department of Surgery - Transplant Section, University of Kentucky, Lexington, KY; ²Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, KY; ³Free Radical Biology in Cancer Shared Resource Facility, University of Kentucky, Lexington, KY.
Background: Regulatory T lymphocytes (Tregs) contribute to transplant tolerance. We have demonstrated that the inhibition of PI3K-mTOR pathway has a major role in the differentiation…