2015 American Transplant Congress
Antibodies Directed Against HLA-DQ Are Significantly Associated to Complement Activation In Vitro
Background: C1q-binding HLA antibodies (HLAabs) have been related to acute rejection and long-term graft loss. The characteristics of these antibodies and factors associated to complement…2015 American Transplant Congress
Mycophenolic Acid Area-Under-Curve (MPA AUC) Levels Sufficient to Prevent Donor-Specific Antibody (DSA) Formation Are Not Associated With Higher Rates of CMV/EBV/BK Viral Infections
PinnacleHealth, Harrisburg, PA.
Background: Prevention of DSA formation and antibody-mediated rejection mandates therapeutic doses of immunosuppressive agents, including MPA. We have shown that MPA AUC monitoring and dose…2015 American Transplant Congress
Body Mass Index (BMI) Mismatch in Deceased Kidney Donation Is an Independent Risk Factor for Graft Failure
IntroductionThe influence of this BMI-mismatch in deceased kidney donors and their recipients on graft survival is so far not well characterized.MethodsRetrospective long-term observational study of…2015 American Transplant Congress
Molecular Features of Kidney Transplant Biopsies Without Allograft Injury in Relation With Type of Induction Therapy
Objective: Molecular evidence of allograft injury might precede histopathological findings of allograft injury. We aimed to investigate if the type of induction therapy effect intragraft…2015 American Transplant Congress
Predicting Obstructive Coronary Artery Disease in Asymptomatic Renal Patients Undergoing Renal Transplantation
Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Almost 50% of asymptomatic patients with End Stage Renal Disease (ESRD) are reported to have significant flow-limiting coronary artery disease (CAD). Our practice involves a…2015 American Transplant Congress
Serum Uric Acid Is Associated With Hypertension in Kidney Donors
Introduction:Uric acid has been linked to the development of hypertension and possibly CKD. Moreover, some preliminary data suggests that lowering uric acid maybe associated with…2015 American Transplant Congress
Results of ABO Incompatible Liver Transplantation Using a Simplified Protocol at a Single Institution
BackgroundABO incompatible (ABOi) living donor liver transplantation (LDLT) has become a feasible option for patients with end-stage liver disease due to development of various desensitization…2015 American Transplant Congress
Improved Renal Function Post-Liver Transplant With Earlier Everolimus Conversion
Calcineurin inhibitors (CNI) play an important role in preventing acute rejection (AR) post-liver transplant. Its long-term use is limited by development of nephrotoxicity. Optimal timing…2015 American Transplant Congress
Transplant Center Quality Assessment: Correlation Between Early Graft Outcomes and Patient-Centered Assessments of Hospital Care
1Surgery, Mayo Clinic Arizona, Phoenix, AZ; 2Surgery, University of Michigan, Ann Arbor, MI.
Background: Patients selecting a transplant center use public reports of outcomes to empower their decision-making. Patient-focused quality measures are lacking in transplantation, but are a…2015 American Transplant Congress
Single Infusion of Donor-Type Splenocytes Treated With Extracorporeal Photopheresis Prior to Transplantation Significantly Prolongs Cardiac Allograft Survival in Mice
Background: Extracorporeal Photopheresis (ECP) is an immune therapy in which blood leukocytes are treated with 8-methoxypsoralen (8-MOP), exposed to UV-A light, and re-infused. This study…
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